Rudolf Valenta, MD
Christian Doppler Laboratory for Allergy Research
Rudolf Valenta studied Medicine at the University of Vienna and obtained his MD degree in 1987 with distinction. He currently is full Professor for Allergology at the Medical University of Vienna and Foreign Adjunct Professor for Allergy at the Karolinska Institutet, Stockholm, Sweden. He co-ordinated two allergy research programs at the Medical University of Vienna, served as chairman of the standardization committee of the International Union of Immunological Societies (IUIS), as vice-president of the European Academy for Allergy and Clinical Immunology, as president of the Austrian Society for Allergology and Immunology and is member of the Austrian Academy of Sciences.
Basic and mechanistic studies of his group include the molecular characterization of cross-reactive allergens as explanation for allergic cross-reactivity, the demonstration of IgE autoreactivity as possible pathomechanism in severe allergy, and studies regarding the role of T cells and T cell-mediated pathology in allergy. In more recent work Rudolf Valenta has characterized rhinovirus coat proteins for serological diagnosis and for vaccination of rhinovirus infections which are major risk factors for severe asthma attacks.
Baranyi U, Farkas AM, Hock K, Mahr B, Linhart B, Gattringer M, Focke-Tejkl M, Petersen A, Wrba F, Rülicke T, Valenta R, Wekerle T. Cell Therapy for Prophylactic Tolerance in Immunoglobulin E-mediated Allergy. EbioMedicine 2016 May;7:230-9. doi: 10.1016/j.ebiom.2016.03.028. Epub 2016 Mar 2
Srinivasan B, Focke-Tejkl M, Weber M, Pahr S, Baar A, Atreya R, Neurath MF, Vogelsang H, Huber WD, Valenta R. Usefulness of recombinant γ-gliadin 1 for identifying patients with celiac disease and monitoring adherence to a gluten-free diet. J Allergy Clin Immunol. 2015 Dec;136(6):1607-18.e1-3. doi: 10.1016/j.jaci.2015.04.040. Epub 2015 Jun 13.
Wollmann E, Lupinek C, Kundi M, Selb R, Niederberger V, Valenta R. Reduction in allergen-specific IgE binding as measured by microarray: A possible surrogate marker for effects of specific immunotherapy. J Allergy Clin Immunol. 2015 Sep;136(3):806-809.e7. doi: 10.1016/j.jaci.2015.02.034
Gallerano D, Wollmann E, Lupinek C, Schlederer T, Ebner D, Harwanegg C, Niespodziana K, Schmetterer K, Pickl W, Puchhammer-Stöckl E, Sibanda E, Valenta R. HIV microarray for the mapping and characterization of HIV-specific antibody responses. Lab Chip. 2015 Mar 21;15(6):1574-89. doi: 10.1039/c4lc01510j.
Westman M, Lupinek C, Bousquet J, Andersson N, Pahr S, Baar A, Bergström A, Holmström M, Stjärne P, Lødrup Carlsen KC, Carlsen KH, Antó JM, Valenta R, van Hage M, Wickman M. Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescence.; Mechanisms for the Development of Allergies Consortium. J Allergy Clin Immunol. 2015 May;135(5):1199-206.e1-11. doi: 10.1016/j.jaci.2014.10.042. Epub 2014 Dec 18