1. Hasenhuetl PS, Schicker K, Koenig X, Li Y, Sarker S, Stockner T, Sucic S, Sitte HH, Freissmuth M, Sandtner W. Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction. Mol Pharmacol. 88(1), 12-8. 2015 doi: 10.1124/mol.115.099036.
  2. Koban F, El-Kasaby A, Häusler C, Stockner T, Simbrunner BM, Sitte HH, Freissmuth M, Sucic S. salt bridge linking the first intracellular loop with the C-terminus facilitates the folding of the serotonin transporter. J Biol Chem. 290(21), 13263-78. 2015. doi: 10.1074/jbc.M115.641357
  3. Zayats V, Stockner T, Pandey SK, Wörz K, Ettrich R, Ludwig J. A refined atomic scale model of the Saccharomyces cerevisiae K(+)-translocation protein Trk1p combined with experimental evidence confirms the role of selectivity filter glycines and other key residues. Biochim Biophys Acta. 2015 May;1848(5):1183-95, 2015, doi: 10.1016/j.bbamem.2015.02.007.
  4. Jurik A, Zdrazil B, Holy M, Stockner T, Sitte HH, Ecker GF. A binding mode hypothesis of tiagabine confirms liothyronine effect on γ-aminobutyric acid transporter 1 (GAT1). J Med Chem. 58(5), 2149-58, 2015 doi: 10.1021/jm5015428.
  5. Saha K, Partilla JS, Lehner KR, Seddik A, Stockner T, Holy M, Sandtner W, Ecker GF, Sitte HH, Baumann MH. ‘Second-Generation’ Mephedrone Analogs, 4-MEC and 4-MePPP, Differentially Affect Monoamine Transporter Function. Neuropsychopharmacology 40(6), 1321-31. 2015. doi: 10.1038/npp.2014.325.
  1. Fenollar-Ferrer C, Stockner T, Schwarz TC, Pal A, Gotovina J, Hofmaier T, Jayaraman K, Adhikary S, Kudlacek O, Mehdipour AR, Tavoulari S, Rudnick G, Singh SK, Konrat R, Sitte HH, Forrest LR. Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter. Biochemistry 53(33), 5444-60. 2014 doi: 10.1021/bi500637f.
  2. Rudashevskaya EL, Stockner T, Trauner M, Freissmuth M, Chiba P. Pharmacological correction of misfolding of ABC proteins. Drug Discov Today Technol. e87-94. 2014 doi: 10.1016/j.ddtec.2014.03.009.
  3. Singer J, Fazekas J, Wang W, Weichselbaumer M, Matz M, Mader A, Steinfellner W, Meitz S, Mechtcheriakova D, Sobanov Y, Willmann M, Stockner T, Spillner E, Kunert R, and Jensen-Jarolim E. Generation of a canine anti-EGFR (ErbB-1) antibody for passive immunotherapy in dog cancer patients. Mol Cancer Ther. 13(7), 1777-90. 2014 doi: 10.1158/1535-7163.MCT-13-0288.
  4. Burtscher V, Schicker K, Novikova E, Pöhn B, Stockner T, Kugler C, Singh A, Zeitz C, Lancelot ME, Audo I, Leroy BP, Freissmuth M, Herzig S, Matthes J, and Koschak A. Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2. Biochim Biophys Acta Biomembranes,1838(8), 2053-2065, 2014. doi: 10.1016/j.bbamem.2014.04.023.
  5. Dönmez Cakil Y, Khunweeraphong N, Parveen Z, Schmid D, Artaker M, Ecker GF, Sitte HH, Pusch O, Stockner T, and Chiba P. Pore-exposed tyrosine residues of p-glycoprotein are important hydrogen-bonding partners for drugs. Mol Pharmacol. 85(3), 420-8, 2014; doi: 10.1124/mol.113.088526.
  6. Chiba P, Freissmuth M, and Stockner T. Defining the blanks – Pharmacochaperoning of SLC6 transporters and ABC transporters. Pharmacol Res. 83, 63-73, 2014; doi: 10.1016/j.phrs.2013.11.009.
  7. Hofmaier T., Luf A, Seddik A, Stockner T, Holy M, Freissmuth M, Ecker GF, Schmid R, Sitte HH, and Kudlacek O. Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. Neurochem Int. [Published ahead of print] pii: S0197-0186(13)00307-0, 2013; doi: 10.1016/j.neuint.2013.11.010.
