AllFam - Database of allergen families Department of Pathophysiology and Allergy Research Medical University of Vienna

AF065: Alpha/beta casein

Pfam domains
PF00363: Casein

Biochemical properties

Caseins can be classified into two families; the first contains the αs1, αs2, and β-caseins, and the second groups the κ-caseins. The α and β-caseins are hydrophobic proteins that are readily precipitated by calcium [1].

Allergological significance

Allergenic members of this family include milk allergens from cow, sheep and goat [2].

References

  1. Holt C, Sawyer L.
    Primary and predicted secondary structures of the caseins in relation to their biological functions.
    Protein Eng 1988, 2, 251-9. [PubMed]
  2. Spuergin P, Walter M, Schiltz E, Deichmann K, Forster J, Mueller H.
    Allergenicity of alpha-caseins from cow, sheep, and goat.
    Allergy 1997, 52, 293-8. [PubMed]

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