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About Us: Peter Petzelbauer, M.D.

Petzelbauer Peter
Peter Petzelbauer, M.D. Professor of Microvascular Research Phone: +43-1-40400-73786 or 73532 Fax: +43-1-40400-73595 E-mail:

Curriculum Vitae

Present position

Professor of Microcirculation of the Skin, University of Vienna Medical School
Clinical responsibility: in charge of Dermatopatholgy
Research responsibility: Principal Investigator of the Skin & Endothelium Research Division (SERD)

Education

Since 1994 Venia docendi for Dermatology
1992 - 1993 Postdoctoral fellowship at the Boyer Center for Molecular Medicine
Yale University School of Medicine, New Haven, USA
(Director: Prof. Dr. Jordan Pober)
1986 - 1992 Residency training in Dermatology, Department of Dermatology I,
University of Vienna Medical School (Chairman: Prof. Dr. Klaus Wolff)
Residency completed on January 1st, 1991 (including qualification as dermatopathologist)
1976 - 1983 University of Vienna Medical School, Vienna, Austria
Graduated May 1983

Other activities

Founder and CSO of Fibrex Medical Research and Development GesmbH (http://www.fibrexmedical.com)

Publications

  1. Swoboda A, Schanab O, Tauber S, Bilban M, Berger W, Petzelbauer P, Mikula M. 2012. MET expression in melanoma correlates with a lymphangiogenic phenotype. Hum Mol Genet.[Epub ahead of print]
  2. Niederleithner H, Heinz M, Tauber S, Bilban M, Pehamberger H, Sonderegger S, Knöfler M, Bracher A, Berger W, Loewe R, Petzelbauer P. 2012. Wnt1 is anti-lymphangiogenic in a melanoma mouse model. J Invest Dermatol.[Epub ahead of print]
  3. Hoeth M, Niederleithner H, Bilban M, Mayer H, Hofer-Warbinek R, Wagner O, Petzelbauer P, de Martin R. 2012. The transcription factor Sox18 controls a pattern of neuronal guidance molecules in endothelial cells. PLoS one ;7(1):e30982.
  4. Capper D, Berghoff AS, Magerle M, Ilhan A, Wöhrer A, Hackl M, Pichler J, Pusch S, Meyer J, Habel A, Petzelbauer P, Birner , von Deimling A, Preusser M. 2012. Immunohistochemical testing of BRAF V600E status in 1120 tumor tissue samples of patients with brain metastases. Acta Neuropathol. ;123(2):223-33.
  5. Höller C, Petzelbauer P, Loewe.R. 2011. Neue therapeutische Strategien beim Melanom. Spectrum Onkologie 2011:5:62-65
  6. Schneider S, Thurnher D, Kloimstein P, Leitner V, Petzelbauer P, Pammer J, Brunner M, Erovic BM. 2011. Expression of the sonic hedgehog pathway in squamous cell carcinoma of the skin and the mucosa of the head and neck. Head Neck. 33(2):244-50
  7. Sörensen I, Rong S, Susnik N, Gueler F, Shushakova N, Albrecht M, Dittrich AM, von Vietinghoff S, Becker JU, Melk A, Bohlmann A, Reingruber S, Petzelbauer P, Haller H, Schmitt R. 2011. Fibrinogen derived Bß15–42 improves renal allograft survival by attenuating reperfusion injury and inflammation. J Am Soc Nephrol. 22(10):1887-96
  8. Swoboda A, Rasin-Streden D, Schanab O, Okamoto I, Pehamberger H, Petzelbauer P, Mikula M. 2011. Identification of genetic disparity between primary and metastatic melanoma in human patients. Genes, Chromosomes & Cancer. 50(9):680-8
  9. Zeyda M, Gollinger K, Todoric J, Kiefer FW, Keck M, Aszmann O, Prager G, Zlabinger GJ, Petzelbauer P, Stulnig TM. 2011. Osteopontin Is an Activator of Human Adipose Tissue Macrophages and Directly Affects Adipocyte Function. Endocrinology. 152(6):2219-27
  10. Reinisch CM, Mildner M, Petzelbauer P, Pammer J. 2011. Embryonic stem cell factors undifferentiated transcription factor-1 (UFT-1) and reduced expression protein-1 (REX-1) are widely expressed in human skin and may be involved in cutaneous differentiation but not in stem cell fate determination. Int J Exp Pathol. 92(5):326-32
  11. Kretschy D, Gröger M, Zinkl D, Petzelbauer P, Koellensperger G, Hann S. 2011. High-throughput flow injection analysis of labeled peptides in cellular samples—ICP-MS analysis versus fluorescence based detection. Int J Mass Spectrom Int. 307:105-111
