Publications

Publications

For the original list (537 publications), please visit PubMed (http://www.ncbi.nlm.nih.gov/pubmed?term=lubec-g[Author])
Find peptide submissions of our lab at UniProtKB (http://www.uniprot.org/uniprot/?query=lubec)

Updated May 24th, 2013

Heo S, Csaszar E, Jung G, Beuk T, Höger H, Lubec G.
Hippocampal levels and activity of the sodium/potassium transporting ATPase subunit alpha-3 (AT1A3) are paralleling memory training in the multiple T-Maze in the C57BL/6J mouse.
Neurochem Int. 2012 Oct;61(5):702-12. doi: 10.1016/j.neuint.2012.07.006. Epub 2012 Jul 14. PMID: 22797008.

Bae N, Lödl M, Pollak A, Lubec G.
Mass spectrometrical analysis of bilin-binding protein from the wing of Hebomoia glaucippe (Linnaeus, 1758) (Lepidoptera: Pieridae).
Electrophoresis. 2012 Jul;33(12):1787-94. doi:10.1002/elps.201100569. PMID: 22740467.

Lee JC, Kang SU, Jeon Y, Park JW, You JS, Ha SW, Bae N, Lubec G, Kwon SH, Lee JS, Cho EJ, Han JW.
Protein L-isoaspartyl methyltransferase regulates p53 activity.
Nat Commun. 2012 Jun 26;3:927. doi: 10.1038/ncomms1933. PMID:22735455.

Rosner M, Schipany K, Shanmugasundaram B, Lubec G, Hengstschläger M.
Amniotic fluid stem cells: future perspectives.
Stem Cells Int. 2012;2012:741810. doi: 10.1155/2012/741810. PubMed Central PMCID: PMC3375114. Epub 2012 Jun 6. PMID: 22719774

Föcking M, Chen WQ, Dicker P, Dunn MJ, Lubec G, Cotter DR.
Proteomic analysis of human hippocampus shows differential protein expression in the different hippocampal subfields.
Proteomics. 2012 Aug;12(15-16):2477-81. doi: 10.1002/pmic.201200031. PMID: 22707153.

Birner-Gruenberger R, Darnhofer B, Chen WQ, Monje FJ, Lubec G.
Proteomic characterisation of the abdominal ganglion of Aplysia californica -A protein resource for neuroscience.
Proteomics. 2012 Aug;12(15-16):2482-6. doi: 10.1002/pmic.201100641. Epub 2012 Jul 23. PMID: 22696492.

Haschemi A, Kosma P, Gille L, Evans CR, Burant CF, Starkl P, Knapp B, Haas R, Schmid JA, Jandl C, Amir S, Lubec G, Park J,  Esterbauer H, Bilban M, Brizuela L, Pospisilik JA, Otterbein LE, Wagner O.
The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism.
Cell Metab. 2012 Jun 6;15(6):813-26. doi: 10.1016/j.cmet.2012.04.023. PMID: 22682222.

Bae N, Yang JW, Sitte H, Pollak A, Marquez J, Lubec G.
An electrophoretic approach to screen for glutamine deamidation.
Anal Biochem. 2012 Sep 1;428(1):1-3. doi: 10.1016/j.ab.2012.05.016. Epub 2012 May 26. PMID: 22640603.

Sase S, Khan D, Sialana F, Höger H, Russo-Schlaff N, Lubec G.
Modafinil improves performance in the multiple T-Maze and modifies GluR1, GluR2, D2 and NR1 receptor complex levels in the C57BL/6J mouse.
Amino Acids. 2012 Dec;43(6):2285-92. doi: 10.1007/s00726-012-1306-y. Epub 2012 May 22. PMID: 22614872.

Wan J, Csaszar E, Chen WQ, Li K, Lubec G.
Proteins from Avastin® (bevacizumab) Show Tyrosine Nitrations for which the Consequences Are Completely Unclear.
PLoS One. 2012;7(4):e34511. doi: 10.1371/journal.pone.0034511. Epub 2012 Apr 16. PMID: 22523550.

Lubec G.
Introduction to the special section on proteins and proteomics.
Hippocampus. 2012 May;22(5):927-8. doi: 10.1002/hipo.22022. Epub 2012 Apr 10. PMID: 22488714.

Tiboldi A, Lentini A, Provenzano B, Tabolacci C, Höger H, Beninati S, Lubec G.
Hippocampal polyamine levels and transglutaminase activity are paralleling spatial memory retrieval in the C57BL/6J mouse.
Hippocampus. 2012 May;22(5):1068-74. doi: 10.1002/hipo.22016. Epub 2012 Mar 30. PMID: 22467251.

Li K, Müller I, Patil S, Höger H, Pollak A, Russo-Schlaff N, Lubec G, Li L.
Strain-independent global effect of hippocampal proteins in mice trained in the Morris water maze.
Amino Acids. 2012 Oct;43(4):1739-49. Epub 2012 Mar 9. PMID: 22402595.

Falsafi SK, Deli A, Höger H, Pollak A, Lubec G.
Scopolamine Administration Modulates Muscarinic, Nicotinic and NMDA Receptor Systems.
PLoS One. 2012;7(2):e32082. doi: 10.1371/journal.pone.0032082. Epub 2012 Feb 23. PMID: 22384146

Ghafari M, Höger H, Keihan Falsafi S, Russo-Schlaff N, Pollak A, Lubec G.
Mass Spectrometrical Identification of Hippocampal NMDA Receptor Subunits NR1, NR2A-D and Five Novel Phosphorylation Sites on NR2A and NR2B.
J Proteome Res. 2012 Mar 2;11(3):1891-6. doi: 10.1021/pr201099u. Epub 2012 Feb 15. PMID:22335236

Deli A, Schipany K, Rosner M, Höger H, Pollak A, Li L, Hengstschläger M, Lubec G.
Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice.
Behav Brain Res. 2012 Apr 15;229(2):320-4. doi: 10.1016/j.bbr.2012.01.017. Epub 2012 Jan 24. PMID: 22306200.

Falsafi SK, Ghafari M, Pollak A, Höger H, Lubec G.
Hippocampal AMPA-type receptor complexes containing GluR3 and GluR4 are paralleling training in the Multiple T-Maze.
Neurochem Int. 2012 Mar;60(4):425-30. doi: 10.1016/j.neuint.2012.01.005. Epub 2012 Jan 18. PMID: 22269807.

Chen WQ, Heymann G, Kursula P, Rosner M, Hengstschläger M, Huppertz H, Lubec G.
Effects of gigapascal level pressure on protein structure and function.
J Phys Chem B. 2012 Jan 26;116(3):1100-10. doi: 10.1021/jp207864c. Epub 2012 Jan 13. PMID: 22242786.

Wu Y, Wu M, Zhang Y, Li W, Gao Y, Li Z, Wang Z, Lubec G, Zhang C.
Lyophilization is suitable for storage and shipment of fresh tissue samples without altering RNA and protein levels stored at room temperature.
Amino Acids. 2012 Sep;43(3):1383-8. doi: 10.1007/s00726-011-1212-8. Epub 2012 Jan 4. PMID: 22215254

Monje FJ, Birner-Grünberger R, Hüttinger B, Divisch I, Pollak DD, Lubec G.
Proteomics reveals selective regulation of proteins in response to memory-related serotonin stimulation in Aplysia californica ganglia.
Proteomics. 2012 Feb;12(3):490-9. doi: 10.1002/pmic.201100418. Epub 2012 Jan 13. PMID: 22162403

Heo S, Jung G, Beuk T, Höger H, Lubec G.
Hippocampal glutamate transporter 1 (GLT-1) complex levels are paralleling memory training in the Multiple T-Maze in C57BL/6J mice.
Brain Struct Funct. 2012 Apr;217(2):363-78. doi: 10.1007/s00429-011-0362-5.Epub 2011 Nov 24. PMID: 22113856

Rosner M, Schipany K, Gundacker C, Shanmugasundaram B, Li K, Fuchs C, Lubec G, Hengstschläger M.
Renal differentiation of amniotic fluid stem cells: perspectives for clinical application and for studies on specific human genetic
diseases.
Eur J Clin Invest. 2012 Jun;42(6):677-84. doi: 10.1111/j.1365-2362.2011.02622.x. Epub 2011 Nov 8.  Review. PMID: 22060053

Sase A, Khan D, Höger H, Lubec G.
Intraperitoneal injection of saline modulates hippocampal brain receptor complex levels but does not impair performance in the Morris Water Maze.
Amino Acids. 2012 Aug;43(2):783-92. doi: 10.1007/s00726-011-1130-9. Epub 2011 Nov 2. PMID: 22045385.

Monje FJ, Kim EJ, Pollak DD, Cabatic M, Li L, Baston A, Lubec G.
Focal Adhesion Kinase Regulates Neuronal Growth, Synaptic Plasticity and Hippocampus-Dependent Spatial Learning and Memory.
Neurosignals. 2012;20(1):1-14. doi: 10.1002/pmic.201100418. Epub 2011 Sep 23. PMID: 22162403

Bae N, Lödl M, Pollak A, Lubec G.
Mass spectrometrical analysis of cuticular proteins from the wing of Hebemoia glaucippe (Linnaeus, 1758) (Lepidoptera:
Pieridae).
J Proteomics. 2011 Dec 21;75(2):517-31. doi: 10.1016/j.jprot.2011.08.017. Epub 2011 Aug 28. PMID: 21903182.

Li L, Boddul SV, Patil SS, Zheng JF, An G, Höger H, Lubec G.
Proteins linked to extinction in contextual fear conditioning in the C57BL/6J mouse.
Proteomics. 2011 Sep;11(18):3706-24. doi: 10.1002/pmic.201000444. Epub 2011 Aug 22. PMID: 21770032. 

Bae N, Pollak A, Lubec G.
Proteins from Erwinia asparaginase Erwinase® and E. coli asparaginase 2 MEDAC® for treatment of human leukemia, show a multitude of modifications for which the consequences are completely unclear.
Electrophoresis. 2011 Jul;32(14):1824-8. doi: 10.1002/elps.201100117. PMID: 21769889.

Ghafari M, Falsafi SK, Hoeger H, Lubec G.
Hippocampal levels of GluR1 and GluR2 complexes are modulated by training in the multiple T-Maze in C57BL/6J mice.
Brain Struct Funct. 2012 Apr;217(2):353-62. doi: 10.1007/s00429-011-0335-8. Epub 2011 Jun 22. PMID: 21695503.

Azizi AA, Li L, Ströbel T, Chen WQ, Slavc I, Lubec G.
Identification of c-myc-dependent proteins in the medulloblastoma cell line D425Med.
Amino Acids. 2012 Jun;42(6):2149-63. doi: 10.1007/s00726-011-0953-8. Epub 2011 Jun 12. PMID: 21667264.

Winding C, Sun Y, Höger H, Bubna-Littitz H, Pollak A, Schmidt P, Lubec G.
Serine/threonine-protein phosphatase 1 α levels are paralleling olfactory memory formation in the CD1 mouse.
Electrophoresis. 2011 Jun;32(13):1675-83. doi: 10.1002/elps.201000615. Epub 2011 Jun 6. PMID: 21647921.

Patil SS, Li K, Heo S, Höger H, Lubec G.
Proteins linked to spatial memory formation of CD1 mice in the multiple T-maze.
Hippocampus. 2012 May;22(5):1075-86. doi: 10.1002/hipo.20956. Epub 2011 May 26. PMID: 21618641.

 Kang SU, Heo S, Lubec G.
Mass spectrometric analysis of GABA(A) receptor subtypes and phosphorylations from mouse hippocampus.
Proteomics. 2011 Jun;11(11):2171-81. doi: 10.1002/pmic.201000374. Epub 2011 May 2. PMID: 21538884.

Ghafari M, Patil SS, Höger H, Pollak A, Lubec G.
NMDA-complexes linked to spatial memory performance in the Barnes maze in CD1 mice.
Behav Brain Res. 2011 Aug;221(1):142-8. doi: 10.1016/j.bbr.2011.02.042. Epub 2011 Mar 4. PMID: 21377497.

