2013

Evstatiev R, Alexeeva O, Bokemeyer B, Chopey I, Felder M, Gudehus M, Iqbal T, Khalif I, Marteau P, Stein J, Gasche C; FERGI Study Group. "Ferric carboxymaltose prevents recurrence of anemia in patients with inflammatory bowel disease."Clin Gastroenterol Hepatol. 2013 Mar;11(3):269-77. doi: 10.1016/j.cgh.2012.10.013 [PubMed] [pdf]

Khare V, Lyakhovich A, Dammann K, Lang M, Borgmann M, Tichy B, Pospisilova S, Luciani G, Campregher C, Evstatiev R, Pflueger M, Hundsberger H, Gasche C. "Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1." Biochem Pharmacol. 2013 Jan 15;85(2):234-44. doi: 10.1016/j.bcp.2012.10.026 [PubMed] [pdf]

2012

Campregher C, Schmid G, Ferk F, Knasmüller S, Khare V, Kortüm B, Dammann K, Lang M, Scharl T, Spittler A, Roig AI, Shay JW, Gerner C, Gasche C. "MSH3-Deficiency Initiates EMAST without Oncogenic Transformation of Human Colon Epithelial Cells" PLoS One. 2012;7(11):e50541. doi: 10.1371/journal.pone.0050541 [PlosONE] [pdf]

Dolak W, Kulnigg-Dabsch S, Evstatiev R, Gasche C, Trauner M, Püspök A."A randomized head-to-head study of small-bowel imaging comparing MiroCam and EndoCapsule."Endoscopy. 2012 Nov;44(11):1012-20. doi: 10.1055/s-0032-1310158 [PlosONE] [pdf]

Sachar DB, Jewell D, Gasche C, Braun J. "Inflammatory bowel disease."International Journal of Inflammation, Volume 2012 (2012), Article ID 341052, 2 pages, doi:10.1155/2012/341 [PubMed] [pdf]

Kulnigg-Dabsch S, Evstatiev R, Dejaco C, Gasche C. "Effect of Iron Therapy on Platelet Counts in Patients with Inflammatory Bowel Disease-Associated Anemia."PLoS ONE, 6 April 2012, Volume 7, Issue 4, e34520. [PlosONE] [pdf]

Honeder C, Campregher C, Zens B, Scharl T, Gasche C. "Improvement of replication fidelity by certain mesalazine derivatives."Int J Oncol. 2012 May;40(5):1331-8. doi: 10.3892/ijo.2012.1381. Epub 2012 Feb 21. [PubMed] [pdf]

2011

Campregher C, Gasche C. "Aminosalicylates." Best Pract Res Clin Gastroenterol. 2011 Aug;25(4-5):535-46. [PubMed] [pdf]

Evstatiev R, Gasche C. "Iron sensing and signalling." Gut. 2011 Oct 19. [Epub ahead of print].[PubMed] [pdf]

Evstatiev R, Marteau P, Iqbal T, Khalif IL, Stein J, Bokemeyer B, Chopey IV, Gutzwiller FS, Riopel L, Gasche C; FERGI study group. "FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease." Gastroenterology. 2011 Jun 12. [Epub ahead of print].[PubMed] [pdf]

Finsterbusch M, Khare V, Campregher C, Evstatiev R, Gasche C. "An intracytoplasmic IL-10 receptor variant permits rapid reduction in STAT3 activation." Genes Immun. 2011 Jun 9. doi: 10.1038/gene.2011.12.[PubMed] [pdf]

Paul G, Khare V, Gasche C. "Inflamed gut mucosa: downstream of interleukin-10." Eur J Clin Invest. 2011 Jun 1. doi: 10.1111/j.1365-2362.2011.02552.x. [PubMed] [pdf]

Gasche C, Evstatiev R, Haas T, Kaser A, Knoflach P, Petritsch W, Weiss G, Reinisch W. "Diagnosis and Treatment of Iron Deficiency and Anaemia in Inflammatory Bowel Diseases. Consensus of the Austrian IBD Working Party." Z Gastroenterol. 2011 May;49(5):627-632. Epub 2011 Apr 27. [PubMed] [pdf]

Lyakhovich A, Michlmayr A, Bakulina A, Gerner C, Oehler R, Gasche C. "Interaction of Mesalasine (5-ASA) with Translational Initiation Factors eIF4 Partially Explains 5-ASA Anti-Inflammatory and Anti-Neoplastic Activities." Med Chem. 2011 Mar 1;7(2):92-8. [PubMed] [pdf]

2010

Ferlitsch A, Silberhumer GR, Noda W, Birsan T, Desai D, Kumar A, Rao GV, Khakar A, Gomez NA, Gasche C. "A novel endoscopic device for repeated right-side colonic access during colonoscopy (with video)." Gastrointest Endosc. 2010 May;71(6):1052-5. [PubMed] [pdf]