  12. Leksa V, Loewe R, Binder B, Schiller HB, Eckerstorfer P, Forster F, Cardona AS, Ondrovicová G, Kutejová E, Steinhuber E, Breuss J, Drach J, Petzelbauer P, Binder BR, Stockinger H. 2011. Soluble M6P/IGF2R Released by TACE Controls Angiogenesis via Blocking Plasminogen Activation. Circ Res.108(6):676-85
  13. Stary G, Klein I, Brüggen MC, Kohlhofer S, Brunner PM, Spazierer D, Müllauer L, Petzelbauer P, Stingl G. 2010. Host Defense Mechanisms in Secondary Syphilitic Lesions. A Role for IFN-{gamma}-/IL-17-Producing CD8+ T Cells. Am J Pathol. Nov;177(5):2421-32
  14. Siller-Matula JM, Bayer G, Bergmeister H, Quehenberger P, Petzelbauer P, Friedl P, Mesteri I, Jilma B. 2010. An experimental model to study isolated effects of thrombin in vivo. Thromb Res. Sep 23
  15. Schneider S, Thurnher D, Kloimstein P, Leitner V, Petzelbauer P, Pammer J, Brunner M, Erovic BM. 2010. Expression of the Sonic hedgehog pathway in squamous cell carcinoma of the skin and the mucosa of the head and neck. Head Neck. May 19.
  16. Hallén J, Petzelbauer P, Schwitter J, Henning R, Buser P, Atar D. 2010. Impact of time to therapy on the efficacy of FX06 in acute ST elevation myocardial infarction: a F.I.R.E. substudy. EuroIntervention. Apr;5(8):946-52.
  17. Brunner M, Thurnher D, Pammer J, Heiduschka G, Petzelbauer P, Schmid C,Schneider S,Erovic BM. 2010. Expression of the Sonic hedgehog pathway in squamous cell carcinoma of the skin and the mucosa of the head and neck. Head & Neck. in press
  18. Brunner M, Thurnher D, Pammer J, Heiduschka G, Petzelbauer P, Schmid C, Schneider S, Erovic BM. 2010. Expression of hedgehog signaling molecules in Merkel cell carcinoma. Head & Neck. Mar;32(3):333-40.
  19. Leitner V, Weingast J, Harmankaya K, Walochnik J, Pehamberger H, Petzelbauer P, Auer H, Binder M. 2010. Leishmaniasis in the tongue of an immunocompetent man. Am J Trop Med Hyg. Apr;82(4):597-9
  20. Woegerbauer M, Thurnher D, Houben R, Pammer J, Kloimstein P, Heiduschka G, Petzelbauer P, Erovic BM. 2010. Expression of the tetraspanins CD9, CD37, CD63, and CD151 in Merkel cell carcinoma: strong evidence for a post-transcriptional fine-tuning of CD9 gene expression. Modern Pathology. May;23(5):751-62.
  21. Wiedemann D, Schneeberger S, Friedl P, Zacharowski K, Zacharowski K, Wick N, Boesch F, Margreiter R, Laufer G, Petzelbauer P, Semsroth S. 2010. The fibrin-derived peptide Bβ15-42 significantly attenuates ischemia/reperfusion injury in a cardiac transplant model. Transplantation Apr 15;89(7):824-9.
  22. Lichtenberger BM, Tan PK, Niederleithner H, Petzelbauer P, Sibilia M. 2010. Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development. Cell. Jan 22;140(2):268-279.
  23. Pfistershammer K, Petzelbauer P, Stingl G, Mastan P, Chott A, Jäger U, Skrabs C, Geusau A. 2010. Methotrexate-induced primary cutaneous diffuse large B-cell lymphoma with an 'angiocentric' histological morphology. Clin Exp Dermatol. Jan;35(1):59-62
  24. Valero T, Steele S, Neumüller K, Bracher A, Niederleithner H, Pehamberger H, Petzelbauer P, Loewe R.Combination of dacarbazine and dimethylfumarate efficiently reduces melanoma lymph node metastasis. J Invest Dermatol. 2010 Apr;130(4):1087-94.
  25. Hallén J, Buser P, Schwitter J, Petzelbauer P, Geudelin B, Fagerland MW, Jaffe AS, Atar D. 2009 Relation of cardiac troponin I measurements at 24 and 48 hours to magnetic resonance-determined infarct size in patients with ST-elevation myocardial infarction. Am J Cardiol. Dec 1;104(11):1472-7.
  26. Pflegerl P, Janig E, Vesely P, Zenz R, Steiner G, Meixner A, Petzelbauer P, Wolf P, Soleiman A, Egger G, Moriggl R, Wagner EF  and Kenner L. 2009. Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signalling. PNAS 106(48): 20423-2043-28.
  27. Matt U, Warszawska JM, Bauer M,Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P and Knapp S. 2009. Bβ15-42 protects against acid-induced acute lung injury and secondary Pseudomonas pneumonia in vivo. Am. J. Respir. Crit. Care Med. 180(12): 1208-1217.