Whittle N, Li L, Chen WQ, Yang JW, Sartori SB, Lubec G, Singewald N.
Changes in brain protein expression are linked to magnesium restriction-induced depression-like behavior.
Amino Acids. 2011 Apr;40(4):1231-48. doi: 10.1007/s00726-010-0758-1. Epub 2011 Feb 11. PMID: 21312047.

Kang SU, Lubec G.
Determination of in-gel protein concentration by a ninhydrin-based method.
Proteomics. 2011 Feb;11(3):481-4. doi:10.1002/pmic.201000388. Epub 2011 Jan 3. PMID: 21268276.

Sun Y, Dierssen M, Toran N, Pollak DD, Chen WQ, Lubec G.
A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain.
J Proteomics. 2011 Apr 1;74(4):547-57. doi: 10.1016/j.jprot.2011.01.009. Epub 2011 Jan 22. PMID: 21262400.

Monje FJ, Kim EJ, Cabatic M, Lubec G, Herkner KR, Pollak DD.
A role for glucocorticoid-signaling in depression-like behavior of gastrin-releasing peptide recteptor knock-out mice.
Ann Med. 2011 Aug;43(5):389-402. doi: 10.3109/07853890.2010.538716. Epub 2011 Jan 24. PMID: 21254899.

Sun Y, Monje FJ, Pollak DD, Lubec G.
A first partial Aplysia californica proteome.
Amino Acids. 2011 Oct;41(4):955-68. doi: 10.1007/s00726-010-0795-9. Epub 2010 Nov 11. PMID: 21069399.

Heo S, Lubec G.
Generation and characterization of a specific polyclonal antibody against the mouse serotonin receptor 1A: A state-of-the-art recommendation on how to characterize antibody specificity.
Electrophoresis. 2010 Dec;31(23-24):3789-96. doi: 10.1002/elps.201000374. PMID: 21064142.

Nuwal T, Heo S, Lubec G, Buchner E.
Mass Spectrometric Analysis of Synapsinsin Drosophila melanogaster and Identification of Novel Phosphorylation Sites.
J Proteome Res. 2011 Feb 4;10(2):541-50. doi: 10.1021/pr100746s. Epub 2010 Nov 16. PMID: 21028912.

Whittle N, Hauschild M, Lubec G, Holmes A, Singewald N.
Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction.
J Neurosci. 2010 Oct 13;30(41):13586-96. doi: 10.1523/JNEUROSCI.0849-10.2010. PMID: 20943900.

Köfeler HC, Tiboldi A, Hoeger H, Lubec G.
Hippocampal lipids linked to spatial memory in the C57Bl/6j mouse.
Neurochem Int. 2010 Dec;57(8):935-9. doi: 10.1016/j.neuint.2010.09.013. Epub 2010 Oct 7. PMID: 20933031.

Heo S, Patil SS, Jung G, Höger H, Lubec G.
A serotonin receptor 1A containing complex in hippocampus of PWD/PhJ mice is linked to training effects in the Barnes maze.
Behav Brain Res. 2011 Jan 1;216(1):389-95. doi: 10.1016/j.bbr.2010.08.018. Epub 2010 Aug 20. PMID: 20728472.

Burgos M, Fradejas N, Calvo S, Kang SU, Tranque P, Lubec G.
A proteomic analysis of PKCepsilon targets in astrocytes: implications for astrogliosis.
Amino Acids. 2011 Feb;40(2):641-51. doi: 10.1007/s00726-010-0691-3. Epub 2010 Jul 17. PMID: 20640460.

 Siegel N, Rosner M, Unbekandt M, Fuchs C, Slabina N, Dolznig H, Davies JA, Lubec G, Hengstschläger M.
Contribution of human amniotic fluid stem cells to renal tissue formation depends on mTOR.
Hum Mol Genet. 2010 Sep 1;19(17):3320-31. doi: 10.1093/hmg/ddq236. Epub 2010 Jun 11. PMID: 20542987.

Heo S, Kang SU, Oehler R, Pollak A, Lubec G.
Mass spectrometrical analysis of the mitochondrial carrier Aralar1 from mouse hippocampus.
Electrophoresis. 2010 Jun;31(11):1813-21. doi: 10.1002/elps.200900727. PMID: 20506418.

 Chen WQ, Salmazo A, Myllykoski M, Sjöblom B, Bidlingmaier M, Pollak A, Baumgärtel P, Djinovic-Carugo K, Kursula P, Lubec G.
Purification of recombinant growth hormone by clear native gels for conformational analyses: preservation of conformation and receptor binding.
Amino Acids. 2010 Aug;39(3):859-69. doi: 10.1007/s00726-010-0542-2. Epub 2010 Mar 19. PMID: 20238132.

 Li L, Mauric V, Zheng JF, Kang SU, Patil S, Höger H, Lubec G.
Olfactory bulb proteins linked to olfactory memory in C57BL/6J mice.
Amino Acids. 2010 Aug;39(3):871-86. doi: 10.1007/s00726-010-0543-1. Epub 2010 Mar 12. PMID: 20225135.

Afjehi-Sadat L, Brejnikow M, Kang SU, Vishwanath V, Walder N, Herkner K, Redl H, Lubec G.
Differential protein levels and post-translational modifications in spinal cord injury of the rat.
J Proteome Res. 2010 Mar 5;9(3):1591-7. doi: 10.1021/pr901049a. PMID: 20141154.

Patil SS, Schlick F, Höger H, Lubec G.
Linkage of hippocampal proteins to spatial memory formation and strain-dependence in Apodemus sylvaticus, C57BL/6J and PWD/PhJ mice.
Neurochem Int. 2010 Feb;56(3):522-7. doi: 10.1016/j.neuint.2009.12.013. Epub 2009 Dec 30. PubMed PMID: 20036702.

Chen WQ, Priewalder H, John JP, Lubec G.
Silk cocoon of Bombyx mori: proteins and posttranslational modifications--heavy phosphorylation and evidence for lysine-mediated cross links.
Proteomics. 2010 Feb;10(3):369-79. doi: 10.1002/pmic.200900624. PMID: 20029844.

Chen WQ, Graf C, Zimmel D, Rovina P, Krapfenbauer K, Jaritz M, Parker PJ, Lubec G, Bornancin F.
Ceramide kinase profiling by mass spectrometry reveals a conserved phosphorylation pattern downstream of the catalytic site.
J Proteome Res. 2010 Jan;9(1):420-9. doi: 10.1021/pr900763z. PMID: 19899769.

Patil SS, Schlick F, Höger H, Lubec G.
Involvement of individual hippocampal signaling protein levels in spatial memory formation is strain-dependent.
Amino Acids. 2010 Jun;39(1):75-87. doi: 10.1007/s00726-009-0379-8. Epub 2009 Nov 5. Erratum in: Amino Acids. 2010 Jul;39(2):617-8. PMID: 19890699.

Majava V, Wang C, Myllykoski M, Kangas SM, Kang SU, Hayashi N, Baumgärtel P, Heape AM, Lubec G, Kursula P.
Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule.
Amino Acids. 2010 Jun;39(1):59-71.  PubMed PMID: 19855925.

Chen WQ, Siegel N, Li L, Pollak A, Hengstschläger M, Lubec G.
Variations of protein levels in human amniotic fluid stem cells CD117/2 over passages 5-25.
J Proteome Res. 2009 Nov;8(11):5285-95. PubMed PMID: 19791749.

Kang SU, Fuchs K, Sieghart W, Pollak A, Csaszar E, Lubec G.
Gel-based mass spectrometric analysis of a strongly hydrophobic GABAA-receptor subunit containing four transmembrane domains.
Nat Protoc. 2009;4(7):1093-102. PubMed PMID: 19707190.

John JP, Pollak A, Lubec G.
Complete sequencing and oxidative modification of manganese superoxide dismutase in medulloblastoma cells.
Electrophoresis. 2009 Sep;30(17):3006-16. PubMed PMID: 19676086.

Zheng JF, Patil SS, Chen WQ, An W, He JQ, Höger H, Lubec G.
Hippocampal protein levels related to spatial memory are different in the Barnes maze and in the multiple T-maze.
J Proteome Res. 2009 Oct;8(10):4479-86. PubMed PMID: 19650667.

Suder P, Bodzon-Kulakowska A, Mak P, Bierczynska-Krzysik A, Daszykowski M, Walczak B, Lubec G, Kotlinska JH, Silberring J.
The proteomic analysis of primary cortical astrocyte cell culture after morphine administration.
J Proteome Res. 2009 Oct;8(10):4633-40. PubMed PMID: 19642706.

Kang SU, Zhang M, Burgos M, Lubec G.
Mass spectrometrical characterisation of mouse and rat synapsin isoforms 2a and 2b.
Amino Acids. 2010 Apr;38(4):1131-43. PubMed PMID: 19609639.

Li L, Whittle N, Klug S, Chen WQ, Singewald N, Toth M, Lubec G.
Serotonin(1A)-receptor-dependent signaling proteins in mouse hippocampus.
Neuropharmacology. 2009 Oct-Nov;57(5-6):556-66. PubMed PMID: 19607848.

Kang SU, Lubec G.
Complete sequencing of GABAA receptor subunit beta 3 by a rapid technique following in-gel digestion of the protein.
Electrophoresis. 2009 Jun;30(12):2159-67. PubMed PMID: 19582715.

Jüch M, Smalla KH, Kähne T, Lubec G, Tischmeyer W, Gundelfinger ED, Engelmann M.
Congenital lack of nNOS impairs long-term social recognition memory and alters the olfactory bulb proteome.
Neurobiol Learn Mem. 2009 Nov;92(4):469-84. PubMed PMID: 19531381.

Ahmed KE, Chen WQ, John JP, Kang SU, Lubec G.
Complete sequencing of the recombinant granulocyte-colony stimulating factor (filgrastim) and detection of biotinylation by mass spectrometry.
Amino Acids. 2010 Apr;38(4):1043-9. PubMed PMID: 19526310.

Sunyer B, An G, Kang SU, Höger H, Lubec G.
Strain-dependent hippocampal protein levels of GABA(B)-receptor subunit 2 and NMDA-receptor subunit 1.
Neurochem Int. 2009 Sep;55(4):253-6. PubMed PMID: 19524116.

Sunyer B, Diao WF, Kang SU, An G, Boddul S, Lubec G.
Cognitive enhancement by SGS742 in OF1 mice is linked to specific hippocampal protein expression.
J Proteome Res. 2008 Dec;7(12):5237-53. PubMed PMID: 19367722.

Haikarainen T, Chen WQ, Lubec G, Kursula P.
Structure, modifications and ligand-binding properties of rat profilin 2a.
Acta Crystallogr D Biol Crystallogr. 2009 Apr;65(Pt 4):303-11. PubMed PMID: 19307711.

Bodzon-Kulakowska A, Suder P, Mak P, Bierczynska-Krzysik A, Lubec G, Walczak B, Kotlinska J, Silberring J.
Proteomic analysis of striatal neuronal cell cultures after morphine administration.
J Sep Sci. 2009 Apr;32(8):1200-10. PubMed PMID: 19296477.

Baer AS, Syed YA, Kang SU, Mitteregger D, Vig R, Ffrench-Constant C, Franklin RJ, Altmann F, Lubec G, Kotter MR.
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling.
Brain. 2009 Feb;132(Pt 2):465-81. PubMed PMID: 19208690; PubMed Central PMCID: PMC2640211.

Gruber-Olipitz M, Ströbel T, Kang SU, John JP, Grotzer MA, Slavc I, Lubec G.
Neurotrophin 3/TrkC-regulated proteins in the human medulloblastoma cell line DAOY.
Electrophoresis. 2009 Feb;30(3):540-9. PubMed PMID: 19156760.

