Barbara Bohle, PhD

Center for Physiology and Pathophysiology
Dept. of Pathophysiology/Division of Immunopathology
Währinger Gürtel 18-20
A-1090 Vienna, Austria
phone: + 431 40400 5114
fax:      + 431 40400 5130
Email:
barbara.bohle@meduniwien.ac.at
Website: http://www.meduniwien.ac.at/typo3/ipp/allergyresearch/

Research interests

Our laboratory is interested in elucidating the immunological mechanisms underlying the induction, maintenance and immunotherapy of Type I allergy and to develop novel concepts for an efficient and safe specific immunotherapy of Type I allergy.

Selected publications
 

Jahn-Schmid, B., N. Wopfner, G. Hubinger, R. Asero, C. Ebner, F. Ferreira and B. Bohle. The T cell response to Amb a 1 is characterized by three dominant epitopes and multiple MHC-restriction elements. J Allergy Clin Immunol. 2010 in press

Mutschlechner, S., M. Egger,  P. Briza, M. Wallner, P. Lackner, A. Karle,  A.B. Vogt, G.F. Fischer, B. Bohle* and F. Ferreira*. Naturally processed T cell-activating peptides of the major birch pollen allergen. J Allergy Clin Immunol. 125:711, 2010 
 

Schulten, V., A. Radakovics, C. Hartz, A. Mari, S. Vazquez-Cortes, M. Fernandez-Rivas, I. Lauer, B. Jahn-Schmid, T. Eiwegger, S. Scheurer and B. Bohle. Characterization of the allergic T cell response to Pru p 3, the non-specific lipid transfer protein in peach. J Allergy Clin Immunol., 124:100, 2009
 

Bohle, B., Kinaciyan, T., M. Gerstmayr, A. Radakovics, B. Jahn-Schmid, and C. Ebner. Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T cell tolerance and immune deviation. J Allergy Clin Immunol, 120:707, 2007