Laboratory for Molecular Cancer Chemoprevention

 

 

PUBLICATIONS

2017

Lang M., Berry D., Passecker K., Mesteri I., Bhuju S., Ebner F., Sedlyarov V., Evstatiev R., Dammann K., Loy A., Kuzyk O., Kovarik P., Khare V., Beibel M., Roma G., Meisner-Kober N. and Gasche C. "HuR small molecule inhibitor elicits differential effects in adenomatosis polyposis and colorectal carcinogenesis" Cancer Research, 2017 Feb 20 https://doi.org/10.1158/0008-5472.CAN-15-1726 [Cancer Research] [pdf]


2016

Baumgartner M., Lang., Gasche C. "Eiserne Neuigkeiten aus dem Bakterienreich: Wie die Art der Eisenersatztherapie die Darmflora bei chronisch entzündlichen Darmerkrankungen beeinflusst." Gastro&Hepa-News, 3/16 [Gastro&Hepa-News] [pdf]

Jimenez K., Gasche C., Auerbach M. "On both sides of the ocean" Blood Transfus. 2016 May;14(2):197-8. doi: 10.2450/2016.0304-15. [Blood Transfusion] [pdf]

Jimenez K., Lang M. "Diagnostic approach to iron deficiency anemia" Wien Med Wochenschr. 2016 Oct;116(13-14):402-410. DOI: 10.1007/s10354-016-0495-5. [Wiener Medizinische Wochenschrift] [pdf]

Tortola L, Nitsch R, Bertrand MJ, Kogler M, Redouane Y, Kozieradzki I, Uribesalgo I, Fennell LM, Daugaard M, Klug H, Wirnsberger G, Wimmer R, Perlot T, Sarao R, Rao S, Hanada T, Takahashi N, Kernbauer E, Demiröz D, Lang M, Superti-Furga G, Decker T, Pichler A, Ikeda F, Kroemer G, Vandenabeele P, Sorensen PH, Penninger JM. "The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate." Cell Rep. 2016 Sep 20;16(12):3414; doi: 10.1016/j.celrep.2016.08.072. [Cell Reports] [pdf]

Chenzhang Shi, Yongzhi Yang, Yang Xia, Yoshinaga Okugawa, Jun Yang, Yong Liang, Hongqi Chen, Peng Zhang, Feng Wang, Huazhong Han, Wen Wu, Renyuan Gao, Christoph Gasche, Huanlong Qin, Yanlei Ma, Ajay Goel "Novel evidence for an oncogenic role of microRNA-21 in colitis-associated colorectal cancer" Gut 2016;65:1470-1481; doi:10.1136/gutjnl-2014-308455 [Gut] [pdf ]


2015

Juniku-Shkololli A., Manxhuka-Kerliu S., Ahmetaj H., Khare V., Zekaj S. "Expression of immunohistochemical markers of progression in pre-cancerous and cancerous human colon: correlation with serum vitamin D levels." Anticancer Res. 2015; Mar;35(3):1513-20. doi: 10.2450/2016.0304-15. [Anticancer Research] [pdf]

Kyle Dammann, Vineeta Khare, Felix Harpain, Michaela Lang, Azra Kurtovic, Ildiko Mesteri, Rayko Evstatiev and Christoph Gasche"PAK1 promotes intestinal tumor initiation. Cancer Prevention Research, 2015 Aug 24, doi:10.1158/1940-6207.CAPR-15-0205-T [Cancer Prev Res (Phila).] [pdf]

K. Jimenez, V. Khare, R. Evstatiev, S. Kulnigg-Dabsch, M. Jambrich, H. Strobl, C. Gasche " Increased expression of HIF2a during iron deficiency- associated megakaryocytic differentiation. Journal of Thrombosis and Haemostasis, 2015 Jun;13(6):1113-27. doi: 10.1111/jth.12884. Epub 2015 Apr 23 [J Thromb Haemost.] [pdf]

Vineeta Khare, Gregor Paul, Oliver Movadat, Adrian Frick, Manuela Jambrich, Anita Krnjic, Brigitte Marian, Friedrich Wrba, and Christoph Gasche " IL-10R2 overexpression promotes IL-22/STAT3 signaling in colorectal carcinogenesis. Cancer Immunology Research, 2015 Jun 30; doi: 10.1158/2326-6066.CIR-15-0031 [Cancer Immunol Res.] [pdf]