Myung JK, Shim KS, Li L, Höger H, Lubec G.
Developmental brain protein level changes in the C57BL/6J mouse.
J Proteome Res. 2009 Mar;8(3):1207-19. PubMed PMID: 19154180.

John JP, Sunyer B, Höger H, Pollak A, Lubec G.
Hippocampal synapsin isoform levels are linked to spatial memory enhancement by SGS742.
Hippocampus. 2009 Aug;19(8):731-8. PubMed PMID: 19140176.

Patil SS, Sunyer B, Höger H, Lubec G.
Evaluation of spatial memory of C57BL/6J and CD1 mice in the Barnes maze, the Multiple T-maze and in the Morris water maze.
Behav Brain Res. 2009 Mar 2;198(1):58-68. PubMed PMID: 19022298.

Whittle N, Lubec G, Singewald N.
Zinc deficiency induces enhanced depression-like behaviour and altered limbic activation reversed by antidepressant treatment in mice. Amino Acids.
2009 Jan;36(1):147-58. PubMed PMID: 18975044.

Pabst M, Kolarich D, Pöltl G, Dalik T, Lubec G, Hofinger A, Altmann F.
Comparison of fluorescent labels for oligosaccharides and introduction of a new postlabeling purification method.
Anal Biochem. 2009 Jan 15;384(2):263-73. PubMed PMID: 18940176.

Sunyer B, Shim KS, An G, Höger H, Lubec G.
Hippocampal levels of phosphorylated protein kinase A (phosphor-S96) are linked to spatial memory enhancement by SGS742.
Hippocampus. 2009 Jan;19(1):90-8. PubMed PMID: 18727045.

Majava V, Löytynoja N, Chen WQ, Lubec G, Kursula P.
Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2.
FEBS J. 2008 Sep;275(18):4583-96. PubMed PMID: 18699782.

Azizi AA, Kang SU, Freilinger A, Gruber-Olipitz M, Chen WQ, Yang JW, Hengstschläger M, Slavc I, Lubec G.
Mitosis-dependent protein expression in neuroblastoma cell line N1E-115.
J Proteome Res. 2008 Aug;7(8):3412-22. PubMed PMID: 18582092.

Kang SU, Fuchs K, Sieghart W, Lubec G.
Gel-based mass spectrometric analysis of recombinant GABA(A) receptor subunits representing strongly hydrophobic
transmembrane proteins.
J Proteome Res. 2008 Aug;7(8):3498-506. PubMed PMID: 18563923.

Diao WF, Afjehi-Sadat L, Chen WQ, Höger J, Höger H, Pollak A, Lubec G.
Hippocampal levels of gamma-enolase, C-1-tetrahydrofolate synthase and serotransferrin fluctuate over the estrous cycle in the rat.
Neuroscience. 2008 Jun 26;154(3):1009-20. PubMed PMID: 18511206.

Sunyer B, Diao W, Lubec G.
The role of post-translational modifications for learning and memory formation.
Electrophoresis. 2008 Jun;29(12):2593-602. Review. PubMed PMID: 18494028.

Weitzdörfer R, Höger H, Shim KS, Cekici L, Pollak A, Lubec G. Changes of hippocampal signaling protein levels during postnatal brain development in the rat.
Hippocampus. 2008;18(8):807-13. PubMed PMID: 18493952.

Kirchner L, Chen WQ, Afjehi-Sadat L, Viidik A, Skalicky M, Höger H, Lubec G.
Hippocampal metabolic proteins are modulated in voluntary and treadmill exercise rats.
Exp Neurol. 2008 Jul;212(1):145-51. PubMed PMID: 18455160.

Höger J, Patterson D, Höger H, Shim KS, Bubna-Littitz H, Lubec G.
Mice transgenic for reduced folate carrier: an animal model of Down syndrome?
Amino Acids. 2009 Feb;36(2):349-57. PubMed PMID: 18414976.

Weitzdörfer R, Höger H, Burda G, Pollak A, Lubec G.
Differences in hippocampal protein expression at 3 days, 3 weeks, and 3 months following induction of perinatal asphyxia in the rat.
J Proteome Res. 2008 May;7(5):1945-52. PubMed PMID: 18355016.

Syed YA, Baer AS, Lubec G, Hoeger H, Widhalm G, Kotter MR.
Inhibition of oligodendrocyte precursor cell differentiation by myelin-associated proteins.
Neurosurg Focus. 2008;24(3-4):E5. PubMed PMID: 18341408.

Gruber-Olipitz M, Ströbel T, Chen WQ, Grotzer MA, Quehenberger F, Slavc I, Lubec G.
Synthesis, chaperoning, and metabolism of proteins are regulated by NT-3/TrkC signaling in the medulloblastoma cell line DAOY.
J Proteome Res. 2008 May;7(5):1932-44. PubMed PMID: 18336001.

Sunyer B, Shim KS, Höger H, Lubec G.
The cognitive enhancer SGS742 does not involve major known signaling cascades in OF1 mice.
Neurochem Res. 2008 Jul;33(7):1384-92. PubMed PMID: 18322794.

Patil SS, Sunyer B, Höger H, Lubec G.
Apodemus sylvaticus (LOXT) is a suitable mouse strain for testing spatial memory retention in the Morris water
maze.
Neurobiol Learn Mem. 2008 May;89(4):552-9. PubMed PMID: 18242105.

Chen WQ, Diao WF, Viidik A, Skalicky M, Höger H, Lubec G.
Modulation of the hippocampal protein machinery in voluntary and treadmill exercising rats.
Biochim Biophys Acta. 2008 Mar;1784(3):555-62. PubMed PMID: 18230368.

Cheon MS, Dierssen M, Kim SH, Lubec G.
Protein expression of BACE1, BACE2 and APP in Down syndrome brains.
Amino Acids. 2008 Aug;35(2):339-43. PubMed PMID: 18163181.

John JP, Oh JE, Pollak A, Lubec G.
Identification and characterisation of arsenite (+3 Oxidation State) methyltransferase (AS3MT) in mouse neuroblastoma cell line N1E-115.
Amino Acids. 2008 Aug;35(2):355-8. PubMed PMID: 18157586.

Rendić D, Wilson IB, Lubec G, Gutternigg M, Altmann F, Léonard R.
Adaptation of the "in-gel release method" to N-glycome analysis of low-milligram amounts of
material.
Electrophoresis. 2007 Dec;28(23):4484-92. PubMed PMID: 18041037.

Diao WF, Chen WQ, Höger H, Pollak A, Lubec G.
Fluctuations of hippocampal neuronal protein levels over the estrous cycle in the rat.
Neurochem Int. 2008 May;52(6):1002-11. PubMed PMID: 18036704.

Whittle N, Sartori SB, Dierssen M, Lubec G, Singewald N.
Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development.
Pediatrics. 2007 Dec;120(6):e1465-71. PubMed PMID: 17998315.

Chen WQ, Viidik A, Skalicky M, Höger H, Lubec G.
Hippocampal signaling cascades are modulated in voluntary and treadmill exercise rats.
Electrophoresis. 2007 Dec;28(23):4392-400. PubMed PMID: 17963288.

Afjehi-Sadat L, Lubec G.
Identification of enzymes and activity from two-dimensional gel electrophoresis.
Nat Protoc. 2007;2(10):2318-24. PubMed PMID: 17947972.

Shin JH, Guedj F, Delabar JM, Lubec G.
Dysregulation of growth factor receptor-bound protein 2 and fascin in hippocampus of mice polytransgenic for
chromosome 21 structures.
Hippocampus. 2007;17(12):1180-92. PubMed PMID: 17696169.

Sunyer B, Patil S, Frischer C, Hoeger H, Lubec G.
Strain-dependent effects of cognitive enhancers in the mouse.
Amino Acids. 2008 Apr;34(3):485-95. PubMed PMID: 17690951.

Lubec G, Afjehi-Sadat L.
Limitations and pitfalls in protein identification by mass spectrometry.
Chem Rev. 2007 Aug;107(8):3568-84. Review. PubMed PMID: 17645314.

John JP, Chen WQ, Pollak A, Lubec G.
Mass spectrometric studies on mouse hippocampal synapsins Ia, IIa, and IIb and identification of a novel phosphorylation site at serine-546.
J Proteome Res. 2007 Jul;6(7):2695-710. PubMed PMID: 17579389.

Chen WQ, Hoeger H, Diao WF, Pollak A, Lubec G.
Mass spectrometrical characterization of NDRG2 protein (N-myc-downstream regulated gene 2) and description of two novel phosphorylation sites.
Neurochem Res. 2007 Nov;32(11):1969-77. PubMed PMID: 17570058.

Diao WF, Höger H, Chen WQ, Pollak A, Lubec G.
Hippocampal signaling protein levels are different in early and late metestrus in the rat.
Biochim Biophys Acta. 2007 Aug;1774(8):1044-51. PubMed PMID: 17569602.

Oh JE, Freilinger A, Gelpi E, Pollak A, Hengstschläger M, Lubec G.
Proteins involved in neuronal differentiation of neuroblastoma cell line N1E-115.
Electrophoresis. 2007 Jun;28(12):2009-17. PubMed PMID: 17503409.

Myung JK, Frischer T, Afjehi-Sadat L, Pollak A, Lubec G.
Mass spectrometrical analysis of the processed metastasis-inducing anterior gradient protein 2 homolog reveals 100% sequence coverage.
Amino Acids. 2008 Aug;35(2):485-94. PubMed PMID: 17497304.

Rosner M, Freilinger A, Hanneder M, Fujita N, Lubec G, Tsuruo T, Hengstschläger M.
p27Kip1 localization depends on the tumor suppressor protein tuberin.
Hum Mol Genet. 2007 Jul 1;16(13):1541-56. PubMed PMID: 17470459.

Sunyer B, Patil S, Frischer C, Höger H, Selcher J, Brannath W, Lubec G.
Strain-dependent effects of SGS742 in the mouse.
Behav Brain Res. 2007 Jul 19;181(1):64-75. PubMed PMID: 17467069.

Diao WF, Höger H, Chen WQ, Pollak A, Lubec G.
Estrous-cycle-dependent hippocampal levels of signaling proteins.
Hippocampus. 2007;17(7):563-76. PubMed PMID: 17427236.

Chen WQ, Kang SU, Lubec G.
Protein profiling by the combination of two independent mass spectrometry techniques.
Nat Protoc. 2006;1(3):1446-52. PubMed PMID: 17406433.

Daszykowski M, Stanimirova I, Bodzon-Kulakowska A, Silberring J, Lubec G, Walczak B.
Start-to-end processing of two-dimensional gel electrophoretic images.
J Chromatogr A. 2007 Jul 27;1158(1-2):306-17. PubMed PMID: 17335835.

John JP, Pintsov O, Petter-Puchner A, Redl H, Pollak A, Chen WQ, Lubec G.
Nitric oxide and oxygen radical attack on GDP-dissociation inhibitor 2 (GDI-2) in spinal cord injury of the rat.
J Proteome Res. 2007 Apr;6(4):1500-9. PubMed PMID: 17315910.

Afjehi-Sadat L, Yang JW, Pollak A, Kim DW, Choi SY, Lubec G.
Structural and functional analysis of hypothetical proteins in mouse hippocampus from two-dimensional gel electrophoresis.
J Proteome Res. 2007 Feb;6(2):711-23. Erratum in: J Proteome Res. 2007 Apr;6(4):1615. PubMed PMID: 17269727.

Savaskan NE, Rocha L, Kotter MR, Baer A, Lubec G, van Meeteren LA, Kishi Y, Aoki J, Moolenaar WH, Nitsch R, Bräuer AU.
Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma.
Cell Mol Life Sci. 2007 Jan;64(2):230-43. PubMed PMID: 17192809.

Weitzdörfer R, Höger H, Pollak A, Lubec G.
Changes of hippocampal protein levels during postnatal brain development in the rat.
J Proteome Res. 2006 Nov;5(11):3205-12. PubMed PMID: 17081073.

