About Us: Bernhard Schweighofer, Postdoc
Bernhard Schweighofer, Ph.D.
Postdoc
Phone: +43-1-40400-73807
Fax: +43-1-40400- E-mail: bernhard.schweighofer@meduniwien.ac.at
Curriculum Vitae
Present position
Postdoc
Current Project/s
- Development of a genetically modified chick-embryo CAM model to analyze lymphantic vessels
Education
| 2009-2010 | Max Kade Fellowship, Department of Cell Biology, The Scripps Research Institute, La Jolla, California, USA |
|---|---|
| 2008-2009 | Research Associate, Department of Cell Biology, The Scripps Research Institute, La Jolla, California, USA |
| 2008 | Postdoctoral Fellow, Medical University of Vienna, Austria |
| 2002-2008 | PhD Thesis in Genetics & Microbiology: “VEGF-induced genes at the intersection of angiogenesis and inflammation – VEGF, IL-1 and EGF in a combined microarray and pathway analysis”, Institute for Vascular Biology and Thrombisis Research (Prof. Dr. Hofer), Medical University of Vienna, Austria |
| 1997-2002 | Study of Biology (Genetics & Microbiology), University of Vienna, Vienna Biocenter, Austria |
| 1992-1997 | Study of Biology (Zoology), University of Vienna, Austria |
Publications
- Bekes E.M., Schweighofer B.**, Kupriyanova T.A., Zajac E., Ardi V.C., Quigley J.P., Deryugina E.I. (2011) Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 determine coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation. Am J Pathol, 179(3), 1455-1470 **shared first-authorship
- Testori J, Schweighofer B., Helfrich I., Sturtzel C., Lipnik K., Gesierich S., Nasarre P., Hofer-Warbinek R. , Bilban M., Augustin H.G., Hofer E. (2011) The VEGF-regulated transcription factor HLX controls the expression of guidance cues and negatively regulates sprouting of endothelial cells. Blood, 117(9); 2735-44
- Ardi V.C., Van den Steen P.E., Opdenakker G., Schweighofer B., Deryugina E.I., Quigley J.P. (2009) Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway. J Biol Chem. 284(38), 25854-66.
- Schweighofer B., Testori J., Sturtzel C., Sattler S., Mayer H., Wagner O., Bilban M., Hofer E. (2009) The VEGF-induced transcriptional response comprises gene clusters at the crossroad of angiogenesis and inflammation. Thromb Haemost. 102(3), 544-54.
- Schweighofer, B., Schultes, J., Pomyje, J. and Hofer, E. (2007) Signals and genes induced by angiogenic growth factors in comparison to inflammatory cytokines in endothelial cells. Clin Hemorheol Microcirc, 37, 57-62.
- Hofer, E. and Schweighofer, B. (2007) Signal transduction induced in endothelial cells by growth factor receptors involved in angiogenesis. Thromb Haemost, 97, 355-363.
- Schabbauer, G., Schweighofer, B., Mechtcheriakova, D., Lucerna, M., Binder, B.R. and Hofer, E. (2007) Nuclear factor of activated T cells and early growth response-1 cooperate to mediate tissue factor gene induction by vascular endothelial growth factor in endothelial cells. Thromb Haemost, 97, 988-997.
- Sobanov, Y., Bernreiter, A., Derdak, S., Mechtcheriakova, D., Schweighofer B., Duchler, M., Kalthoff, F. and Hofer, E. (2001) A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex. Eur J Immunol, 31, 3493-3503.
Awards
- Max Kade Fellowship from the Austrian Academy of Sciences. 2009.