  28. Gröger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, Bukin E, Friedl P, Zinkl D, Hofer-Warbinek R, Zacharowski K, Petzelbauer P and Reingruber S. Peptide Bβ15-42 preserves endothelial barrier function in shock. 2009. plos ONE 4(4): e5391
  29. Loewe R, Gattringer KB, Petzelbauer P. 2009. Janeway Lesions may present with inconspicuous histological features. J Cut Pathol. Oct;36(10):1095-8.
  30. Koellensperger G, Gröger M, Zinkl D, Petzelbauer P, Hann S. 2008. Quantification of elemental labeled peptides in cellular uptake studies. J Anal Atom Spectrom 80, 264-271, 2009
  31. Roesner JP, Petzelbauer P, Koch A, Tran N, Iber T, Mutz C, Vollmar B, Nöldge-Schomburg GEF, Zacharowski K. 2008. Part 2: A double blind, single center, sub chronic reperfusion trial evaluating FX06 following haemorrhagic shock in pigs. Resus 5, 3:720-729
  32. Atar D, Petzelbauer P, Schwitter J, Huber K, Rensing B, Kasprzak JD, Butter C, Grip L, Hansen PR, Süselbeck T, Clemmensen P, Marin-Galiano M, Geudelin B, Buser PT, for the F.I.R.E. Investigators. 2009. Effect of Intravenous FX06 as an Adjunct to Primary Percutaneous Coronary Intervention for Acute ST Segment Elevation Myocardial Infarction (Results of the F.I.R.E. Trial). J Am Coll Cardiol 53:720-9
  33. Roesner JP, Petzelbauer P, Zacharowski PA, Koch A, Tran N, Iber T, Vagts DA, Scheeren TWL, Reingruber S, Vollmar B, Nöldge-Schomburg GEF & Zacharowski K. 2009. The fibrin-derived peptide Bβ15-42 reduces pulmonary and myocardial damage in a pig model of trauma and hemorrhagic shock. Crit care med Feb;37(2):598-605.
  34. Pfistershammer K, Petzelbauer P, Mastan P, Chott A, Jäger U, Skrabs C, Geusau A. 2008. MTX-induced primary cutaneous diffuse large B-cell lymphoma with an ’angiocentric’ histological morphology. Clin Exp Dermatol 2009 May 21. [Epub ahead of print]
  35. Wick N, Haluza D, Gurnhofer E, Raab I, Kasimir MT, Prinz M, Steiner CW, Reinisch C, Howorka A, Giovanoli P, Buchsbaum S, Krieger S, Tschachler E, Petzelbauer P, Kerjaschki D. 2008. Lymphatic precollectors contain a novel, specialized subpopulation of podoplaninlow, CCL27 secreting lymphatic endothelial cells Am J Pathol 173:1202-9
  36. Brunner M, Thurnher D, Pammer J, Geleff S, Heiduschka G, Reinisch CM, Petzelbauer P, Erovic BM. 2008. Expression of VEGF-A/C, VEGF-R2, PDGF-B1 and B2, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma. Mod Pathol 21:876-84.
  37. Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot, A, Maurer D. 2007. Down-Modulation of CXCR3 Surface Expression and Function in CD8+ T Cells from Cutaneous T Cell Lymphoma Patients. J Immunol 179:4272-82
  38. Dzirlo L, Hubner M, Müller C, Blaha B, Formann E, Dellinger C, Petzelbauer P, Müllauer L, Huber K, Kneussl M, Gschwantler M. 2007. A mimic of sarcoidosis. Lancet 369:1832
  39. Zacharowski K, Petzelbauer P. 2007. The peptide Bbeta15-42: A new treatment option for the heart in shock? Inflammation Res 56: S194-S195
  40. Gröger M, Niederleithner H, Kerjaschki D and Petzelbauer P. 2007. A previously unknown dermal blood vessel phenotype in skin inflammation. J Invest Dermatol 127:2893-2900
  41. Roesner J, Petzelbauer P, Koch A, Mersmann J, Zacharowski PA, Boehm O, Reingruber S, Pasteiner W, Henning R, Mascher H, Mascher D, Barthuber C, Nöldge-Schomburg G, Scheeren TW, Zacharowski K. 2007. The fibrin-derived peptide Bβ15-42 is cardioprotective in a pig model of myocardial ischemia-reperfusion injury. Crit Care Med 35:1730-1735.
  42. Zacharowski K, Zacharowski PA, Friedl P, Mastan P, Koch A, Boehm O, Rother RP, Reingruber S, Henning R, Emeis JJ, Petzelbauer P. 2007. A preclinical study in three different centers on the effects of the fibrin-derived peptide Bβ15-42 in rodent models of myocardial ischemia-reperfusion. Shock 27, 631-7