Bierczynska-Krzysik A, Pradeep John JP, Silberring J, Kotlinska J, Dylag T, Cabatic M, Lubec G.
Proteomic analysis of rat cerebral cortex, hippocampus and striatum after exposure to morphine.
Int J Mol Med. 2006 Oct;18(4):775-84. PubMed PMID: 16964434.

Hamacher M, Apweiler R, Arnold G, Becker A, Blüggel M, Carrette O, Colvis C, Dunn MJ, Fröhlich T, Fountoulakis M, van Hall A, Herberg F, Ji J, Kretzschmar H, Lewczuk P, Lubec G, Marcus K, Martens L, Palacios Bustamante N, Park YM, Pennington SR, Robben J, Stühler K, Reidegeld KA, Riederer P, Rossier J, Sanchez JC, Schrader M, Stephan C, Tagle D, Thiele H, Wang J, Wiltfang J, Yoo JS, Zhang C, Klose J, Meyer HE.
HUPO Brain Proteome Project: summary of the pilot phase and introduction of a comprehensive data reprocessing strategy.
Proteomics. 2006 Sep;6(18):4890-8. Erratum in: Proteomics. 2006 Oct;6(20):5674. Ji, Juango [corrected to Ji, Jianguo]. PubMed PMID: 16927433.

Föcking M, Boersema PJ, O'Donoghue N, Lubec G, Pennington SR, Cotter DR, Dunn MJ.
2-D DIGE as a quantitative tool for investigating the HUPO Brain Proteome Project mouse series.
Proteomics. 2006 Sep;6(18):4914-31. PubMed PMID: 16927420.

Engidawork E, Afjehi-Sadat L, Yang JW, Slavc I, Lubec G.
Protein chemical identification and characterization of the human variants of far upstream element binding protein in medulloblastoma DAOY cell line.
Int J Oncol. 2006 Sep;29(3):721-36. PubMed PMID: 16865290.

Yang JW, Afjehi-Sadat L, Gelpi E, Kunze M, Höger H, Fleckner J, Berger J, Lubec G.
Proteome profiling in the rat Harderian gland.
J Proteome Res. 2006 Jul;5(7):1751-62. PubMed PMID: 16823983.

Pollak DD, John J, Hoeger H, Lubec G.
An integrated map of the murine hippocampal proteome based upon five mouse strains.
Electrophoresis. 2006 Jul;27(13):2787-98. PubMed PMID: 16817167.

Yang JW, Kang SU, Engidawork E, Rodrigo R, Felipo V, Lubec G.
Mass spectrometrical analysis of galectin proteins in primary rat cerebellar astrocytes.
Neurochem Res. 2006 Jul;31(7):945-55. PubMed PMID: 16804752.

Gruber-Olipitz M, Yang JW, Slavc I, Lubec G.
Nectin-like molecule 1 is a high abundance protein in cerebellar neurons.
Amino Acids. 2006 Jun;30(4):409-15. PubMed PMID: 16773244.

Shin JH, Krapfenbauer K, Lubec G.
Large-scale identification of cytosolic mouse brain proteins by chromatographic prefractionation.
Electrophoresis. 2006 Jul;27(13):2799-813. PubMed PMID: 16739224.

Gulesserian T, Engidawork E, Fountoulakis M, Lubec G.
Manifold decrease of sialic acid synthase in fetal Down syndrome brain.
Amino Acids. 2007 Jan;32(1):141-4. PubMed PMID: 16729195.

Freilinger A, Rosner M, Krupitza G, Nishino M, Lubec G, Korsmeyer SJ, Hengstschläger M.
Tuberin activates the proapoptotic molecule BAD.
Oncogene. 2006 Oct 19;25(49):6467-79. PubMed PMID: 16702951.

Pollak DD, John J, Bubna-Littitz H, Schneider A, Hoeger H, Lubec G.
Components of the protein quality control system are expressed in a strain-dependent manner in the mouse hippocampus.
Neurochem Int. 2006 Oct;49(5):500-7. PubMed PMID: 16678306.

Myung JK, Lubec G.
Use of solution-IEF-fractionation leads to separation of 2673 mouse brain proteins including 255 hydrophobic structures.
J Proteome Res. 2006 May;5(5):1267-75. PubMed PMID: 16674118.

John JP, Anrather D, Pollak A, Lubec G.
Mass spectrometrical verification of stomatin-like protein 2 (SLP-2) primary structure.
Proteins. 2006 Aug 1;64(2):543-51. PubMed PMID: 16671055.

Frischer T, Myung JK, Maurer G, Eichler I, Szepfalusi Z, Lubec G.
Possible dysregulation of chaperon and metabolic proteins in cystic fibrosis bronchial tissue.
Proteomics. 2006 Jun;6(11):3381-8. PubMed PMID: 16637013.

Shim KS, Rosner M, Freilinger A, Lubec G, Hengstschläger M.
Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells.
Exp Cell Res. 2006 Jul 15;312(12):2264-78. PubMed PMID: 16631738.

Shin JH, Krapfenbauer K, Lubec G.
Mass-spectrometrical analysis of proteins encoded on chromosome 21 in human fetal brain.
Amino Acids. 2006 Nov;31(4):435-47. PubMed PMID: 16622604.

Bierczynska-Krzysik A, Kang SU, Silberrring J, Lubec G.
Mass spectrometrical identification of brain proteins including highly insoluble and transmembrane proteins.
Neurochem Int. 2006 Aug;49(3):245-55. PubMed PMID: 16616972.

Lumbreras M, Baamonde C, Martínez-Cué C, Lubec G, Cairns N, Sallés J, Dierssen M, Flórez J.
Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease.
Amino Acids. 2006 Nov;31(4):449-56. PubMed PMID: 16583316.

Yang JW, Czech T, Felizardo M, Baumgartner C, Lubec G.
Aberrant expression of cytoskeleton proteins in hippocampus from patients with mesial temporal lobe epilepsy.
Amino Acids. 2006 Jun;30(4):477-93. PubMed PMID: 16583313.

Oh JE, Karlmark Raja K, Shin JH, Pollak A, Hengstschläger M, Lubec G.
Cytoskeleton changes following differentiation of N1E-115 neuroblastoma cell
line.
Amino Acids. 2006 Oct;31(3):289-98. PubMed PMID: 16547650.

Xixi E, Dimitraki P, Vougas K, Kossida S, Lubec G, Fountoulakis M.
Proteomic analysis of the mouse brain following protein enrichment by preparative electrophoresis.
Electrophoresis. 2006 Apr;27(7):1424-31. PubMed PMID: 16518779.

Pollak DD, John J, Scharl T, Leisch F, Schneider A, Hoeger H, Lubec G.
Strain-dependent regulation of neurotransmission and actin-remodelling proteins in the mouse hippocampus.
Genes Brain Behav. 2006 Mar;5(2):200-4. PubMed PMID: 16507010.

Oh JE, Karlmark KR, Shin J, Hengstschläger M, Lubec G.
Differentiation-dependent expression of hypothetical proteins in the neuroblastoma cell line N1E-115.
Proteins. 2006 May 15;63(3):671-80. PubMed PMID: 16425288.

Shin JH, Gulesserian T, Verger E, Delabar JM, Lubec G.
Protein dysregulation in mouse hippocampus polytransgenic for chromosome 21 structures in the Down Syndrome Critical Region.
J Proteome Res. 2006 Jan;5(1):44-53. PubMed PMID: 16396494.

Hepner F, Csaszar E, Roitinger E, Pollak A, Lubec G.
Massspectrometrical analysis of recombinant human growth hormone Norditropin reveals amino acid exchange at M14_V14 rhGH.
Proteomics. 2006 Feb;6(3):775-84. PubMed PMID: 16372270.

Azizi AA, Gelpi E, Yang JW, Rupp B, Godwin AK, Slater C, Slavc I, Lubec G.
Mass spectrometric identification of serine hydrolase OVCA2 in the medulloblastoma cell line DAOY.
Cancer Lett. 2006 Sep 28;241(2):235-49. PubMed PMID: 16368187.

Pollak DD, John J, Schneider A, Hoeger H, Lubec G.
Strain-dependent expression of signaling proteins in the mouse hippocampus.
Neuroscience. 2006;138(1):149-58. PubMed PMID: 16361066.

Ferrando-Miguel R, Rosner M, Freilinger A, Lubec G, Hengstschläger M.
Tuberin--a new molecular target in Alzheimer's disease?
Neurochem Res. 2005 Nov;30(11):1413-9. PubMed PMID: 16341938.

Hepner F, Myung JK, Ulfig N, Pollak A, Lubec G.
Detection of hypothetical proteins in human fetal perireticular nucleus.
J Proteome Res. 2005 Nov-Dec;4(6):2379-85. PubMed PMID: 16335990.

Afjehi-Sadat L, Engidawork E, Slavc I, Lubec G.
Comparative proteomic analysis of nucleic acid-binding proteins in ten human tumor cell lines.
Int J Oncol. 2006 Jan;28(1):173-90. PubMed PMID: 16327994.


101: Yang JW, Juranville JF, Höger H, Fountoulakis M, Lubec G. Molecular
diversity of rat brain proteins as revealed by proteomic analysis. Mol Divers.
2005;9(4):385-96. PubMed PMID: 16311815.


102: Karlmark KR, Freilinger A, Marton E, Rosner M, Lubec G, Hengstschläger M.
Activation of ectopic Oct-4 and Rex-1 promoters in human amniotic fluid cells.
Int J Mol Med. 2005 Dec;16(6):987-92. PubMed PMID: 16273276.


103: Lubec G, Afjehi-Sadat L, Yang JW, John JP. Searching for hypothetical
proteins: theory and practice based upon original data and literature. Prog
Neurobiol. 2005 Sep-Oct;77(1-2):90-127. Epub 2005 Nov 4. Review. PubMed PMID:
16271823.


104: Rosner M, Freilinger A, Lubec G, Hengstschläger M. The tuberous sclerosis
genes, TSC1 and TSC2, trigger different gene expression responses. Int J Oncol.
2005 Nov;27(5):1411-24. PubMed PMID: 16211238.


105: Pollak DD, Scharl T, Leisch F, Herkner K, Villar SR, Hoeger H, Lubec G.
Strain-dependent regulation of plasticity-related proteins in the mouse
hippocampus. Behav Brain Res. 2005 Dec 7;165(2):240-6. Epub 2005 Sep 12. PubMed
PMID: 16162363.


106: Yang JW, Czech T, Gelpi E, Lubec G. Extravasation of plasma proteins can
confound interpretation of proteomic studies of brain: a lesson from apo A-I in
mesial temporal lobe epilepsy. Brain Res Mol Brain Res. 2005 Oct 3;139(2):348-56.
PubMed PMID: 16095751.


107: Hengstschläger M, Rosner M, Fountoulakis M, Lubec G. The cellular response
to ectopic overexpression of the tuberous sclerosis genes, TSC1 and TSC2: a
proteomic approach. Int J Oncol. 2005 Sep;27(3):831-8. PubMed PMID: 16077935.


108: Gruber-Olipitz M, Yang JW, Stroebel T, Slavc I, Lubec G. The medulloblastoma
cell line DAOY but not eleven other tumor cell lines expresses minichromosome
maintenance protein 4. Cancer Lett. 2006 Jul 8;238(1):76-84. Epub 2005 Jul 26.
PubMed PMID: 16051427.


109: Oh JE, Karlmark KR, Shin JH, Pollak A, Freilinger A, Hengstschläger M, Lubec
G. Differentiation of neuroblastoma cell line N1E-115 involves several signaling
cascades. Neurochem Res. 2005 Mar;30(3):333-48. PubMed PMID: 16018577.


110: Garbis S, Lubec G, Fountoulakis M. Limitations of current proteomics
technologies. J Chromatogr A. 2005 Jun 3;1077(1):1-18. Review. PubMed PMID:
15988981.


111: Oh JE, Karlmark Raja K, Shin JH, Hengstschläger M, Pollak A, Lubec G. The
neuronal differentiation process involves a series of antioxidant proteins. Amino
Acids. 2005 Nov;29(3):273-82. Epub 2005 Jun 30. PubMed PMID: 15986180.