Vineeta Khare, Kyle Dammann, Mario Asboth, Anita Krnjic, Manuela Jambrich, and Christoph Gasche " Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer. Inflammatory Bowel Diseases, 2015 Feb;21(2):287-96; doi: 10.1097/MIB.0000000000000281 [Inflamm Bowel Dis.] [pdf]

Kristine Jimenez, MD, Stefanie Kulnigg-Dabsch, MD, and Christoph Gasche, MD "Management of Iron Deficiency Anemia. Gastroenterology & Hepatology, April 2015, Vol. 11, Issue 4 [Gastroenterology & Hepatology] [pdf]

Tariq Iqbal, Jürgen Stein, Naveen Sharma, Stefanie Kulnigg-Dabsch, Senthil Vel, Christoph Gasche " Clinical Significance of C-Reactive Protein Levels in Predicting Responsiveness to Iron Therapy in Patients with Inflammatory Bowel Disease and Iron Deficiency Anemia. Digestive Diseases and Sciences, May 2015; Vol. 60, Issue 5, pp 1375-1381 [Dig Dis Sci.] [pdf]

Gasche C, Ahmad T, Tulassay Z, Baumgart DC, Bokemeyer B, Büning C, Howaldt S, Stallmach A; AEGIS Study Group. " Ferric maltol is effective in correcting iron deficiency anemia in patients with inflammatory bowel disease: results from a phase-3 clinical trial program. Inflammatory Bowel Diseases, 2015 Mar;21(3) [Inflamm Bowel Dis.] [pdf]

Dammann K., Khare V, Lang M, Claudel T, Harpain F, Granofszky N, Evstatiev R, Williams JM, Pritchard DM, Watson A, Gasche C " PAK1 modulates a PPARgamma/NF-kappaB cascade in intestinal inflammation. 2015 May 31, Biochimica et Biophysica Acta 1853 (2015) 2349-2360; doi: 10.1016/j.bbamcr.2015.05.031 [Biochim Biophys Acta] [pdf]

Giuseppe Amato, MD, Tudor Birsan, MD, Erna Granic, MD, Gerd Silberhumer, MD, Giovanni Cassata, MVD, Antonino Agrusa, MD, Roberto Puleio, MVD, Giorgio Romano, MD, Susanna Lang, MD, Wayne Noda, BSBME, Christoph Gasche, MD " Vacuum inversion and securing of distal colonic pseudodiverticula with novel spiked O-rings Volume 81, No. 3: 2015 Gastrointestinal Endoscopy; http://dx.doi.org/10.1016/j.gie.2014.09.051 [Gastrointestinal Endoscopy] [pdf]

M. Lang, C. Gasche " Chemoprevention of Colorectal Cancer Dig Dis. 2015;33(1):58-67. doi: 10.1159/000366037. Epub 2014 Dec 17. [Digestive Diseases] [pdf]

M. Lang, J. Karner-Hanusch, C. Gasche " Positive Effekte von NSAR auf den Gastrointestinaltrakt Journal für Gastroenterologische und Hepatologische Erkrankungen 2015; 13 (1): 14-23 [Journal für Gastroenterologische und Hepatologische Erkrankungen] [pdf]

2014

Arnulf Ferlitsch, MD, Andreas Puespoek, MD, Christoph Gasche, MD " Endoscopic imaging of the vermiform appendix Gastrointest Endosc. 2014 Dec;80(6):1156-60. doi: 10.1016/j.gie.2014.07.048. Epub 2014 Oct 3. [Gastrointestinal Endoscopy] [pdf]

Yaron Niv, Gabriela Moeslein, Hans F.A. Vasen, Judith Karner-Hanusch Jan Lubinsky, Christoph Gasche " Quality of colonoscopy in Lynch syndrome Endoscopy International Open 2014; 02: E252- E255 [Endoscopy International Open] [pdf]