  8. Baumann MH, Bulling S, Benaderet TS, Saha K, Ayestas MA, Partilla JS, Ali SF, Stockner T, Rothman RB, Sandtner W, and Sitte HH. Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates. Neuropsychopharmacology, 39(6), 1355-65 2014; doi: 10.1038/npp.2013.331.
  1. Zayats V, Samad A, Minofar B, Roelofs KE, Stockner T, and Ettrich R. Regulation of the transient receptor potential channel TRPA1 by its N-terminal ankyrin repeat domain. Mol. Model. 19(11), 4689-700, 2013; DOI: 10.1007/s00894-012-1505-1.
  2. Lichtenegger M, Stockner T, Poteser M, Schleifer H, Platzer D, Romanin C, and Groschner K. A novel homology model of TRPC3 reveals allosteric coupling between gate and selectivity filter. Cell Calcium 54(3), 175-85, 2013; DOI: 10.1016/j.ceca.2013.05.010
  3. Buchmayer F, Schicker K, Geier P, Stübiger G, Hamilton PJ, Jurik A, Stockner T, Steinkellner T, Yang JW, Montgomery T, Holy M, Hofmaier T, Winkler MT, Kudlacek O, Matthies HJG, Ecker GF, Bochkov V, Galli A, Boehm S, and Sitte HH. Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate PNAS, 110(28), 11642-7, 2013; DOI: 10.1073/pnas.1220552110.
  4. Stockner T, Montgomery TR, Kudlacek O, Weissensteiner R, Ecker GF, Freissmuth M, and Sitte HH. Mutational Analysis of the High-Affinity Zinc Binding Site Validates a Refined Human Dopamine Transporter Homology Model. PLoS Comput. Biol. 9(2), e1002909, 2013; DOI: 10.1371/journal.pcbi.1002909.
  5. Sucic S, Koban F, El-Kasaby A, Kudlacek O, Stockner T, Sitte HH, and Freissmuth M. Switching the clientele: a lysine residing in the C-terminus of the serotonin transporter specifies its preference for the COPII component SEC24C. Biol. Chem. 288(8), 5330-41. 2013.
  6. Koehbach J, Stockner T, Bergmayr C, Muttenthaler M, and Gruber CW. Insights into the molecular evolution of oxytocin receptor ligand binding. Soc. Trans. 41(1), 197-204, 2013.
  7. Stockner T, and Koschak A. What can naturally occurring mutations tell us about Ca(v)1.x channel function? Biophys. Acta. 1828(7), 1598-607. 2013
  1. Bulling S, Schicker K, Zhang YW, Steinkellner T, Stockner T, Gruber C, Boehm S, Freissmuth M, Rudnick G, Sitte HH, and Sandtner W. The mechanistic basis for non-competitive ibogaine inhibition of serotonin and dopamine transporters. Biol. Chem. 287(22), 18524-34, 2012.
  2. Singer J, Weichselbaumer M, Stockner T, Mechtcheriakova D, Sobanov Y, Wrba F, Horvat R, Thalhammer JG, Willmann M, and Jensen-Jarolim E. Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting. Immunol. 50(4), 200-9, 2012.
  3. Schicker K, Uzelac Z, Gesmonde J, Bulling S, Stockner T, Freissmuth M, Boehm S, Rudnick G, Sitte HH, and Sandtner W. Unifying concept of serotonin transporter associated currents. J Biol Chem. 287, 438-45, 2012.
  1. Poteser M, Schleifer H, Lichtenegger M, Schernthaner M, Stockner T, Kappe O, Glasnov T, Romanin C. and Groschner K. PKC-dependent coupling of calcium permeation through transient receptor potential canonical 3 (TRPC3) to calcineurin signaling in HL-1 myocytes. PNAS 108(26), 10556-10561, 2011.
  2. Parveen Z, Stockner T, Bentele C, Pferschy S, Kraupp M, Freissmuth M, Ecker GF, and Chiba P. Molecular dissection of dual pseudosymmetric solute translocation pathways in human P-glycoprotein. Mol Pharmacol. 79(3), 443-52, 2011.
  1. Klepsch F, Stockner T, Erker T, Müller M, Chiba P, and Ecker GF. Using structural and mechanistic information to design novel inhibitors/substrates of P-glycoprotein. Top. Med. Chem. 10(17), 1769-74, 2010.