112: Shin JH, Krapfenbauer K, Lubec G. Column chromatographic prefractionation
leads to the detection of 543 different gene products in human fetal brain.
Electrophoresis. 2005 Jul;26(14):2759-78. PubMed PMID: 15966016.


113: Yang JW, Rodrigo R, Felipo V, Lubec G. Proteome analysis of primary neurons
and astrocytes from rat cerebellum. J Proteome Res. 2005 May-Jun;4(3):768-88.
PubMed PMID: 15952724.


114: Pollak DD, Herkner K, Hoeger H, Lubec G. Behavioral testing upregulates
pCaMKII, BDNF, PSD-95 and egr-1 in hippocampus of FVB/N mice. Behav Brain Res.
2005 Aug 30;163(1):128-35. PubMed PMID: 15927279.


115: Yang JW, Suder P, Silberring J, Lubec G. Proteome analysis of mouse primary
astrocytes. Neurochem Int. 2005 Aug;47(3):159-72. PubMed PMID: 15908045.


116: Hepner F, Pollak A, Ulfig N, Yae-Kyung M, Lubec G. Mass spectrometrical
analysis of human serine racemase in foetal brain. J Neural Transm. 2005
Jun;112(6):805-11. PubMed PMID: 15868395.


117: Shin JH, London J, Le Pecheur M, Weitzdoerfer R, Hoeger H, Lubec G. Proteome
analysis in hippocampus of mice overexpressing human Cu/Zn-superoxide dismutase
1. Neurochem Int. 2005 Jun;46(8):641-53. Epub 2005 Apr 7. PubMed PMID: 15863242.


118: Fountoulakis M, Tsangaris GT, Maris A, Lubec G. The rat brain hippocampus
proteome. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 May
5;819(1):115-29. PubMed PMID: 15797529.


119: Hepner F, Cszasar E, Roitinger E, Lubec G. Mass spectrometrical analysis of
recombinant human growth hormone (Genotropin(R)) reveals amino acid substitutions
in 2% of the expressed protein. Proteome Sci. 2005 Feb 11;3(1):1. PubMed PMID:
15707495; PubMed Central PMCID: PMC549540.


120: Tsangaris G, Weitzdörfer R, Pollak D, Lubec G, Fountoulakis M. The amniotic
fluid cell proteome. Electrophoresis. 2005 Mar;26(6):1168-73. PubMed PMID:
15706572.


121: Shin JH, Engidawork E, Delabar JM, Lubec G. Identification and
characterisation of soluble epoxide hydrolase in mouse brain by a robust protein
biochemical method. Amino Acids. 2005 Feb;28(1):63-9. Epub 2005 Feb 10. PubMed
PMID: 15700109.


122: Afjehi-Sadat L, Shin JH, Felizardo M, Lee K, Slavc I, Lubec G. Detection of
hypothetical proteins in 10 individual human tumor cell lines. Biochim Biophys
Acta. 2005 Feb 14;1747(1):67-80. Epub 2004 Nov 1. PubMed PMID: 15680240.


123: Czech T, Yang JW, Csaszar E, Kappler J, Baumgartner C, Lubec G. Reduction of
hippocampal collapsin response mediated protein-2 in patients with mesial
temporal lobe epilepsy. Neurochem Res. 2004 Dec;29(12):2189-96. PubMed PMID:
15672539.


124: Miguel RF, Pollak A, Lubec G. Metalloproteinase ADAMTS-1 but not ADAMTS-5 is
manifold overexpressed in neurodegenerative disorders as Down syndrome,
Alzheimer's and Pick's disease. Brain Res Mol Brain Res. 2005 Jan 5;133(1):1-5.
PubMed PMID: 15661359.


125: Kirchner L, Weitzdoerfer R, Hoeger H, Url A, Schmidt P, Engelmann M, Villar
SR, Fountoulakis M, Lubec G, Lubec B. Impaired cognitive performance in neuronal
nitric oxide synthase knockout mice is associated with hippocampal protein
derangements. Nitric Oxide. 2004 Dec;11(4):316-30. Epub 2004 Nov 25. PubMed PMID:
15604044.


126: Myung JK, Afjehi-Sadat L, Felizardo-Cabatic M, Slavc I, Lubec G.
Expressional patterns of chaperones in ten human tumor cell lines. Proteome Sci.
2004 Dec 14;2(1):8. PubMed PMID: 15598346; PubMed Central PMCID: PMC543454.


127: Yang JW, Czech T, Yamada J, Csaszar E, Baumgartner C, Slavc I, Lubec G.
Aberrant cytosolic acyl-CoA thioester hydrolase in hippocampus of patients with
mesial temporal lobe epilepsy. Amino Acids. 2004 Dec;27(3-4):269-75. Epub 2004
Dec 2. PubMed PMID: 15592755.


128: Lubec G. Editorial: is immunochemistry sufficient for protein detection,
characterisation and identification? Amino Acids. 2004 Dec;27(3-4):229. PubMed
PMID: 15592753.


129: Pollak D, Weitzdoerfer R, Yang YW, Prast H, Hoeger H, Lubec G. Cerebellar
protein expression in three different mouse strains and their relevance for motor
performance. Neurochem Int. 2005 Jan;46(1):19-29. PubMed PMID: 15567512.


130: Shin JH, Delabar JM, Lubec G. Mass spectrometrical analysis of
phosphoprotein enriched in astrocytes of 15 kDa in mouse hippocampi. Amino Acids.
2004 Dec;27(3-4):339-44. Epub 2004 Nov 5. PubMed PMID: 15538643.


131: Oh JE, Krapfenbauer K, Lubec G. Proteomic identification of collagens and
related proteins in human fibroblasts. Amino Acids. 2004 Dec;27(3-4):305-11. Epub
2004 Oct 4. PubMed PMID: 15455213.


132: Oh JE, Krapfenbauer K, Lubec G. Proteomic basis for the possible use of
lymphocytes for metabolic screenings. Amino Acids. 2004 Oct;27(2):141-7. Epub
2004 Oct 4. PubMed PMID: 15455212.


133: Afjehi-Sadat L, Gruber-Olipitz M, Felizardo M, Slavc I, Lubec G. Expression
of proteasomal proteins in ten different tumor cell lines. Amino Acids. 2004
Oct;27(2):129-40. Epub 2004 Oct 4. PubMed PMID: 15455211.


134: Kitzmueller E, Krapfenbauer K, Hoeger H, Weitzdoerfer R, Lubec G, Lubec B.
Life-long effects of perinatal asphyxia on stress-induced proteins and dynamin 1
in rat brain. Neurochem Res. 2004 Sep;29(9):1767-77. PubMed PMID: 15453273.


135: Prusa AR, Marton E, Rosner M, Bettelheim D, Lubec G, Pollack A, Bernaschek
G, Hengstschläger M. Neurogenic cells in human amniotic fluid. Am J Obstet
Gynecol. 2004 Jul;191(1):309-14. PubMed PMID: 15295384.


136: Shin JH, London J, Le Pecheur M, Höger H, Pollak D, Lubec G. Aberrant
neuronal and mitochondrial proteins in hippocampus of transgenic mice
overexpressing human Cu/Zn superoxide dismutase 1. Free Radic Biol Med. 2004 Sep
1;37(5):643-53. PubMed PMID: 15288122.


137: Pollak D, Krapfenbauer K, Fountoulakis M, Peyrl A, Lubec G. Expressional
pattern of known and predicted signaling proteins in seven human cell lines. J
Chromatogr B Analyt Technol Biomed Life Sci. 2004 Sep 5;808(2):185-208. PubMed
PMID: 15261812.


138: Weitzdoerfer R, Gerstl N, Pollak D, Hoeger H, Dreher W, Lubec G. Long-term
influence of perinatal asphyxia on the social behavior in aging rats.
Gerontology. 2004 Jul-Aug;50(4):200-5. PubMed PMID: 15258424.


139: Fountoulakis M, Tsangaris G, Oh JE, Maris A, Lubec G. Protein profile of the
HeLa cell line. J Chromatogr A. 2004 Jun 4;1038(1-2):247-65. PubMed PMID:
15233540.


140: Ferrando-Miguel R, Cheon MS, Lubec G. Protein levels of genes encoded on
chromosome 21 in fetal Down Syndrome brain (Part V): overexpression of
phosphatidyl-inositol-glycan class P protein (DSCR5). Amino Acids. 2004
Jun;26(3):255-61. Epub 2004 Mar 16. PubMed PMID: 15221505.


141: Afjehi-Sadat L, Krapfenbauer K, Slavc I, Fountoulakis M, Lubec G.
Hypothetical proteins with putative enzyme activity in human amnion, lymphocyte,
bronchial epithelial and kidney cell lines. Biochim Biophys Acta. 2004 Jul
1;1700(1):65-74. PubMed PMID: 15210126.


142: Salchner P, Lubec G, Engelmann M, Orlando GF, Wolf G, Sartori SB, Hoeger H,
Singewald N. Genetic functional inactivation of neuronal nitric oxide synthase
affects stress-related Fos expression in specific brain regions. Cell Mol Life
Sci. 2004 Jun;61(12):1498-506. PubMed PMID: 15197473.


143: Shin JH, Yang JW, Le Pecheur M, London J, Hoeger H, Lubec G. Altered
expression of hypothetical proteins in hippocampus of transgenic mice
overexpressing human Cu/Zn-superoxide dismutase 1. Proteome Sci. 2004 Jun
11;2(1):2. PubMed PMID: 15193154; PubMed Central PMCID: PMC446209.


144: Hengstschläger M, Rosner M, Fountoulakis M, Oh JE, Lubec G. Protein levels
of alpha1-tubulin, protein disulfide isomerase, tropomyosins and vimentin are
regulated by the tuberous sclerosis gene products. Cancer Lett. 2004 Jul
16;210(2):219-26. PubMed PMID: 15183538.


145: Shin JH, Gulesserian T, Weitzdoerfer R, Fountoulakis M, Lubec G. Derangement
of hypothetical proteins in fetal Down's syndrome brain. Neurochem Res. 2004
Jun;29(6):1307-16. PubMed PMID: 15176487.


146: Weitzdoerfer R, Hoeger H, Engidawork E, Engelmann M, Singewald N, Lubec G,
Lubec B. Neuronal nitric oxide synthase knock-out mice show impaired cognitive
performance. Nitric Oxide. 2004 May;10(3):130-40. PubMed PMID: 15158692.


147: Yang JW, Czech T, Lubec G. Proteomic profiling of human hippocampus.
Electrophoresis. 2004 Apr;25(7-8):1169-74. PubMed PMID: 15095461.


148: Salchner P, Lubec G, Singewald N. Decreased social interaction in aged rats
may not reflect changes in anxiety-related behaviour. Behav Brain Res. 2004 May
5;151(1-2):1-8. PubMed PMID: 15084415.


149: Shin JH, Weitzdoerfer R, Fountoulakis M, Lubec G. Expression of
cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog
(mitochondrial precursor) in fetal Down syndrome brain. Neurochem Int. 2004
Jul;45(1):73-9. PubMed PMID: 15082224.


150: Cheon MS, Kim SH, Fountoulakis M, Lubec G. Heart type fatty acid binding
protein (H-FABP) is decreased in brains of patients with Down syndrome and
Alzheimer's disease. J Neural Transm Suppl. 2003;(67):225-34. PubMed PMID:
15068254.


151: Lubec G, Sohn SY. RNA microarray analysis of channels and transporters in
normal and fetal Down syndrome (trisomy 21) brain. J Neural Transm Suppl.
2003;(67):215-24. PubMed PMID: 15068253.


152: Ferrando-Miguel R, Cheon MS, Yang JW, Lubec G. Overexpression of
transcription factor BACH1 in fetal Down syndrome brain. J Neural Transm Suppl.
2003;(67):193-205. PubMed PMID: 15068251.