Bernard Favrat, Katharina Balck, Christian Breymann, Michael Hedenus, Thomas Keller, Anna Mezzacasa, Christoph Gasche "Evaluation of a Single Dose of Ferric Carboxymaltose in Fatigued, Iron-Deficient Women- PREFER a Randomized, Placebo-Controlled StudyPLoS One. 2014 Apr 21;9(4):e94217. doi: 10.1371/journal.pone.0094217 [PLoS One] [pdf]

Kortüm B, Campregher C, Lang M, Khare V, Pinter M, Evastatiev R, Schmid G, Mittlböck M, Scharl T, Kucherlapati M, Edelmann W, Gasche C "Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2loxP/loxP Villin-Cre miceGUT. November 26, 2014. Gut doi:10.1136/gutjnl-2014-307663 [Gut] [pdf]

Kyle Dammann, Vineeta Khare, Christoph Gasche "Tracing PAKs from GI inflammation to cancer.GUT. May 7, 2014. 10.1136/gutjnl-2014-306768 [Gut] [pdf]

Evstatiev R, Bukaty A, Jimenez K, Kulnigg-Dabsch S, Surman L, Schmid W, Eferl R, Lippert K, Scheiber-Mojdehkar B, Kvasnicka HM, Khare V, Gasche C. "Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin.American Journal of Hematology, Vol. 89, No. 5, May 2014 [PubMed] [pdf]

Vineeta Khare, Michaela Lang, Kyle Dammann, Christoph Campregher, Alex Lyakhovich, Christoph Gasche "Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells.Biochemical Pharmacology 87 (2014) 312-320. [PubMed] [pdf]

2013

Kulnigg-Dabsch S, Schmid W, Howaldt S, Stein J, Mickisch O, Waldhör T, Evstatiev R, Kamali H, Volf I, Gasche C. "Iron Deficiency Generates Secondary Thrombocytosis and Platelet Activation in IBD: the Randomized, Controlled ThromboVIT Trial.Inflamm Bowel Dis 2013;0:1-8. [PubMed] [pdf]

Lang M, Borgmann M, Oberhuber G, Evstatiev R, Jimenez K, Dammann KW, Jambrich M, Khare V, Campregher C, Ristl R, Gasche C. "Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling.Mol Cancer. 2013 May 13;12(1):41. doi:10.1186/1476-4598-12-41 [PubMed] [pdf]

Evstatiev R, Alexeeva O, Bokemeyer B, Chopey I, Felder M, Gudehus M, Iqbal T, Khalif I, Marteau P, Stein J, Gasche C; FERGI Study Group. "Ferric carboxymaltose prevents recurrence of anemia in patients with inflammatory bowel disease."Clin Gastroenterol Hepatol. 2013 Mar;11(3):269-77. doi: 10.1016/j.cgh.2012.10.013 [PubMed] [pdf]

Khare V, Lyakhovich A, Dammann K, Lang M, Borgmann M, Tichy B, Pospisilova S, Luciani G, Campregher C, Evstatiev R, Pflueger M, Hundsberger H, Gasche C. "Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1." Biochem Pharmacol. 2013 Jan 15;85(2):234-44. doi: 10.1016/j.bcp.2012.10.026 [PubMed] [pdf]


2012

Campregher C, Schmid G, Ferk F, Knasmüller S, Khare V, Kortüm B, Dammann K, Lang M, Scharl T, Spittler A, Roig AI, Shay JW, Gerner C, Gasche C. "MSH3-Deficiency Initiates EMAST without Oncogenic Transformation of Human Colon Epithelial Cells" PLoS One. 2012;7(11):e50541. doi: 10.1371/journal.pone.0050541 [PlosONE] [pdf]

Dolak W, Kulnigg-Dabsch S, Evstatiev R, Gasche C, Trauner M, Püspök A."A randomized head-to-head study of small-bowel imaging comparing MiroCam and EndoCapsule."Endoscopy. 2012 Nov;44(11):1012-20. doi: 10.1055/s-0032-1310158 [PlosONE] [pdf]

Sachar DB, Jewell D, Gasche C, Braun J. "Inflammatory bowel disease."International Journal of Inflammation, Volume 2012 (2012), Article ID 341052, 2 pages, doi:10.1155/2012/341 [PubMed] [pdf]