  2. Plochberger B, Stockner T, Chiantia S, Brameshuber M, Weguber J, Hermetter A, Schwille P, and Schütz GJ. Cholesterol slows down the lateral mobility of an oxidized phospholipid by pulling it into the bilayer. Lamuir, 26(22), 17322-29, 2010. Equally contributing first author
  3. Göbl C, Kosol S, Stockner T, Rückert HM, and Zangger K. Solution structure and membrane binding of the toxin fst of the par addiction module. Biochemistry, 49(31), 6567-75, 2010.
  4. Jerabek H, Georg Pabst G, Rappolt M, and Stockner T. Membrane mediated effect on ion channels induced by the anesthetic drug ketamine. Am. Chem. Soc. 132(23), 7990-7, 2010.
  5. Strawn R, Melichercik M, Green M, Stockner T, Carey J, and Ettrich R. Symmetric allosteric mechanism of hexameric Escherichia coli arginine repressor exploits competition between L-arginine ligands and resident arginine residues. PloS Comput Biol. 6, e1000801, 2010.
  6. Bak A, Polanski J, Stockner T, and Kurczyk A. MoStBioDat – Molecular and Structural Bioinformatics Database, Chem. & HTS, 13, 366-374, 2010.
  1. Stockner T, de Vries S, Bonvin AMJJ, Ecker GF, and Chiba P. Data-driven homology modelling of P-glycoprotein in the ATP-bound state indicates flexibility of the transmembrane domains. FEBS J. 276(4), 964-972, 2009.
  2. Chan DI, Stockner T, Tieleman DP, and Vogel HJ. Molecular dynamics simulations of the APO-, HOLO-, and ACYL- forms of Escherichia coli ACYL carrier protein. Bio. Chem. 283(48), 33620-3362, 2008.
  3. Ecker GF, Stockner T, and Chiba. P. Computational models for prediction of interactions with ABC-transporters. Drug Discovery Today 13, 311-317, 2008.
  4. Stockner T, Vogel HJ, and Tieleman DP. A salt-bridge motif involved in ligand binding and large scale domain motions of the maltose-binding protein. J. 89, 3362-3371, 2005.
  5. Stockner T, Ash WL, MacCallum JL, and Tieleman DP. Direct simulation of transmembrane helix association: role of asparagines. J. 87, 1650-1656, 2004.
  6. Ash WL, Stockner T, MacCallum JL, and Tieleman DP. Computer modeling of polyleucine-based coiled coil dimers in a realistic membrane environment: insight into helix-helix interactions in membrane proteins. Biochemistry 43, 9050-9060, 2004.
  7. Stockner T, Sterk H, Kaptein R, and Bonvin AMJJ. Molecular dynamics studies of a molecular switch in the glucocorticold receptor Mol. Biol. 328(2), 325-334, 2003.
  8. Paier J, Stockner T, Steinreiber A, Faber K, and Fabian WMF. Enantioselectivity of epoxide hydrolase catalysed oxirane ring opening: a 3D QSAR Study. Comp. Aided Mol. Des. 17(1) 1-11, 2003.
  9. Stockner T, Plugariu C, Koraimann G, Hogenauer G, Bermel W, Prytulla S. and Sterk H. Solution structure of the DNA-binding domain of TraM. Biochemistry 40(11), 3370-3377, 2001.
  10. Plugariu C, Stockner T, Moskau D, Koraimann G, Hogenauer G. and Sterk H. Conformational behaviour of the TraM headpiece. Pep. Res. 51(3), 244-250, 1998.
  11. Stockner T, Plugariu C. and Sterk H. Combined use of NMR and molecular modelling calculations for the conformational analysis of the TraM headpiece. Res. Chem. 36, S161-168, 1998.


  1. Stockner T, Juric A, Weissensteiner R, Freissmuth M, Ecker GF, and Sitte HH. Development of Refined Homology Models: Adding the Missing Information to the Medically Relevant Neurotransmitter Transporters; in Membrane Transport Mechanism, Springer Series in Biophysics 17, [In Press]; DOI 10.1007/978-3-642-53839-1_5,
  2. Strawn R, Stockner T, Melichercik M, Jin L, Xue W.F, Carey J, and Ettrich R. Synergy of molecular dynamics and isothermal titration calorimetry in studies of allostery. Methods Enzymol. 492, 151-88, 2011.