  43. Henning R, Zacharowski K, Petzelbauer P. 2006. FX06 (fibrin-derived peptide Bbeta15-42) – A Potential Candidate for Myocardial Reperfusion Therapy. Drugs of the future 31, 811-19
  44. Loewe R, Valero T, Kremling S, Pratscher B, Kunstfeld R, Pehamberger H and Petzelbauer P. 2006. Dimethylfumarate impairs melanoma growth and metastasis. Cancer Res 66, 11888-96
  45. Streubel B, Scheucher B, Valencak J, Huber D, Petzelbauer P, Trautinger F, Weihsengruber F, Mannhalter C, Cerroni L, Chott A. 2006. Molecular Cytogenetic Evidence of t(14;18)(IGH;BCL2) in a Substantial Proportion of Primary Cutaneous Follicle Center Lymphomas. Am J Surg Pathol 30:529-536.
  46. Holnthoner W, Kerenyi M, Gröger M, Kratochvill F, Petzelbauer P. 2006. Regulation of Matrilysin Expression in Endothelium by Fibroblast Growth Factor-2. Biochem Biophys Res Commun 242: 725-733
  47. Zacharowski K, Zacharowski P, Reingruber S, Petzelbauer P. 2006. Fibrin(ogen) and its fragments in the pathophysiology and treatment of myocardial infarction. J Mol Med 84:469-77
  48. Petzelbauer P, Zacharowski P, Miyazaki Y, Friedl P, Wickenhauser G, Castellino F, Gröger M, Wolff K, Zacharowski K. 2005. The fibrin-derived peptide Bbeta15-42 protects the myocardium against ischemia/reperfusion injury. Nat Med 11 298-304
  49. Loewe R, Palatin M, Petzelbauer P. 2005. Degos´ disease with inconspicuous clinical course. J Europ Acad Derm Ven 19: 477-480
  50. Gröger M, Loewe R, Holnthoner W, Embacher R, Pillinger M, Herron GS, Wolff K and Petzelbauer P. 2004. IL-3 induces expression of lymphatic phenotypic markers Prox-1 and podoplanin in human endothelial cells. J Immunol 173:7161-9
  51. Kohrgruber N, Gröger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, Stingl G, Rot A, Maurer D. 2004. Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol 173 6592-6602
  52. Loewe R, Kittler H, Fischer G, Faé I, Wolff K, Petzelbauer P. 2004. Mutations in the BRAF kinase gene correlate with rapid melanocytic lesion growth. J Invest Dermatol 123:733-736
  53. Rüger B, Giurea A, Wanivenhaus AH, Zehetgruber H, Hollemann D, Yanagida G, Gröger M, Petzelbauer P, Smolen JS, Hoecker P, Fischer MB. 2004. Endothelial precursor cells in the synovial tissue of patients with rheumatoid arthritis and osteoarthritis. Arth Rheumat 50:2157-2166
  54. Kunstfeld R, Wickenhauser G, Umek W, Michaelis, U., Teifel, M., Naujoks, K., Wolff K., Petzelbauer, P. 2003. Paclitaxel encapsulated in cationic liposomes diminishes tumor angiogenesis and melanoma growth in a ‘humanized’ SCID mouse model. J Invest Dermatol 120:476-482
  55. Loewe R, Püspök-Schwarz M und Petzelbauer P. 2003. Apomorphin-Pigmentierung. Hautarzt 54:58-63
  56. Atrasheuskaya, A., Petzelbauer, P., Fredeking, T.M., Ignatyev, G. 2003. Anti-TNF antibody treatment reduces mortality in experimental Dengue virus infection. FEMS Immunol Med Mic 35:33-42
  57. Holnthoner, W., Gröger, M., Pillinger, M., Wolff, K., Ashton A.W., Albanese, C., Neumeister, P., Pestell R.G., Petzelbauer, P. 2002. Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells. J Biol Chem 277:45847-45853
  58. Loewe R, Holnthoner W, Gröger M, Pillinger M, Gruber F, Mechtcheriakova D, Hofer E, Wolff K, Petzelbauer P. 2002. Dimethylfumarate inhibits TNF-induced nuclear entry of NF-B/p65 in human endothelial cells. J Immunol 168: 4781-7
  59. Gröger M., P. Petzelbauer..2001. Mikrovaskuläre Endothelzellen in der Haut exprimieren den Makrophagen Mannose Rezeptor (180kD) in situ und in vitro. Modern aspects of Immunobiology 2:28-29
  60. Wolff, K., Komar, M., Petzelbauer, P. 2001. Clinical and histopathological aspects of ctaneous mastocytosis. Leukemia Res 25:519-528
  61. Wolf, H.M., V. Thon, H. Gulle, S. Lechleitner, M.M. Eibl, and P. Petzelbauer. 2001. Cell-specific residual expression of MHC class II molecules in twin brothers with a new form of MHC class II deficiency. Br J Hematology 115:460-471