Kulnigg-Dabsch S, Evstatiev R, Dejaco C, Gasche C. "Effect of Iron Therapy on Platelet Counts in Patients with Inflammatory Bowel Disease-Associated Anemia."PLoS ONE, 6 April 2012, Volume 7, Issue 4, e34520. [PlosONE] [pdf]

Honeder C, Campregher C, Zens B, Scharl T, Gasche C. "Improvement of replication fidelity by certain mesalazine derivatives."Int J Oncol. 2012 May;40(5):1331-8. doi: 10.3892/ijo.2012.1381. Epub 2012 Feb 21. [PubMed] [pdf]


2011

Campregher C, Gasche C. "Aminosalicylates." Best Pract Res Clin Gastroenterol. 2011 Aug;25(4-5):535-46. [PubMed] [pdf]

Evstatiev R, Gasche C. "Iron sensing and signalling." Gut. 2011 Oct 19. [Epub ahead of print].[PubMed] [pdf]

Evstatiev R, Marteau P, Iqbal T, Khalif IL, Stein J, Bokemeyer B, Chopey IV, Gutzwiller FS, Riopel L, Gasche C; FERGI study group. "FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease." Gastroenterology. 2011 Jun 12. [Epub ahead of print].[PubMed] [pdf]

Finsterbusch M, Khare V, Campregher C, Evstatiev R, Gasche C. "An intracytoplasmic IL-10 receptor variant permits rapid reduction in STAT3 activation." Genes Immun. 2011 Jun 9. doi: 10.1038/gene.2011.12.[PubMed] [pdf]

Paul G, Khare V, Gasche C. "Inflamed gut mucosa: downstream of interleukin-10." Eur J Clin Invest. 2011 Jun 1. doi: 10.1111/j.1365-2362.2011.02552.x. [PubMed] [pdf]

Gasche C, Evstatiev R, Haas T, Kaser A, Knoflach P, Petritsch W, Weiss G, Reinisch W. "Diagnosis and Treatment of Iron Deficiency and Anaemia in Inflammatory Bowel Diseases. Consensus of the Austrian IBD Working Party." Z Gastroenterol. 2011 May;49(5):627-632. Epub 2011 Apr 27. [PubMed] [pdf]

Lyakhovich A, Michlmayr A, Bakulina A, Gerner C, Oehler R, Gasche C. "Interaction of Mesalasine (5-ASA) with Translational Initiation Factors eIF4 Partially Explains 5-ASA Anti-Inflammatory and Anti-Neoplastic Activities." Med Chem. 2011 Mar 1;7(2):92-8. [PubMed] [pdf]


2010

Ferlitsch A, Silberhumer GR, Noda W, Birsan T, Desai D, Kumar A, Rao GV, Khakar A, Gomez NA, Gasche C. "A novel endoscopic device for repeated right-side colonic access during colonoscopy (with video)." Gastrointest Endosc. 2010 May;71(6):1052-5. [PubMed] [pdf]

Campregher C, Scharl T, Nemeth M, Honeder C, Jascur T, Boland CR, Gasche C. "The Nucleotide Composition of Microsatellites Impacts Both Replication Fidelity and Mismatch Repair in Human Colorectal Cells." Hum Mol Genet. 2010 Jul 1;19(13):2648-57. Epub 2010 Apr 26. [PubMed] [pdf]

Campregher C, Honeder C, Chung H, Carethers JM, Gasche C. "Mesalazine Reduces Mutations in Transforming Growth Factor {beta} Receptor II and Activin Type II Receptor by Improvement of Replication Fidelity in Mononucleotide Repeats." Clin Cancer Res. 2010 Mar 2. [PubMed] [pdf]

Ghaith OA, El Halabi MM, Abdul-Baki H, Gasche C, Nemeth M, Sharara AI. "Lack of correlation between IL-10R1 S138G loss-of-function allele and IBD in the Lebanese population." Inflamm Bowel Dis. 2010 Feb 23. [PubMed] [pdf]

Weiss G, Gasche C. "Pathogenesis and treatment of anemia in inflammatory bowel disease." Haematologica. 2010 Feb;95(2):175-8. [PubMed] [pdf]


