The 60S acidic ribosomal protein plays an important role in the elongation step of protein synthesis. This family includes archaebacterial L12, and eukaryotic P0, P1 and P2 .
Members of this family were described as fungal allergens. Alt a 12 from Alternaria alternata and Cla h 12 from Cladosporium herbarum are P1 proteins, while Alt a 5, Cla h 5 and Asp f 8 from Aspergillus fumigatus belong to the P2 family . Autoimmune reacions to human P2 were also described .
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