Proteins are a kind of versatile micro-machines making life work. Human cells are capable of making more than 20.000 different proteins, considering posttranslational modifications we are talking about maybe a million different entities.
We try to understand what's going on in cells and tissues, by analysing the proteins expressed at a given functional (pathological) state. For that aim we investigate various kinds of in vitro reference systems and develop bioinformatics tools in order to define functional protein clusters. With the aid of these references we interpret clinical data. The presently pursued projects shall allow to
These aims can only be reached by close collaborations with the Division of Oncology, Departments of Medicine I, Dermatology and Surgery.
The present research activities are supported by