2009

Lyakhovich A, Gasche C. "Systematic review: molecular chemoprevention of colorectal malignancy by mesalazine." Aliment Pharmacol Ther. 2009 Nov 5. [PubMed] [pdf]

Campregher C, Luciani MG, Biesenbach P, Evstatiev R, Lyakhovich A, Gasche C. "The position of the amino group on the benzene ring is critical for mesalamine's improvement of replication fidelity." Inflamm Bowel Dis. 2009 Oct 9. [PubMed] [pdf]

Hermann J, Gruber S, Neufeld JB, Grundtner P, Graninger M, Graninger WB, Berghold A, Gasche C. "IL10R1 loss-of-function alleles in rheumatoid arthritis and systemic lupus erythematosus." Clin Exp Rheumatol. 2009 Jul-Aug;27(4):603-8. [PubMed] [pdf]

Goel A, Mittal A, Evstatiev R, Nemeth M, Kruis W, Stolte M, Boland CR, Gasche C. "In vivo effects of mesalazine or E.Coli Nissle 1917 on microsatellite instability in ulcerative colitis." Aliment Pharmacol Ther. 2009 Jun 25. [PubMed] [pdf]

Kulnigg S, Teischinger L, Dejaco C, Waldhör T, Gasche C. "Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment." Am J Gastroenterol. 2009 Jun;104(6):1460-7. Epub 2009 Apr 21. [PubMed] [pdf]

Andrews JM, Travis SP, Gibson PR, Gasche C. "Systematic review: does concurrent therapy with 5-ASA and immunomodulators in inflammatory bowel disease improve outcomes?" Aliment Pharmacol Ther. 2009 Mar 1;29(5):459-69. Epub 2008 Dec 11. [PubMed] [pdf]

Gruber SG, Gloria Luciani M, Grundtner P, Zdanov A, Gasche C. "Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1." Eur J Immunol. 2008 Dec;38(12):3365-75.  [PubMed] [pdf]

Grundtner P, Gruber S, Murray SS, Vermeire S, Rutgeerts P, Decker T, Lakatos PL, Gasche C. "The IL-10R1 S138G loss-of-function allele and ulcerative colitis." Genes Immun. 2009 Jan;10(1):84-92. Epub 2008 Sep 18.  [PubMed] [pdf]


2008

Kulnigg S, Stoinov S, Simanenkov V, Dudar LV, Karnafel W, Garcia LC, Sambuelli AM, D'Haens G, Gasche C. "A Novel Intravenous Iron Formulation for Treatment of Anemia in Inflammatory Bowel Disease: The Ferric Carboxymaltose (FERINJECT((R))) Randomized Controlled Trial." Am J Gastroenterol. 2008 Mar 26 [PubMed] [pdf]

Campregher C, Luciani MG, Gasche C. "Activated Neutrophils Induce an hMSH2-dependent G2/M Checkpoint Arrest and Replication Errors at a (CA)13-repeat in Colon Epithelial Cells." Gut. 2008 Jun;57(6):780-7. Epub 2008 Feb 13.  [PubMed] [pdf]

Silberhumer G, Birsan T, Noda W, Unger E, Mayr W, Lang S, Prager G, Gasche C. "Design and Instrumentation of New Devices for Performing Appendectomy at Colonoscopy." Gastrointestinal Endoscopy, 2008 May 1.[PubMed] [pdf]

Gasche C, Nemeth M, Grundtner P, Willheim C, Ferenci P, Schwarzenbacher R. "Evolution of Crohn's Disease-Associated Nod2 Mutations." Immunogenetics, 2008 Feb;60(2):115-20. Epub 2008 Feb 6.  [PubMed] [pdf]

Kindler J, Schosser A, Stamenkovic M, Schloegelhofer M, Leisch F, Hornik K, Aschauer HN, Gasche C. "Tourette´s Syndrome is not associated with interleukin-10 receptor 1 variants on chromosome 11q23.3." Psychiatry Research 157(1-3):235-9, 2008 [PubMed] [pdf]


