This model is based on concentrated parameters , and was already applied intensively for control studies , biologic assist devices , studies on aortic replacement , perfusion of the isolated heart, and diagnostics of renal artery desease . Further, in cooperation with the Institute of Mathematics of the Technical University of Graz (Styria, Austria) and the Institute of Turbomachinery of the Technical University of Athens (Greece), and the Bioengineering Institute of the University of TelAviv (Israel), our group has done comparisons of numerical simulations of flow fields in pumps , wall shear stress and wall tension with flow visualization studies and in vitro and in vivo experiments. Contact Persons: Heinrich Schima Michael Vollkron Cooperating Institutions: Institute of Mathematics, TU Graz, Austria   Institute of Turbomachinery, TU Athens, Greece   Bioengineering Inst, Univ. of Tel Aviv

Simulation of changes in aortic compliance in vitro

Simulation of a flow field (by Prof. Perktold, TU Graz, based on our in-vivo data)

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References:

1. Schima H, Vollkron M, Boehm H, Rothy W, Haisjackl M, Wieselthaler G, Wolner E.
Weaning of rotary blood pump recipients after myocardial recovery: a computer study of changes in cardiac energetics.
J Thorac Cardiovasc Surg. 127(6):1743-50, 2004

2. Schima H, Lackner B, Prosi M, Perktold K.
Numerical simulation of carotid hemodynamics in patients with rotary blood pump cardiac assist.
Int J Artif Organs. 26(2):152-60, 2003

3. Vollkron M, Schima H, Huber L, Wieselthaler G.
Interaction of the cardiovascular system with an implanted rotary assist device: simulation study with a refined computer model.
Artif Organs. 26(4):349-59, 2002

4. Schima, H., P. Simon, N. Kupilik, L. Huber, G. Wipplinger, R. Scherer, and E. Wolner.
Auswirkung der Wandsteifigkeit von Aortenprothesen auf die Hämodynamik in der Aortenwurzel. Biomedizinsche Technik 41: 52-53, 1996.

5. Schima, H., J. Honigschnabl, W. Trubel, and H. Thoma.
Computer simulation of the circulatory system during support with a rotary blood pump.
ASAIO Transactions 36-3: M252-m254, 1990.

6. Leuprecht A, Perktold K, Prosi M, Berk T, Trubel W, Schima H.
Numerical study of hemodynamics and wall mechanics in distal end-to-side anastomoses of bypass grafts.
J Biomech. 35(2):225-36, 2002

7. Simon-Kupilik N, Schima H, Huber L, Moidl R, Wipplinger G, Losert U, Wolner E, Simon P.
Prosthetic replacement of the aorta is a risk factor for aortic root aneurysm development.
Ann Thorac Surg. 73(2):455-9, .2002

8. Perktold, K., M. Hofer, G. Karner, W. Trubel, and W. Schima. Computer simulation of vascular fluid dynamics and mass transport: Optimal design of arterial bypass anastomoses. ECCOMAS 1-6 1998.

9. Wipplinger, G., M. Rab, W. Girsch, R. Koller, W. Haslik, L. P. Kamolz, S. Sauermann, H. Lanmüller, and H. Schima. A Computer-Model for the evaluation of the hemodynamic efficacy of a skeletal muscle ventricle in counterpulsation mode. 6th Vienna International Workshop on Functional Electrostimulation, ISBN 3-900928-04-5 57-60, 1998.

10. M. Hofer, G. Rappitsch, K. Perktold, W. Trubel, and H. Schima. Numerical study of wall mechanics and fluid dynamics in end-to-side anastomoses and correlation to intimal hyperplasia. J.Biomechanics 29:1297-1308, 1996.

11. Honigschnabel, J: Computermodell des Gesamtkreislaufs zur Untersuchung herzunterstützender Systeme.
Diploma Thesis TU Vienna, Austria 1993.