  62. Loewe R, Pillinger M, Jirovsky D, Wiegrebe W, de Martin R, Mrowietz U, Gröger M, Holnthoner W, Wolff K, Petzelbauer P. 2001. Dimethylfumarate inhibits TNF-induced CD62E expression in a NFκB-dependent manner. J Invest Dermatol 117:1363-1368
  63. Kunstfeld, R., P. Petzelbauer, G., Wickenhauser, I. Schlenz, K. Korak, K. Vinzenz, J. Holle. 2001. The prefabricated scapula flap consists of syngeneic bone, connective tissue and a self-assembled epithelial coating. Plast Reconstruct Surg 108:1908-1914
  64. Haller, A., E. Elzubi, P. Petzelbauer. 2001. A female patient with localized syringolymphoid hyperplasia with alopecia and anhidrosis. J Am Acad Dermatol 45:127-130
  65. Kunstfeld, R., P. Petzelbauer. 2001. A unique case of a benign disseminated angioproliferation combining features of Kaposi’s sarcoma and diffuse dermal angioproliferation. J Am Acad Dermatol 45:601-605
  66. Halama, T., M. Gröger, M. Pillinger, G. Staffler, E. Prager, H. Stockinger, W. Holnthoner, S. Lechleitner, K. Wolff, P. Petzelbauer. 2001. Platelet/endothelial cell adhesion molecule-1 and VE-cadherin / ß-catenin cooperatively regulate FGF-induced modulations of adherens junction functions. J Invest Dermatol 116:110-117
  67. Petzelbauer, P., Halama. T., Gröger, M. 2000. Endothelial adherens junctions. J Invest Dermatol Symp Proc 5:10-13
  68. Gröger, M., W. Holnthoner, D. Maurer, S. Lechleitner, K. Wolff, B. Mayr, W. Lubitz, and P. Petzelbauer. 2000. Dermal microvascular endothelial cells express the 180 kD macrophage mannose receptor in situ and in vitro. J Immunol 165:5428-5434
  69. Halama, T., G. Staffler, S. Hoch, H. Stockinger, K. Wolff, P. Petzelbauer. 1999. VE-cadherin but not PECAM-1-based cell to cell contacts convey the maintenance of a quiescent endothelial monolayer. Int Arch All Immunol 120:237-244.
  70. Gröger, M., T. Matsumura, N. Kohrgruber, D. Maurer, K. Wolff, P. Petzelbauer. 1999. A standardized, computer-assisted in vitro assay for the assessment of neutrophil transmigration across endothelial monolayers. J Immunol Meth 222:101-109
  71. Gröger, M., G. F. Fischer, K. Wolff, P. Petzelbauer. 1999. Immune complexes from vasculitis patients bind to endothelial Fc receptors independent of the allelic polymorphism of FcgRIIa. J Invest Dermatol. 113:56-60
  72. Lechleitner, S., R. Kunstfeld, C. Messeritsch-Fanta, K. Wolff, P. Petzelbauer. 1999. Peripheral node addressins are expressed on skin endothelial cells. J Invest Dermatol 113:410-414
  73. Lechleitner, S., J. Gille, D. R. Johnson, P. Petzelbauer. 1998. Interferon enhances tumor necrosis factor-induced vascular cell adhesion molecule 1 (CD106) expression in human endothelial cells by an interferon-related factor 1-dependent pathway. J Exp Med. 187:2023-2030.
  74. Maurer, D., E. Fiebiger, B. Reininger, C. Ebner, P. Petzelbauer, Guo-Ping Shi, H. A. Chapmann, G. Stingl. 1998. FceRI on dendritic cells delivers IgE-bound multivalent antigens into a cathepsin S-dependent pathway of MHC Class II presentation. J Immunol. 161:2731-2739.
  75. Kunstfeld, R., S. Lechleitner, K. Wolff, P. Petzelbauer. 1998. MCP-1 and MIP-1a are most effficient in recruiting T cells into the skin in vivo. J Invest Dermatol. 111:1040-1044.
  76. Ure, I., B. Partsch, K. Wolff, P. Petzelbauer. 1998. GM-CSF increases wound fluid IL-8, but does not accelerate wound healing in healthy subjects. Brit J Dermatol. 138:277-282.
  77. Maurer, D., C. Ebner, B. Reininger, P. Petzelbauer, E. Fiebiger, G. Stingl. 1997. Mechanisms of Fc epsilon RI-IgE-facilitated allergen presentation by dendritic cells. Adv Exp Med Biol. 417:175-178.
  78. Petzelbauer, P., M. Gröger. 1997. Cutaneous immune complex vasculitis: the role of Fc gamma receptors in precipitating the disease. J Dermatol. 24:730-731.
  79. Kunstfeld, R., S. Lechleitner, M. Gröger, K. Wolff and P. Pe Petzelbauer tzelbauer. 1997. HECA-452+ T Cells migrate through superficial vascular plexus but not through deep vascular plexus endothelium. J Invest Dermatol. 108:343-348.