2007

Schosser A, Aschauer HN, Wildenauer DB, Schwab SG, Albus M, Maier W, Schloegelhofer M, Leisch F, Hornik K, Shaw SH, Gasche C. "Homozygosity of the interleukin-10 receptor 1 G330R allele is associated with schizophrenia." Am J Med Genet B Neuropsychiatr Genet. 144(3):347-50, 2007 [PubMed] [pdf]

Gasche C, Berstad A, Befrits R, Beglinger C, Dignass A, Erichsen K, Gomollon F, Hjortswang H, Koutroubakis I, Kulnigg S, Oldenburg B, Rampton D, Schroeder O, Stein J, Travis S, Van Assche G. "Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases." Inflamm Bowel Dis. 2007 Dec;13(12):1545-53. [PubMed] [pdf]

Bartel G, Weiss I, Turetschek K, Schima W, Püspök A, Waldhoer T, Gasche C. "Ingested matter affects intestinal lesions in Crohn's disease." Inflamm Bowel Dis. 2007 Oct 11; [PubMed] [pdf]

David T. Rubin, Marcia R. Cruz-Correa, Christoph Gasche, Jeremy R. Jass, Gary R. Lichtenstein, Elizabeth A. Montgomery,PRobert H. Riddell, Matthew D. Rutter, Thomas A. Ullman, Fernando S. Velayos and Steven Itzkowitz. "Colorectal Cancer Prevention in Inflammatory Bowel Disease and the Role of 5-Aminosalicylic Acid: a Clinical Review and Update" Inflamm Bowel Dis 2007;13:000–000 [PubMed] [pdf]

Luciani MG, Campregher C, Gasche C. "Aspirin blocks Proliferation in Colon Cells by inducing a G1-Arrest and Apoptosis through Activation of the Checkpoint Kinase ATM" Carcinogenesis. 2007 Oct;28(10):2207-17. Epub 2007 May 17. [PubMed] [pdf]

Luciani MG, Campregher C, Fortune JM, Kunkel TA, Gasche C. "5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint" Gastroenterology. 2007 Jan;132(1):221-35. [PubMed] [pdf]


2006

Kulnigg S, Gasche C. "Systematic review: managing anaemia in Crohn's disease" Aliment Pharmacol Ther. 2006 Dec;24(11-12):1507-23. [PubMed] [pdf]

Gasche C, Kulnigg S. "Intravenous Iron in Inflammatory Bowel Disease" Semin Hematol. 2006 Oct; 34(6) S18-S22. [Abstract] [pdf]


2005

Boland CR, Luciani MG, Gasche C, Goel A. "Infection, inflammation, and gastrointestinal cancer" Gut. 2005 Sep;54(9):1321-31. [PubMed] [pdf]

Gasche C, Goel A, Natarajan L, Boland CR. "Mesalazine improves replication fidelity in cultured colorectal cells" Cancer Res. 2005 May 15;65(10):3993-7. [PubMed] [pdf]


2004

Gasche C, Lomer M C E, Cavill I, Weiss G. "Iron, anaemia, and inflammatory bowel diseases" Gut 2004;53:1190–1197. [PubMed] [pdf]


2003

Gasche C, Chang CL, Natarajan L, Goel A, Rhees J, Young DJ, Arnold CN, Boland CR.  "Identification of frame-shift intermediate mutant cells" Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1914-9. [PubMed[pdf]

2000

Gasche C. "Anemia in IBD: The Overlooked Villain" Inflamm Bowel Dis. 2000 May;6(2):142-150; discussion 151. [PubMed[pdf]

Gasche C, Scholmerich J, Brynskov J, D'Haens G, Hanauer SB, Irvine EJ, Jewell DP, Rachmilewitz D, Sachar DB, Sandborn WJ, Sutherland LR. "A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998." Inflamm Bowel Dis. 2000 Feb;6(1):8-15. [PubMed] [pdf]

1997

Gasche C, Dejaco C, Waldhoer T, Tillinger W, Reinisch W, Fueger GF, Gangl A, Lochs H. "Intravenous iron and erythropoietin for anemia associated with Crohn disease. A randomized, controlled trial." Ann Intern Med. 1997 May 15;126(10):782-7. [PubMed] [pdf]