153: Nicham R, Weitzdörfer R, Hauser E, Freidl M, Schubert M, Wurst E, Lubec G,
Seidl R. Spectrum of cognitive, behavioural and emotional problems in children
and young adults with Down syndrome. J Neural Transm Suppl. 2003;(67):173-91.
PubMed PMID: 15068250.


154: Unterberger U, Lubec G, Dierssen M, Stoltenburg-Didinger G, Farreras JC,
Budka H. The cerebral cortex in fetal Down syndrome. J Neural Transm Suppl.
2003;(67):159-63. PubMed PMID: 15068248.


155: Pollak D, Cairns N, Lubec G. Cytoskeleton derangement in brain of patients
with Down syndrome, Alzheimer's disease and Pick's disease. J Neural Transm
Suppl. 2003;(67):149-58. PubMed PMID: 15068247.


156: Shim KS, Bergelson JM, Furuse M, Ovod V, Krude T, Lubec G. Reduction of
chromatin assembly factor 1 p60 and C21orf2 protein, encoded on chromosome 21, in
Down syndrome brain. J Neural Transm Suppl. 2003;(67):117-28. PubMed PMID:
15068244.


157: Lubec G, Bajo M, Cheon MS, Bajova H, Matherly LH. Increased expression of
human reduced folate carrier in fetal Down syndrome brain. J Neural Transm Suppl.
2003;(67):95-103. PubMed PMID: 15068242.


158: Fountoulakis M, Gulesserian T, Lubec G. Overexpression of
C1-tetrahydrofolate synthase in fetal Down syndrome brain. J Neural Transm Suppl.
2003;(67):85-93. PubMed PMID: 15068241.


159: Sohn SY, Weitzdoerfer R, Mori N, Lubec G. Transcription factor REST
dependent proteins are comparable between Down syndrome and control brains:
challenging a hypothesis. J Neural Transm Suppl. 2003;(67):59-66. PubMed PMID:
15068239.


160: Shim KS, Ferrando-Miguel R, Lubec G. Aberrant protein expression of
transcription factors BACH1 and ERG, both encoded on chromosome 21, in brains of
patients with Down syndrome and Alzheimer's disease. J Neural Transm Suppl.
2003;(67):39-49. PubMed PMID: 15068237.


161: Oh JE, Fountoulakis M, Juranville JF, Rosner M, Hengstschläger M, Lubec G.
Proteomic determination of metabolic enzymes of the amnion cell: basis for a
possible diagnostic tool? Proteomics. 2004 Apr;4(4):1145-58. Erratum in:
Proteomics. 2004 Jun;4(6);1849. Hengstschlaeger, Markus [corrected to
Hengstschläger, Markus]. PubMed PMID: 15048995.


162: Shin JH, Yang JW, Juranville JF, Fountoulakis M, Lubec G. Evidence for
existence of thirty hypothetical proteins in rat brain. Proteome Sci. 2004 Jan
30;2(1):1. PubMed PMID: 14754459; PubMed Central PMCID: PMC373456.


163: Oh JE, Krapfenbauer K, Fountoulakis M, Frischer T, Lubec G. Evidence for the
existence of hypothetical proteins in human bronchial epithelial, fibroblast,
amnion, lymphocyte, mesothelial and kidney cell lines. Amino Acids. 2004
Feb;26(1):9-18. PubMed PMID: 14752611.


164: Lubec G. Brainprot - generating the proteome of the brain. Amino Acids. 2004
Feb;26(1):1-2. PubMed PMID: 14752609.


165: Hengstschläger M, Rosner M, Fountoulakis M, Lubec G. Tuberous sclerosis
genes regulate cellular 14-3-3 protein levels. Biochem Biophys Res Commun. 2003
Dec 19;312(3):676-83. PubMed PMID: 14680818.


166: Myung JK, Krapfenbauer K, Weitzdoerfer R, Peyrl A, Fountoulakis M, Lubec G.
Expressional pattern of chaperones in neuronal, glial, amnion, mesothelial, and
bronchial epithelial cell lines. Mol Genet Metab. 2003 Dec;80(4):444-50. PubMed
PMID: 14654358.


167: Peyrl A, Krapfenbauer K, Slavc I, Strobel T, Lubec G. Proteomic
characterization of the human cortical neuronal cell line HCN-2. J Chem
Neuroanat. 2003 Nov;26(3):171-8. PubMed PMID: 14615026.


168: Engidawork E, Gulesserian T, Fountoulakis M, Lubec G. Aberrant protein
expression in cerebral cortex of fetus with Down syndrome. Neuroscience.
2003;122(1):145-54. PubMed PMID: 14596856.


169: Myung JK, Gulesserian T, Fountoulakis M, Lubec G. Deranged hypothetical
proteins Rik protein, Nit protein 2 and mitochondrial inner membrane protein,
Mitofilin, in fetal Down syndrome brain. Cell Mol Biol (Noisy-le-grand). 2003
Jul;49(5):739-46. Erratum in: Cell Mol Biol (Noisy-le-grand). 2004 Mar;50(2):207.
Jae-Kyung, M [corrected to Myung, J K]. PubMed PMID: 14528910.


170: Gulesserian T, Engidawork E, Fountoulakis M, Lubec G. Decreased brain levels
of Lupus La protein and increased U5 small ribonucleoprotein-specific 40 kDa
protein in fetal Down syndrome. Cell Mol Biol (Noisy-le-grand). 2003
Jul;49(5):733-8. PubMed PMID: 14528909.


171: Peyrl A, Krapfenbauer K, Slavc I, Yang JW, Strobel T, Lubec G. Protein
profiles of medulloblastoma cell lines DAOY and D283: identification of
tumor-related proteins and principles. Proteomics. 2003 Sep;3(9):1781-800. PubMed
PMID: 12973738.


172: Hoeger H, Bubna-Littitz H, Engelmann M, Schwerdtner I, Schmid D, Lahoda R,
Seidl R, Lubec G, Lubec B. Perinatal asphyxia in the guinea pig leads to
morphologic but not neurologic, cognitive, or behavioral changes. J Investig Med.
2003 Jul;51(4):233-9. PubMed PMID: 12929740.


173: Hengstschläger M, Rosner M, Fountoulakis M, Lubec G. Regulation of PCNA and
CAF-1 expression by the two tuberous sclerosis gene products. Biochem Biophys Res
Commun. 2003 Aug 1;307(3):737-42. PubMed PMID: 12893285.


174: Cheon MS, Shim KS, Kim SH, Hara A, Lubec G. Protein levels of genes encoded
on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect
hypothesis (Part IV). Amino Acids. 2003 Jul;25(1):41-7. PubMed PMID: 12836057.


175: Krapfenbauer K, Fountoulakis M, Lubec G. A rat brain protein expression map
including cytosolic and enriched mitochondrial and microsomal fractions.
Electrophoresis. 2003 Jun;24(11):1847-70. PubMed PMID: 12783461.


176: Lubec G, Krapfenbauer K, Fountoulakis M. Proteomics in brain research:
potentials and limitations. Prog Neurobiol. 2003 Feb;69(3):193-211. Review.
PubMed PMID: 12758110.


177: Engidawork E, Gulesserian T, Fountoulakis M, Lubec G. Expression of
hypothetical proteins in human fetal brain: increased expression of hypothetical
protein 28.5kDa in Down syndrome, a clue for its tentative role. Mol Genet Metab.
2003 Apr;78(4):295-301. PubMed PMID: 12706381.


178: Krapfenbauer K, Engidawork E, Cairns N, Fountoulakis M, Lubec G. Aberrant
expression of peroxiredoxin subtypes in neurodegenerative disorders. Brain Res.
2003 Mar 28;967(1-2):152-60. PubMed PMID: 12650976.


179: Cheon MS, Kim SH, Ovod V, Kopitar Jerala N, Morgan JI, Hatefi Y, Ijuin T,
Takenawa T, Lubec G. Protein levels of genes encoded on chromosome 21 in fetal
Down syndrome brain: challenging the gene dosage effect hypothesis (Part III).
Amino Acids. 2003;24(1-2):127-34. PubMed PMID: 12624744.


180: Cheon MS, Bajo M, Kim SH, Claudio JO, Stewart AK, Patterson D, Kruger WD,
Kondoh H, Lubec G. Protein levels of genes encoded on chromosome 21 in fetal Down
syndrome brain: challenging the gene dosage effect hypothesis (Part II). Amino
Acids. 2003;24(1-2):119-25. PubMed PMID: 12624743.


181: Cheon MS, Kim SH, Yaspo ML, Blasi F, Aoki Y, Melen K, Lubec G. Protein
levels of genes encoded on chromosome 21 in fetal Down syndrome brain:
challenging the gene dosage effect hypothesis (Part I). Amino Acids.
2003;24(1-2):111-7. PubMed PMID: 12624742.


182: Engidawork E, Lubec G. Molecular changes in fetal Down syndrome brain. J
Neurochem. 2003 Mar;84(5):895-904. Review. PubMed PMID: 12603815.


183: Kastner P, Mosgoeller W, Fang-Kircher S, Kitzmueller E, Kirchner L, Hoeger
H, Seither P, Lubec G, Lubec B. Deficient brain RNA polymerase and altered
nucleolar structure persists until day 8 after perinatal asphyxia of the rat.
Pediatr Res. 2003 Jan;53(1):62-71. PubMed PMID: 12508083.


184: Greber-Platzer S, Fleischmann C, Nussbaumer C, Cairns N, Lubec G. Increased
RNA levels of the 25 kDa synaptosomal associated protein in brain samples of
adult patients with Down Syndrome. Neurosci Lett. 2003 Jan 16;336(2):77-80.
PubMed PMID: 12499044.


185: Bernert G, Fountoulakis M, Lubec G. Manifold decreased protein levels of
matrin 3, reduced motor protein HMP and hlark in fetal Down's syndrome brain.
Proteomics. 2002 Dec;2(12):1752-7. PubMed PMID: 12469345.


186: Kircher SG, Kim SH, Fountoulakis M, Lubec G. Reduced levels of DEAD-box
proteins DBP-RB and p72 in fetal Down syndrome brains. Neurochem Res. 2002
Oct;27(10):1141-6. PubMed PMID: 12462412.


187: Yoo BC, Krapfenbauer K, Cairns N, Belay G, Bajo M, Lubec G. Overexpressed
protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob
disease. Neurosci Lett. 2002 Dec 16;334(3):196-200. PubMed PMID: 12453628.


188: Fountoulakis M, Juranville JF, Dierssen M, Lubec G. Proteomic analysis of
the fetal brain. Proteomics. 2002 Nov;2(11):1547-76. PubMed PMID: 12442255.


189: Bajo M, Fruehauf J, Kim SH, Fountoulakis M, Lubec G. Proteomic evaluation of
intermediary metabolism enzyme proteins in fetal Down's syndrome cerebral cortex.
Proteomics. 2002 Nov;2(11):1539-46. PubMed PMID: 12442254.


190: Lubec G, Engidawork E. The brain in Down syndrome (TRISOMY 21). J Neurol.
2002 Oct;249(10):1347-56. Review. PubMed PMID: 12382149.


191: Greber-Platzer S, Balcz B, Fleischmann C, Lubec G. Using the quantitative
competitive RT-PCR technique to analyze minute amounts of different mRNAs in
small tissue samples. Methods Mol Biol. 2002;193:29-58. PubMed PMID: 12325518.


192: Krapfenbauer K, Yoo BC, Fountoulakis M, Mitrova E, Lubec G. Expression
patterns of antioxidant proteins in brains of patients with sporadic
Creutzfeldt-Jacob disease. Electrophoresis. 2002 Aug;23(15):2541-7. PubMed PMID:
12210213.


193: Kim SH, Fountoulakis M, Cairns NJ, Lubec G. Human brain nucleoside
diphosphate kinase activity is decreased in Alzheimer's disease and Down
syndrome. Biochem Biophys Res Commun. 2002 Aug 30;296(4):970-5. PubMed PMID:
12200143.