  80. Pickl, W., O. Majdic, G. Fischer, P. Petzelbauer, I. Faé, M. Waclavicek, J. Stöckl, C. Scheinecker, T. Vidicki, H. Aschauer, J. P. Johnson, W. Knapp. 1997. MUC18/MCAM (CD146): An activation antigen of human T lymphocytes. J Immunol. 158:2107-2115.
  81. Weninger, W., M. Rendl, J. Pammer, W. Grin, P. Petzelbauer, E. Tschachler. 1997. Differences in tumor microvessel density between squamous cell carcinomas and basal cell carcinomas may relate to their different biologic behavior. J Cut Pathol. 24:364-369.
  82. Matsumura, T., K. Wolff, P. Petzelbauer. 1997. Endothelial cell tube formation depends on cadherin-5 and CD31 interactions with filamentous actin. J Immunol. 158:3408-3416.
  83. Gröger, M., G. Sarmay, E. Fiebiger, K. Wolff, P. Petzelbauer. 1996. Dermal microvascular endothelial cells express CD32 receptors in vivo and in vitro. J Immunol. 156:1549-1556.
  84. Petzelbauer, P., M. Gröger, R. Kunstfeld, E. Petzelbauer, K. Wolff. 1996. Human delayed type hypersensitivity reaction in a SCID mouse engrafted with human T cells and autologous skin. J Invest Dermatol. 107:576-581.
  85. Petzelbauer, P., C. A. Watson, S. E. Pfau, J. S. Pober. 1995. IL-8 and angiogenesis: evidence that human endothelial cells lack IL-8 receptors and do not respond in vitro. Cytokine. 7:267-272.
  86. Watson, C. A., P. Petzelbauer, J. Zhou, R. Pardi, J. R. Bender. 1995. Contact-dependent endothelial cell class II HLA gene activation induced by natural killer cells is mediated by IFN-g -dependent and independent mechanisms. J Immunol. 154:3222-3232.
  87. Murray, A. G., P. Petzelbauer, C. C. W. Hughes, J. Costa, P. Askenase, J. S. Pober. 1994. Human T cell-mediated destruction of allogeneic dermal microvessels in a SCID mouse. Proc Natl Acad Sci USA. 91:9146-9150.
  88. Petzelbauer, P., J. S. Pober, A. Key, I. M. Braverman. 1994. Inducibility and expression of microvascular endothelial adhesion molecules in lesional, perilesional and uninvolved skin of psoriatic patients. J Invest Dermatol. 103:300-305.
  89. Petzelbauer, P., J. R. Bender, J. Wilson, J. S. Pober. 1993. Heterogeneity of dermal microvascular endothelial cell antigen expression and cytokine responsiveness in situ and in cell culture. J Immunol. 151:5062-5072.
  90. Petzelbauer, P., D. Födinger, C. Rappersberger, B. Volc Platzer, K. Wolff. 1993. CD68 positive epidermal cells. J Invest Dermatol. 101:256-261.
  91. Petzelbauer, P., K. Wolff, G. Tappeiner. 1992. Necrobiosis lipoidica: treatment with systemic corticosteroids. Brit J Dermatol. 126:542-545.
  92. Petzelbauer, P., K. Wolff. 1992. Effects of cyclosporin A on resident and passenger immune cells of normal human skin and UV-induced erythema reactions. Brit J Dermatol. 127:560-565.
  93. Petzelbauer, P., M. Binder, P. Nikolakis, B. Ortel, H. Hönigsmann. 1992. Severe sun sensitivity and the presence of antinuclear antibodies in patients with polymorphous light eruption-like lesions. A form fruste of photosensitive lupus erythematosus? J Am Acad Dermatol. 26:68-74.
  94. Aberer, W., A. Steiner, P. Petzelbauer. 1991. Klinik, Diagnostik, Therapie and Prophylaxe der Penicillinallergie. Therapiewoche. 6:165-172.
  95. Petzelbauer, P., G. Stingl, K. Wolff, B. Volc Platzer.1991. Cyclosporin A suppresses ICAM-1 expression by papillary endothelium in healing psoriatic plaques. J Invest Dermatol. 96:362-369.
  96. Petzelbauer, P., H. Hönigsmann, K. Langer, B. Anegg, R. Strohal, A. Tanew, K. Wolff.1990. Cyclosporin A in combination with photochemotherapy (PUVA) in the treatment of psoriasis. Brit J Dermatol. 123:641-647.
  97. Petzelbauer, P., K. Konrad.1990. Polypous clear cell acanthoma. Am J Dermatopathology. 12:393-395.
  98. Petzelbauer, P., I. Hammer, K. Konrad.1989. Cornu cutaneum. Hautarzt. 40:556-558.
  99. Petzelbauer P, K. Konrad, K Wolff.1989. Staphylococcal scalded skin syndrome in 2 adults with acute kidney failure. Hautarzt. 40:90-93.

