Gerhard Zlabinger - Clinical Experimental Immunology

It is a central concern in modern immunology to recognise how the immune system succeeds to simultaneously defeat potentially harmful invaders and to spare host tissue. Both the knowledge about triggering appropriate reactions in case of imminent threat for the host and the insight into the highly complex regulatory mechanisms operating to sustain the integrity of an individual are
essential to foster the development of effective strategies for interference in caseof disturbed or unwanted immune reactivity as operative in allergy, autoimmunity, malignancy or transplantation. A longstanding interest of my research group concentrates on the issue of naturally occurring ways of immunomodulation as particularly operating in local immunity and onclinical conditions in consequence of inappropriate immune reactivity as observed after transplantation or in autoimmune diseases. Identification of immunological deregulation as early as possibly and the understanding of the ongoing processes are pivotal for early diagnosis and the development as well as implementation of purposeful interference strategies.

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