Campregher C, Scharl T, Nemeth M, Honeder C, Jascur T, Boland CR, Gasche C. "The Nucleotide Composition of Microsatellites Impacts Both Replication Fidelity and Mismatch Repair in Human Colorectal Cells." Hum Mol Genet. 2010 Jul 1;19(13):2648-57. Epub 2010 Apr 26. [PubMed] [pdf]

Campregher C, Honeder C, Chung H, Carethers JM, Gasche C. "Mesalazine Reduces Mutations in Transforming Growth Factor {beta} Receptor II and Activin Type II Receptor by Improvement of Replication Fidelity in Mononucleotide Repeats." Clin Cancer Res. 2010 Mar 2. [PubMed] [pdf]

Ghaith OA, El Halabi MM, Abdul-Baki H, Gasche C, Nemeth M, Sharara AI. "Lack of correlation between IL-10R1 S138G loss-of-function allele and IBD in the Lebanese population." Inflamm Bowel Dis. 2010 Feb 23. [PubMed] [pdf]

Weiss G, Gasche C. "Pathogenesis and treatment of anemia in inflammatory bowel disease." Haematologica. 2010 Feb;95(2):175-8. [PubMed] [pdf]

2009

Lyakhovich A, Gasche C. "Systematic review: molecular chemoprevention of colorectal malignancy by mesalazine." Aliment Pharmacol Ther. 2009 Nov 5. [PubMed] [pdf]

Campregher C, Luciani MG, Biesenbach P, Evstatiev R, Lyakhovich A, Gasche C. "The position of the amino group on the benzene ring is critical for mesalamine's improvement of replication fidelity." Inflamm Bowel Dis. 2009 Oct 9. [PubMed] [pdf]

Hermann J, Gruber S, Neufeld JB, Grundtner P, Graninger M, Graninger WB, Berghold A, Gasche C. "IL10R1 loss-of-function alleles in rheumatoid arthritis and systemic lupus erythematosus." Clin Exp Rheumatol. 2009 Jul-Aug;27(4):603-8. [PubMed] [pdf]

Goel A, Mittal A, Evstatiev R, Nemeth M, Kruis W, Stolte M, Boland CR, Gasche C. "In vivo effects of mesalazine or E.Coli Nissle 1917 on microsatellite instability in ulcerative colitis." Aliment Pharmacol Ther. 2009 Jun 25. [PubMed] [pdf]

Kulnigg S, Teischinger L, Dejaco C, Waldhör T, Gasche C. "Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment." Am J Gastroenterol. 2009 Jun;104(6):1460-7. Epub 2009 Apr 21. [PubMed] [pdf]

Andrews JM, Travis SP, Gibson PR, Gasche C. "Systematic review: does concurrent therapy with 5-ASA and immunomodulators in inflammatory bowel disease improve outcomes?" Aliment Pharmacol Ther. 2009 Mar 1;29(5):459-69. Epub 2008 Dec 11. [PubMed] [pdf]

Gruber SG, Gloria Luciani M, Grundtner P, Zdanov A, Gasche C. "Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1." Eur J Immunol. 2008 Dec;38(12):3365-75.  [PubMed] [pdf]

Grundtner P, Gruber S, Murray SS, Vermeire S, Rutgeerts P, Decker T, Lakatos PL, Gasche C. "The IL-10R1 S138G loss-of-function allele and ulcerative colitis." Genes Immun. 2009 Jan;10(1):84-92. Epub 2008 Sep 18.  [PubMed] [pdf]

2008

Kulnigg S, Stoinov S, Simanenkov V, Dudar LV, Karnafel W, Garcia LC, Sambuelli AM, D'Haens G, Gasche C. "A Novel Intravenous Iron Formulation for Treatment of Anemia in Inflammatory Bowel Disease: The Ferric Carboxymaltose (FERINJECT((R))) Randomized Controlled Trial." Am J Gastroenterol. 2008 Mar 26 [PubMed] [pdf]

Campregher C, Luciani MG, Gasche C. "Activated Neutrophils Induce an hMSH2-dependent G2/M Checkpoint Arrest and Replication Errors at a (CA)13-repeat in Colon Epithelial Cells." Gut. 2008 Jun;57(6):780-7. Epub 2008 Feb 13.  [PubMed] [pdf]

Silberhumer G, Birsan T, Noda W, Unger E, Mayr W, Lang S, Prager G, Gasche C. "Design and Instrumentation of New Devices for Performing Appendectomy at Colonoscopy." Gastrointestinal Endoscopy, 2008 May 1.[PubMed] [pdf]