Book chapters

  1. Petzelbauer P, Loewe R, Pober JS: 2011. Endothelium. In: Goldsmith, Katz, Gilchrest, Paller, Leffell, Wolff, Eds. Dermatology in General Medicine, 8th Edition, Mac Graw Hill, NY
  2. Petzelbauer P, Loewe R. 2008. Dimethylfumarate and Cancer. In: Schwab, Ed. Encyclopedia of Cancer, 2nd edition, p871-3.
  3. Petzelbauer P, Gröger M, Loewe R, Kunstfeld R. 2007. Endothelium and skin. In: Aird, Ed. Endothelial Biomedicine. Cambridge U Press, p1431-1443
  4. Petzelbauer P, Pen L, Pober JS: 2007. Endothelium. In: Wolff, Goldsmith, Katz, Gilchrest, Paller, Leffell, Eds. Dermatology in General Medicine, 7th Edition, Mac Graw Hill, NY. p1500-1530
  5. Petzelbauer P, Schechner J, Pober JS. 2003. Endothelium. In: Freedberg, Eisen, Wolff, Austen, Goldsmith, Katz, Eds. Dermatology in General Medicine, 6th Edition, Mac Graw Hill, NY. p216-229
  6. Petzelbauer P, Schechner J, Pober JS. 1999. Endothelium. In: Freedberg, Eisen, Wolff, Austen, Goldsmith, Katz, Fitzpatrick, Eds. Dermatology in General Medicine, 5th Edition, Mac Graw Hill, NY. p305-320

