AF075: SGNH-hydrolase family
- Pfam domains
- PF00657: GDSL-like Lipase/Acylhydrolase
This family includes several lipolytic enzymes with serine as part of the active site, which show a diverse range of activities such as lipase, arylesterase, carbohydrate esterase, and phospholipase .
Hev b 4, a glycoallergen from Hevea brasiliensis latex is a lecithinase . IgE binding to this allergens is directed exclusively to its glycan moieties. A second latex allergen from this protein family, Hev b 13, is also a glycoprotein .
Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases.
Structure 2000, 8, 373-83. [PubMed]
Molecular cloning and immunoglobulin E reactivity of a natural rubber latex lecithinase homologue, the major allergenic component of Hev b 4.
Clin Exp Allergy 2005, 35, 1490-5. [PubMed]
Isolation and characterization of the early nodule-specific protein homologue (Hev b 13), an allergenic lipolytic esterase from Hevea brasiliensis latex.
J Biol Chem 2004, 279, 23933-41. [PubMed]
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