Gasche C, Nemeth M, Grundtner P, Willheim C, Ferenci P, Schwarzenbacher R. "Evolution of Crohn's Disease-Associated Nod2 Mutations." Immunogenetics, 2008 Feb;60(2):115-20. Epub 2008 Feb 6.  [PubMed] [pdf]

Kindler J, Schosser A, Stamenkovic M, Schloegelhofer M, Leisch F, Hornik K, Aschauer HN, Gasche C. "Tourette´s Syndrome is not associated with interleukin-10 receptor 1 variants on chromosome 11q23.3." Psychiatry Research 157(1-3):235-9, 2008 [PubMed] [pdf]

2007

Schosser A, Aschauer HN, Wildenauer DB, Schwab SG, Albus M, Maier W, Schloegelhofer M, Leisch F, Hornik K, Shaw SH, Gasche C. "Homozygosity of the interleukin-10 receptor 1 G330R allele is associated with schizophrenia." Am J Med Genet B Neuropsychiatr Genet. 144(3):347-50, 2007 [PubMed] [pdf]

Gasche C, Berstad A, Befrits R, Beglinger C, Dignass A, Erichsen K, Gomollon F, Hjortswang H, Koutroubakis I, Kulnigg S, Oldenburg B, Rampton D, Schroeder O, Stein J, Travis S, Van Assche G. "Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases." Inflamm Bowel Dis. 2007 Dec;13(12):1545-53. [PubMed] [pdf]

Bartel G, Weiss I, Turetschek K, Schima W, Püspök A, Waldhoer T, Gasche C. "Ingested matter affects intestinal lesions in Crohn's disease." Inflamm Bowel Dis. 2007 Oct 11; [PubMed] [pdf]

David T. Rubin, Marcia R. Cruz-Correa, Christoph Gasche, Jeremy R. Jass, Gary R. Lichtenstein, Elizabeth A. Montgomery,PRobert H. Riddell, Matthew D. Rutter, Thomas A. Ullman, Fernando S. Velayos and Steven Itzkowitz. "Colorectal Cancer Prevention in Inflammatory Bowel Disease and the Role of 5-Aminosalicylic Acid: a Clinical Review and Update" Inflamm Bowel Dis 2007;13:000–000 [PubMed] [pdf]

Luciani MG, Campregher C, Gasche C. "Aspirin blocks Proliferation in Colon Cells by inducing a G1-Arrest and Apoptosis through Activation of the Checkpoint Kinase ATM" Carcinogenesis. 2007 Oct;28(10):2207-17. Epub 2007 May 17. [PubMed] [pdf]

Luciani MG, Campregher C, Fortune JM, Kunkel TA, Gasche C. "5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint" Gastroenterology. 2007 Jan;132(1):221-35. [PubMed] [pdf]

2006

Kulnigg S, Gasche C. "Systematic review: managing anaemia in Crohn's disease" Aliment Pharmacol Ther. 2006 Dec;24(11-12):1507-23. [PubMed] [pdf]

Gasche C, Kulnigg S. "Intravenous Iron in Inflammatory Bowel Disease" Semin Hematol. 2006 Oct; 34(6) S18-S22. [Abstract] [pdf]

2005

Boland CR, Luciani MG, Gasche C, Goel A. "Infection, inflammation, and gastrointestinal cancer" Gut. 2005 Sep;54(9):1321-31. [PubMed] [pdf]

Gasche C, Goel A, Natarajan L, Boland CR. "Mesalazine improves replication fidelity in cultured colorectal cells" Cancer Res. 2005 May 15;65(10):3993-7. [PubMed] [pdf]

2004

Gasche C, Lomer M C E, Cavill I, Weiss G. "Iron, anaemia, and inflammatory bowel diseases" Gut 2004;53:1190–1197. [PubMed] [pdf]

2003

Gasche C, Chang CL, Natarajan L, Goel A, Rhees J, Young DJ, Arnold CN, Boland CR.  "Identification of frame-shift intermediate mutant cells" Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1914-9. [PubMed] [pdf]

2000

Gasche C. "Anemia in IBD: The Overlooked Villain" Inflamm Bowel Dis. 2000 May;6(2):142-150; discussion 151. [PubMed] [pdf]

Gasche C, Scholmerich J, Brynskov J, D'Haens G, Hanauer SB, Irvine EJ, Jewell DP, Rachmilewitz D, Sachar DB, Sandborn WJ, Sutherland LR. "A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998." Inflamm Bowel Dis. 2000 Feb;6(1):8-15. [PubMed] [pdf]

1997

Gasche C, Dejaco C, Waldhoer T, Tillinger W, Reinisch W, Fueger GF, Gangl A, Lochs H. "Intravenous iron and erythropoietin for anemia associated with Crohn disease. A randomized, controlled trial." Ann Intern Med. 1997 May 15;126(10):782-7. [PubMed] [pdf]