AllFam - Database of allergen families Department of Pathophysiology and Allergy Research Medical University of Vienna

AF104: Patatin family

Pfam domains
PF01734: Patatin-like phospholipase

Biochemical properties

This family consists of various glycoproteins from plants. Patatin accounts for up to 40% of total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids [1]. Members of this family have also been found in vertebrates.

Allergological significance

Patatin is a major potato allergen. Its homology and cross-reactivity to the major Hevea brasiliensis latex allergen Hev b 7 explains the observation of potatoes being one of the plat food involved in the latex-fruit syndrome [2].

References

  1. Shewry PR.
    Tuber storage proteins.
    Ann Bot (Lond) 2003, 91, 755-69. [PubMed]
  2. Seppala U, Palosuo T, Seppala U, Kalkkinen N, Ylitalo L, Reunala T, Turjanmaa K, Reunala T.
    IgE reactivity to patatin-like latex allergen, Hev b 7, and to patatin of potato tuber, Sol t 1, in adults and children allergic to natural rubber latex.
    Allergy 2000, 55, 266-73. [PubMed]

If you have updates or corrections for this entry, please contact the site administrator.

Show a list of allergens from: Patatin family

List allergens from this protein family from sources
with routes of exposure
sort by , show entries per page