Awards

  1. Best of Biotech 2010
  2. Houska award 2006
  3. Erste Bank award 2005 for NatMed 2005
  4. Researcher of the month 3/2005, award of the University of Vienna Medical School
  5. Poster award ÖGD 2004 for JI 2004
  6. AESCA award 2004 for JID 2004
  7. Förderungspreis des Fonds der Stadt Wien für innovative interdiziplinäre Krebsforschnung 2003 for JID 2003
  8. Poster award Angiogenesis Leiden 2003 for NatMed 2005
  9. Hebra award 2002
  10. Best of Biotech award 2001
  11. Hoechst award 1999 for JID 1997
  12. Karl Landsteiner award 1998 for JEM 1998
  13. Theodor Billroth award 1997 for JI 1997
  14. Poster award ADF 1997 for JI 1997
  15. Unilever award 1996 for JID 1996
  16. AESCA award 1991 for JID 1991
  17. Max Kade fellowship 1992-3

Patents

  1. Means and methods for treating a disease or disorder related to lymphangiogenesis or preventing metastasis WO 2011/S3116EP
  2. Peptides as active agents to stabilize biological barriers WO2011157819
  3. Bbeta(15-42) and its analogues combined with cyclosporine for treatment of reperfusion injury EP2334324
  4. Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition EP2328925
  5. Methods of screening for compounds having anti-inflammatory activity EP2193370
  6. Peptides and peptide derivatives as well as pharmaceutical compositions containing the same EP1987062
  7. Pharmaceutical composition for treating haemorrhagic shock and its consecutive symptoms EP2110136
  8. Process for determining the anti-inflammatory effect of a peptide EP1962887
  9. Use of peptides derived from the b beta chain of human fibrinogen for the treatment of shock EP1691827
  10. Fumaric acid derivatives as nf-kappab inhibitors EP1408947
  11. Peptide and/or proteins and their use for the manufacture of a therapeutic and/or preventive medicament EP1586586
  12. Immunodeficient animal model for studying t cell-mediated immune responses. US 5,602,305

Financial support

Wiener Wissenschafts-, Forschungs- und Technologiefonds

2011 - 2014 A new treatment concept for lung injury (LS11-008)

Fonds zur Förderung der Wissenschaftlichen Forschung (FWF)

1994 - 1997 The Hu-SCID mouse as a model for studying human endothelium - human T-cell interactions (P10317)
1997 - 2000 Structure and function of endothelial adherens junction proteins (P12240)
2001 - 2002 The role of fibrin(ogen) in T cell inflammation (P15099)
2005 - 2008 Role of Tcf in vessel formation (S9402-B11)
2006 - 2009 Fibrinbruchstücke und Vaskular Leak (Bridgeprogramm des FFG +FWF #811037/10332-SCK/SAI)
2008 - 2011 Role of Tcf-dependent transcription in lymphogenic melanoma spread (P20940-B11)
2009 - 2011 Elemental labeling of peptides (P21739-B11); cooperative grant with Priv.Doz. Stefan Hann, Department of Chemistry, University of Natural Resources and Applied Life Sciences, Vienna, Austria
2010 - 2012 Effects of peptide FX06 on vasoconstriction (Bridgeprogramm des FFG +FWF #822725)
2011 - 2014 Mechanisms of Wnt-1 induced reduction of VEGF-C expression (P24022)

Nationalbank/Jubiläumsfonds

1995 - 1996 Dermal microvascular endothelial cells as antigen-presenting cells in a syngeneic system (5202)
1997 - 2000 The role of endothelial Fc receptors in the pathogenesis of cutaneous leukocytoclastic vasculitis (6688)
2002 - 2003 Lef/Tcf dependent transcription in endothelial cells (9299)
2008 - 2009 Angiogenesis as a risk factor for the development of invasive squamous cell carcinoma (12742)

Niarchos Foundation

1999 - 2000 Novel strategies for the treatment of advanced melanoma: Antiangiogenesis
2002 - 2004 Strategies for melanoma II: Antiangiogenesis

Company collaborations

1999 Liposome targeting to angiogenic tissues. (MBT, Munich, Germany)
2000 Effects of fumaric acid esters on endothelial cell functions. (Fumarpharm, Zürich, CH)
2000 - 2001 Liposomes for anti-angiogenic treatment in melanoma. (MBT, Munich, Germany)
2001 Effects of fumaric acid esters on nuclear translocation of NF-kB (Fumarpharm, Zürich, CH)
2002 - 2006 Fumaric acid ester binding to cellular proteins/Treatment of melanoma. (Fumarpharm, Zürich, CH)
2002 - 2005 Peptides for treatment of myocardial infarction. (Fibrex Medical R&D, A)
2005 - 2007 Peptides for the treatment of Shock; FFG grant #810295 in cooperation with Fibrex
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