Our long-term research interest is to understand molecular mechanisms that regulate the development and function of immune cells. The research in our laboratory focuses on studies to investigate epigenetic and transcriptional control mechanisms that regulate CD8 coreceptor gene expression, on the identification of genes that control developmental processes such as CD4/CD8 cell fate decisions during T cell differentiation, and on studies to reveal the various roles of Tec family kinases in different cell lineages of the immune system. The experimental strategies to address our research interests include biochemical and molecular approaches, retroviral-mediated gene transduction into hematopoietic stem cells, and mouse molecular genetics tools.
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Molecular Mechanisms of T Cell Development
Tec Family Kinases and Signalling Pathways in Immune Cells
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© ellmeier lab 2000-2010, institute of immunology
medical university of vienna, austria