This family is also named pathogenesis-related proteins PR-4. Members of this family are barwin from barley seeds, win1 and win2 from tomato, and tobacco PR-4. Barwin-like proteins contain three conserved disulfide bonds  and are members of the double-psi beta-barrel superfamily . Many family members contain an N-teminal hevein-like domain.
Allergens from this family include the major latex allergen prohevein (Hev b 6.01) and Bra r 2 from turnip.
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