194: Kim SH, Shim KS, Lubec G. Human brain nascent polypeptide-associated complex
alpha subunit is decreased in patients with Alzheimer' s disease and Down
syndrome. J Investig Med. 2002 Jul;50(4):293-301. PubMed PMID: 12109594.


195: Weitzdoerfer R, Fountoulakis M, Lubec G. Reduction of actin-related protein
complex 2/3 in fetal Down syndrome brain. Biochem Biophys Res Commun. 2002 May
3;293(2):836-41. PubMed PMID: 12054546.


196: Lubec B, Labudova O, Hoeger H, Kirchner L, Lubec G. Expression of
transcription factors in the brain of rats with perinatal asphyxia. Biol Neonate.
2002;81(4):266-78. PubMed PMID: 12011571.


197: Shim KS, Lubec G. Drebrin, a dendritic spine protein, is manifold decreased
in brains of patients with Alzheimer's disease and Down syndrome. Neurosci Lett.
2002 May 24;324(3):209-12. PubMed PMID: 12009525.


198: Kim SH, Krapfenbauer K, Cheon MS, Fountoulakis M, Cairns NJ, Lubec G. Human
brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and
increased in Pick's disease. Neurosci Lett. 2002 Mar 22;321(3):169-72. PubMed
PMID: 11880199.


199: Engidawork E, Lubec G. Protein expression in Down syndrome brain. Amino
Acids. 2001 Dec;21(4):331-61. Review. PubMed PMID: 11858695.


200: Gulesserian T, Kim SH, Fountoulakis M, Lubec G. Aberrant expression of
centractin and capping proteins, integral constituents of the dynactin complex,
in fetal down syndrome brain. Biochem Biophys Res Commun. 2002 Feb
15;291(1):62-7. PubMed PMID: 11829462.


201: Peyrl A, Weitzdoerfer R, Gulesserian T, Fountoulakis M, Lubec G. Aberrant
expression of signaling-related proteins 14-3-3 gamma and RACK1 in fetal Down
syndrome brain (trisomy 21). Electrophoresis. 2002 Jan;23(1):152-7. PubMed PMID:
11824616.


202: Weitzdoerfer R, Fountoulakis M, Lubec G. Aberrant expression of
dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain. J
Neural Transm Suppl. 2001;(61):95-107. PubMed PMID: 11771764.


203: Gulesserian T, Engidawork E, Fountoulakis M, Lubec G. Antioxidant proteins
in fetal brain: superoxide dismutase-1 (SOD-1) protein is not overexpressed in
fetal Down syndrome. J Neural Transm Suppl. 2001;(61):71-84. PubMed PMID:
11771762.


204: Weitzdoerfer R, Dierssen M, Fountoulakis M, Lubec G. Fetal life in Down
syndrome starts with normal neuronal density but impaired dendritic spines and
synaptosomal structure. J Neural Transm Suppl. 2001;(61):59-70. PubMed PMID:
11771761.


205: Freidl M, Gulesserian T, Lubec G, Fountoulakis M, Lubec B. Deterioration of
the transcriptional, splicing and elongation machinery in brain of fetal Down
syndrome. J Neural Transm Suppl. 2001;(61):47-57. PubMed PMID: 11771760.


206: Engidawork E, Roberts JC, Hardmeier R, Scheper RJ, Lubec G. Expression of
the multidrug resistance P glycoprotein (Pgp) and multidrug resistance associated
protein (MRP1) in Down syndrome brains. J Neural Transm Suppl. 2001;(61):35-45.
PubMed PMID: 11771758.


207: Weitzdoerfer R, Stolzlechner D, Dierssen M, Ferreres J, Fountoulakis M,
Lubec G. Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation
inhibitor beta and histidine triad nucleotide-binding protein in fetal Down
syndrome brain. J Neural Transm Suppl. 2001;(61):347-59. PubMed PMID: 11771757.


208: Engidawork E, Baiic N, Fountoulakis M, Dierssen M, Greber-Platzer S, Lubec
G. Beta-amyloid precursor protein, ETS-2 and collagen alpha 1 (VI) chain
precursor, encoded on chromosome 21, are not overexpressed in fetal Down
syndrome: further evidence against gene dosage effect. J Neural Transm Suppl.
2001;(61):335-46. PubMed PMID: 11771756.


209: Yoo BC, Fountoulakis M, Dierssen M, Lubec G. Expression patterns of
chaperone proteins in cerebral cortex of the fetus with Down syndrome:
dysregulation of T-complex protein 1. J Neural Transm Suppl. 2001;(61):321-34.
PubMed PMID: 11771755.


210: Cheon MS, Fountoulakis M, Dierssen M, Ferreres JC, Lubec G. Expression
profiles of proteins in fetal brain with Down syndrome. J Neural Transm Suppl.
2001;(61):311-9. PubMed PMID: 11771754.


211: Lubec B, Yoo BC, Dierssen M, Balic N, Lubec G. Down syndrome patients start
early prenatal life with normal cholinergic, monoaminergic and serotoninergic
innervation. J Neural Transm Suppl. 2001;(61):303-10. PubMed PMID: 11771753.


212: Cheon MS, Fountoulakis M, Cairns NJ, Dierssen M, Herkner K, Lubec G.
Decreased protein levels of stathmin in adult brains with Down syndrome and
Alzheimer's disease. J Neural Transm Suppl. 2001;(61):281-8. PubMed PMID:
11771751.


213: Kim SH, Dierssen M, Ferreres JC, Fountoulakis M, Lubec G. Increased protein
levels of heterogeneous nuclear ribonucleoprotein A2/B1 in fetal Down syndrome
brains. J Neural Transm Suppl. 2001;(61):273-80. PubMed PMID: 11771750.


214: Kim SH, Nairn AC, Cairns N, Lubec G. Decreased levels of ARPP-19 and PKA in
brains of Down syndrome and Alzheimer's disease. J Neural Transm Suppl.
2001;(61):263-72. PubMed PMID: 11771749.


215: Seidl R, Cairns N, Lubec G. The brain in Down syndrome. J Neural Transm
Suppl. 2001;(61):247-61. Review. PubMed PMID: 11771748.


216: Bernert G, Sustrova M, Sovcikova E, Seidl R, Lubec G. Effects of a single
transdermal nicotine dose on cognitive performance in adults with Down syndrome.
J Neural Transm Suppl. 2001;(61):237-45. PubMed PMID: 11771747.


217: Kim SH, Fountoulakis M, Cairns N, Lubec G. Protein levels of human
peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down
syndrome. J Neural Transm Suppl. 2001;(61):223-35. PubMed PMID: 11771746.


218: Engidawork E, Gulesserian T, Balic N, Cairns N, Lubec G. Changes in
nicotinic acetylcholine receptor subunits expression in brain of patients with
Down syndrome and Alzheimer's disease. J Neural Transm Suppl. 2001;(61):211-22.
PubMed PMID: 11771745.


219: Kitzmueller E, Greber S, Fountoulakis M, Lubec G. Carbohydrate handling
enzymes in fetal Down syndrome brain. J Neural Transm Suppl. 2001;(61):203-10.
PubMed PMID: 11771744.


220: Balcz B, Kirchner L, Cairns N, Fountoulakis M, Lubec G. Increased brain
protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome
and Alzheimer's disease. J Neural Transm Suppl. 2001;(61):193-201. PubMed PMID:
11771743.


221: Engidawork E, Gulesserian T, Seidl R, Cairns N, Lubec G. Expression of
apoptosis related proteins: RAIDD, ZIP kinase, Bim/BOD, p21, Bax, Bcl-2 and
NF-kappaB in brains of patients with Down syndrome. J Neural Transm Suppl.
2001;(61):181-92. PubMed PMID: 11771742.


222: Gulesserian T, Engidawork E, Yoo BC, Cairns N, Lubec G. Alteration of
caspases and other apoptosis regulatory proteins in Down syndrome. J Neural
Transm Suppl. 2001;(61):163-79. PubMed PMID: 11771741.


223: Engidawork E, Balic N, Juranville JF, Fountoulakis M, Dierssen M, Lubec G.
Unaltered expression of Fas (CD95/APO-1), caspase-3, Bcl-2 and annexins in brains
of fetal Down syndrome: evidence against increased apoptosis. J Neural Transm
Suppl. 2001;(61):149-62. PubMed PMID: 11771740.


224: Engidawork E, Juranville JF, Fountoulakis M, Dierssen M, Lubec G. Selective
upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome
zeta chain and isopeptidase T in fetal Down syndrome. J Neural Transm Suppl.
2001;(61):117-30. PubMed PMID: 11771738.


225: Kim SH, Fountoulakis M, Dierssen M, Lubec G. Decreased protein levels of
complex I 30-kDa subunit in fetal Down syndrome brains. J Neural Transm Suppl.
2001;(61):109-16. PubMed PMID: 11771736.


226: Kim SH, Lubec G. Decreased alpha-endosulfine, an endogenous regulator of
ATP-sensitive potassium channels, in brains from adult Down syndrome patients. J
Neural Transm Suppl. 2001;(61):1-9. PubMed PMID: 11771735.


227: Bajo M, Yoo BC, Cairns N, Gratzer M, Lubec G. Neurofilament proteins NF-L,
NF-M and NF-H in brain of patients with Down syndrome and Alzheimer's disease.
Amino Acids. 2001;21(3):293-301. PubMed PMID: 11764410.


228: Engelmann M, Ludwig M, Singewald N, Ebner K, Sabatier N, Lubec G, Landgraf
R, Wotjak CT. Taurine selectively modulates the secretory activity of vasopressin
neurons in conscious rats. Eur J Neurosci. 2001 Oct;14(7):1047-55. PubMed PMID:
11683896.


229: Kim SH, Lubec G. Brain alpha-endosulfine is manifold decreased in brains
from patients with Alzheimer's disease: a tentative marker and drug target?
Neurosci Lett. 2001 Sep 14;310(2-3):77-80. PubMed PMID: 11585571.


230: Baran H, Kepplinger B, Herrera-Marschitz M, Stolze K, Lubec G, Nohl H.
Increased kynurenic acid in the brain after neonatal asphyxia. Life Sci. 2001 Aug
3;69(11):1249-56. PubMed PMID: 11521749.


231: Krapfenbauer K, Berger M, Lubec G, Fountoulakis M. Changes in the brain
protein levels following administration of kainic acid. Electrophoresis. 2001
Jun;22(10):2086-91. PubMed PMID: 11465509.


232: Engidawork E, Loidl F, Chen Y, Kohlhauser C, Stoeckler S, Dell'Anna E, Lubec
B, Lubec G, Goiny M, Gross J, Andersson K, Herrera-Marschitz M. Comparison
between hypothermia and glutamate antagonism treatments on the immediate outcome
of perinatal asphyxia. Exp Brain Res. 2001 Jun;138(3):375-83. PubMed PMID:
11460776.


233: Yoo BC, Lubec G. p25 protein in neurodegeneration. Nature. 2001 Jun
14;411(6839):763-4; discussion 764-5. PubMed PMID: 11459045.


234: Vlkolinský R, Cairns N, Fountoulakis M, Lubec G. Decreased brain levels of
2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's
disease. Neurobiol Aging. 2001 Jul-Aug;22(4):547-53. PubMed PMID: 11445254.


235: Krapfenbauer K, Berger M, Friedlein A, Lubec G, Fountoulakis M. Changes in
the levels of low-abundance brain proteins induced by kainic acid. Eur J Biochem.
2001 Jun;268(12):3532-7. PubMed PMID: 11422383.


236: Seidl R, Bidmon B, Bajo M, Yoo PC, Cairns N, LaCasse EC, Lubec G. Evidence
for apoptosis in the fetal Down syndrome brain. J Child Neurol. 2001
Jun;16(6):438-42. PubMed PMID: 11417611.


