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AF113: Ribonuclease N1 and T1
- Pfam domains
- PF00545: ribonuclease
Biochemical properties
Ribonuclease N1 is a guanine-specific ribonuclease from fungi. RNase T1 and other bacterial RNases are related.
Allergological significance
The major Aspergillus allergens Asp f 1 and Asp r 1 belong to this family [1].
References
- Arruda LK, Platts-Mills TA, Fox JW, Chapman MD.
Aspergillus fumigatus allergen I, a major IgE-binding protein, is a member of the mitogillin family of cytotoxins.
J Exp Med 1990, 172, 1529-32. [PubMed]
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