237: Kim SH, Vlkolinsky R, Cairns N, Fountoulakis M, Lubec G. The reduction of
NADH ubiquinone oxidoreductase 24- and 75-kDa subunits in brains of patients with
Down syndrome and Alzheimer's disease. Life Sci. 2001 May 4;68(24):2741-50.
PubMed PMID: 11400916.


238: Marx M, Mühl A, Hoeger H, Rolinski B, Frisch H, Herkner K, Lubec G, Lubec B.
Brain fatty acids in perinatal asphyxia. Life Sci. 2001 May 4;68(24):2657-64.
PubMed PMID: 11400909.


239: Yoo BC, Vlkolinsky R, Engidawork E, Cairns N, Fountoulakis M, Lubec G.
Differential expression of molecular chaperones in brain of patients with Down
syndrome. Electrophoresis. 2001 Apr;22(6):1233-41. PubMed PMID: 11358150.


240: Krapfenbauer K, Yoo BC, Kim SH, Cairns N, Lubec G. Differential display
reveals downregulation of the phospholipid transfer protein (PLTP) at the mRNA
level in brains of patients with Down syndrome. Life Sci. 2001 Mar
23;68(18):2169-79. PubMed PMID: 11324722.


241: Engidawork E, Gulesserian T, Seidl R, Cairns N, Lubec G. Expression of
apoptosis related proteins in brains of patients with Alzheimer's disease.
Neurosci Lett. 2001 May 4;303(2):79-82. PubMed PMID: 11311497.


242: Cheon MS, Bajo M, Gulesserian T, Cairns N, Lubec G. Evidence for the
relation of herpes simplex virus type 1 to Down syndrome and Alzheimer's disease.
Electrophoresis. 2001 Feb;22(3):445-8. PubMed PMID: 11258753.


243: Yoo BC, Cairns N, Fountoulakis M, Lubec G. Synaptosomal proteins,
beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP),
gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and
Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 May-Jun;12(3):219-25.
PubMed PMID: 11244216.


244: Seidl R, Cairns N, Singewald N, Kaehler ST, Lubec G. Differences between
GABA levels in Alzheimer's disease and Down syndrome with Alzheimer-like
neuropathology. Naunyn Schmiedebergs Arch Pharmacol. 2001 Feb;363(2):139-45.
PubMed PMID: 11218066.


245: Gulesserian T, Seidl R, Hardmeier R, Cairns N, Lubec G. Superoxide dismutase
SOD1, encoded on chromosome 21, but not SOD2 is overexpressed in brains of
patients with Down syndrome. J Investig Med. 2001 Jan;49(1):41-6. PubMed PMID:
11217146.


246: Seidl R, Labudova O, Krapfenbauer K, Henriksson EW, Craft J,
Turhani-Schatzmann D, Achsel T, Bidmon B, Pruijn GJ, Cairns N, Lubec G. Deficient
brain snRNP70K in patients with Down syndrome. Electrophoresis. 2001
Jan;22(1):43-8. PubMed PMID: 11197177.


247: Yoo BC, Fountoulakis M, Cairns N, Lubec G. Changes of voltage-dependent
anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with
Alzheimer's disease and Down syndrome. Electrophoresis. 2001 Jan;22(1):172-9.
PubMed PMID: 11197169.


248: Engidawork E, Gulesserian T, Yoo BC, Cairns N, Lubec G. Alteration of
caspases and apoptosis-related proteins in brains of patients with Alzheimer's
disease. Biochem Biophys Res Commun. 2001 Feb 16;281(1):84-93. PubMed PMID:
11178964.


249: Kim SH, Cairns N, Fountoulakisc M, Lubec G. Decreased brain
histamine-releasing factor protein in patients with Down syndrome and Alzheimer's
disease. Neurosci Lett. 2001 Mar 2;300(1):41-4. PubMed PMID: 11172935.


250: Yoo BC, Kim SH, Cairns N, Fountoulakis M, Lubec G. Deranged expression of
molecular chaperones in brains of patients with Alzheimer's disease. Biochem
Biophys Res Commun. 2001 Jan 12;280(1):249-58. PubMed PMID: 11162507.


251: Fountoulakis M, Hardmeier R, Höger H, Lubec G. Postmortem changes in the
level of brain proteins. Exp Neurol. 2001 Jan;167(1):86-94. PubMed PMID:
11161596.


252: Pollak A, Hayde M, Hayn M, Herkner K, Lombard KA, Lubec G, Weninger M,
Widness JA. Effect of intravenous iron supplementation on erythropoiesis in
erythropoietin-treated premature infants. Pediatrics. 2001 Jan;107(1):78-85.
PubMed PMID: 11134438.


253: Kim SH, Vlkolinsky R, Cairns N, Lubec G. Decreased levels of complex III
core protein 1 and complex V beta chain in brains from patients with Alzheimer's
disease and Down syndrome. Cell Mol Life Sci. 2000 Nov;57(12):1810-6. PubMed
PMID: 11130185.


254: Gulesserian T, Engidawork E, Cairns N, Lubec G. Increased protein levels of
serotonin transporter in frontal cortex of patients with Down syndrome. Neurosci
Lett. 2000 Dec 15;296(1):53-7. PubMed PMID: 11099832.


255: Seidl R, Tiefenthaler M, Hauser E, Lubec G. Effects of transdermal nicotine
on cognitive performance in Down's syndrome. Lancet. 2000 Oct
21;356(9239):1409-10. PubMed PMID: 11052587.


256: Kim SH, Yoo BC, Broers JL, Cairns N, Lubec G. Neuroendocrine-specific
protein C, a marker of neuronal differentiation, is reduced in brain of patients
with Down syndrome and Alzheimer's disease. Biochem Biophys Res Commun. 2000 Sep
16;276(1):329-34. PubMed PMID: 11006125.


257: Seidl R, Stöckler-Ipsiroglu S, Rolinski B, Kohlhauser C, Herkner KR, Lubec
B, Lubec G. Energy metabolism in graded perinatal asphyxia of the rat. Life Sci.
2000 Jun 16;67(4):421-35. PubMed PMID: 11003052.


258: Jörres RA, Holz O, Zachgo W, Timm P, Koschyk S, Müller B, Grimminger F,
Seeger W, Kelly FJ, Dunster C, Frischer T, Lubec G, Waschewski M, Niendorf A,
Magnussen H. The effect of repeated ozone exposures on inflammatory markers in
bronchoalveolar lavage fluid and mucosal biopsies. Am J Respir Crit Care Med.
2000 Jun;161(6):1855-61. PubMed PMID: 10852757.


259: Fountoulakis M, Hardmaier R, Schuller E, Lubec G. Differences in protein
level between neonatal and adult brain. Electrophoresis. 2000 Feb;21(3):673-8.
PubMed PMID: 10726776.


260: Hoeger H, Engelmann M, Bernert G, Seidl R, Bubna-Littitz H, Mosgoeller W,
Lubec B, Lubec G. Long term neurological and behavioral effects of graded
perinatal asphyxia in the rat. Life Sci. 2000;66(10):947-62. PubMed PMID:
10714895.


261: Moenkemann H, Labudova O, Yeghiazarian K, Rink H, Hoeger H, Lubec G.
Evidence that taurine modulates osmoregulation by modification of osmolarity
sensor protein ENVZ--expression. Amino Acids. 1999;17(4):347-55. PubMed PMID:
10707764.


262: Mosgoeller W, Kastner P, Fang-Kircher S, Kitzmueller E, Hoeger H, Seither P,
Labudova O, Lubec G, Lubec B. Brain RNA polymerase and nucleolar structure in
perinatal asphyxia of the rat. Exp Neurol. 2000 Jan;161(1):174-82. PubMed PMID:
10683283.


263: Schatzmann-Turhani D, Labudova O, Yeghiazaryan K, Rink H, Hauser E, Cairns
N, Lubec G. Overexpression of DNAse I in brain of patients with Down syndrome. J
Neural Transm Suppl. 1999;57:353-62. PubMed PMID: 10666689.


264: Fountoulakis M, Cairns N, Lubec G. Increased levels of 14-3-3 gamma and
epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome.
J Neural Transm Suppl. 1999;57:323-35. PubMed PMID: 10666687.


265: Yoo BC, Seidl R, Cairns N, Lubec G. Heat-shock protein 70 levels in brain of
patients with Down syndrome and Alzheimer's disease. J Neural Transm Suppl.
1999;57:315-22. PubMed PMID: 10666686.


266: Yeghiazaryan K, Turhani-Schatzmann D, Labudova O, Schuller E, Olson EN,
Cairns N, Lubec G. Downregulation of the transcription factor scleraxis in brain
of patients with Down syndrome. J Neural Transm Suppl. 1999;57:305-14. PubMed
PMID: 10666685.


267: Seidl R, Bajo M, Böhm K, LaCasse EC, MacKenzie AE, Cairns N, Lubec G.
Neuronal apoptosis inhibitory protein (NAIP)-like immunoreactivity in brains of
adult patients with Down syndrome. J Neural Transm Suppl. 1999;57:283-91. PubMed
PMID: 10666683.


268: Greber-Platzer S, Schatzmann-Turhani D, Cairns N, Balcz B, Lubec G.
Expression of the transcription factor ETS2 in brain of patients with Down
syndrome--evidence against the overexpression-gene dosage hypothesis. J Neural
Transm Suppl. 1999;57:269-81. PubMed PMID: 10666682.


269: Labudova O, Cairns N, Kitzmüller E, Lubec G. Impaired brain glucose
metabolism in patients with Down syndrome. J Neural Transm Suppl. 1999;57:247-56.
PubMed PMID: 10666680.


270: Seidl R, Kaehler ST, Prast H, Singewald N, Cairns N, Gratzer M, Lubec G.
Serotonin (5-HT) in brains of adult patients with Down syndrome. J Neural Transm
Suppl. 1999;57:221-32. PubMed PMID: 10666678.


271: Krapfenbauer K, Yoo BC, Cairns N, Lubec G. Differential display reveals
deteriorated mRNA levels of NADH3 (complex I) in cerebellum of patients with Down
syndrome. J Neural Transm Suppl. 1999;57:211-20. PubMed PMID: 10666677.


272: Lubec G, Nonaka M, Krapfenbauer K, Gratzer M, Cairns N, Fountoulakis M.
Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down syndrome
and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at
the protein level. J Neural Transm Suppl. 1999;57:161-77. PubMed PMID: 10666674.


273: Labudova O, Kitzmueller E, Rink H, Cairns N, Lubec G. Gene expression in
fetal Down syndrome brain as revealed by subtractive hybridization. J Neural
Transm Suppl. 1999;57:125-36. PubMed PMID: 10666672.


274: Kitzmueller E, Labudova O, Rink H, Cairns N, Lubec G. Altered gene
expression in fetal Down syndrome brain as revealed by the gene hunting technique
of subtractive hybridization. J Neural Transm Suppl. 1999;57:99-124. PubMed PMID:
10666671.


275: Greber-Platzer S, Balcz B, Cairns N, Lubec G. c-fos expression in brains of
patients with Down syndrome. J Neural Transm Suppl. 1999;57:75-85. PubMed PMID:
10666669.


276: Lubec G, Labudova O, Cairns N, Berndt P, Langen H, Fountoulakis M. Reduced
aldehyde dehydrogenase levels in the brain of patients with Down syndrome. J
Neural Transm Suppl. 1999;57:21-40. PubMed PMID: 10666666.


277: Gomez-Urquijo SM, Hökfelt T, Ubink R, Lubec G, Herrera-Marschitz M.
Neurocircuitries of the basal ganglia studied in organotypic cultures: focus on
tyrosine hydroxylase, nitric oxide synthase and neuropeptide immunocytochemistry.
Neuroscience. 1999;94(4):1133-51. PubMed PMID: 10625053.


278: Lubec B, Chiappe-Gutierrez M, Hoeger H, Kitzmueller E, Lubec G. Glucose
transporters, hexokinase, and phosphofructokinase in brain of rats with perinatal
asphyxia. Pediatr Res. 2000 Jan;47(1):84-8. PubMed PMID: 10625087.