Publications 2015

Schwarz C., Klaus D. A., Tudor B., Fleischmann E., Wekerle T., Roth G., Bodingbauer M., Kaczirek K. 2015. Transection Speed and Impact on Perioperative Inflammatory Response - A Randomized Controlled Trial Comparing Stapler Hepatectomy and CUSA Resection. PLoS One 10: e0140314

Schwarz C., Mayerhoffer S., Berlakovich G. A., Steininger R., Soliman T., Watschinger B., Bohmig G. A., Eskandary F., Konig F., Muhlbacher F., Wekerle T. 2015. Long-term outcome of belatacept therapy in de novo kidney transplant recipients - a case-match analysis. Transpl Int 28: 820-7

Pilat N., Klaus C., Hock K., Baranyi U., Unger L., Mahr B., Farkas A. M., Wrba F., Wekerle T. 2015. Polyclonal Recipient nTregs Are Superior to Donor or Third-Party Tregs in the Induction of Transplantation Tolerance. J Immunol Res 2015: 562935

Pilat N., Klaus C., Schwarz C., Hock K., Oberhuber R., Schwaiger E., Gattringer M., Ramsey H., Baranyi U., Zelger B., Brandacher G., Wrba F. , Wekerle T. 2015. Rapamycin and CTLA4Ig Synergize to Induce Stable Mixed Chimerism Without the Need for CD40 Blockade. Am J Transplant 15: 1568-79

Hock K., Mahr B., Schwarz C., Wekerle T. 2015. Deletional and regulatory mechanisms coalesce to drive transplantation tolerance through mixed chimerism. Eur J Immunol 45: 2470-9

Bohmig G. A., Farkas A. M., Eskandary F., Wekerle T. 2015. Strategies to overcome the ABO barrier in kidney transplantation. Nat Rev Nephrol

Publications 2014

P. E. Cippa, A. K. Kraus, J. Chen, Wekerle T., A. Guimezanes, R. P. Wuthrich, and T. Fehr, 'Bcl-2 Inhibition to Overcome Memory Cell Barriers in Transplantation', Am J Transplant, 14

Hock K, Pilat N, Baranyi U, Mahr B, Gattringer M, Klaus C, Wekerle T.  2014. Donor CD4 T cells trigger costimulation blockade-resistant donor bone marrow rejection through bystander activation requiring IL-6. Am J Transplant 14: 2011-22

Klintmalm GB, Feng S, Lake JR, Vargas HE, Wekerle T, Agnes S, Brown KA, Nashan B, Rostaing L, Meadows-Shropshire S, Agarwal M, Harler MB, García-Valdecasas JC. 2014. Belatacept-based Immunosuppression in De Novo Liver Transplant Recipients: One-Year Experience From a Phase II Randomized Study. Am J Transplant 14: 1817-1827

Pilat N, Farkas A, Mahr B, Schwarz C, Unger L, Hock K, Oberhuber R, Aumayr K, Wrba F, Wekerle T. 2014. T-regulatory cell treatment prevents chronic rejection of heart allografts in a murine mixed chimerism model. J Heart Lung Transplant 33: 429-437

Ahmadi S. M., Holzl M. A., Mayer E., Wekerle T., Heitger A. 2014. CTLA4-Ig preserves thymus-derived T regulatory cells. Transplantation 98: 1158-64

Schwarz C., Rasoul-Rockenschaub S., Soliman T., Berlakovich G., Steininger R., Muehlbacher F., Wekerle T. 2014. Belatacept treatment for 2 years after liver transplantation in not associated with operational tolerance. Clin Transplant 29: 85-9

Publications 2013

Cippa PE, Gabriel SS, Chen J, Bardwell PD, Bushell A, Guimezanes A, Kraus AK, Wekerle T, Wuthrich RP, Fehr T: Targeting apoptosis to induce stable mixed haematopoietic chimerism and long-term allograft survival without myelosuppressive conditioning in mice. Blood 2013 Aug 29, 122(9):1669-77.

Baranyi, U., M. Gattringer, A. Farkas, K. Hock, N. Pilat, J. Iacomini, R. Valenta, and T. Wekerle. 2013. The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism. Eur J Immunol 2013 Jun 14

Baranyi U, Valenta R, Wekerle T: Molecular chimerism in IgE-mediated allergy: B-and T-cell tolerance toward highly immunogenic exogenous antigens. Chimerism 2013, 4(1):29-31.

Gattringer M., Baranyi U., Pilat N., Hock K., Klaus C., Buchberger E., Ramsey H., Iacomini J., Valenta R., and Wekerle T. 2013. Engraftment of retrovirally transduced Bet v 1-GFP expressing bone marrow cells leads to allergen-specific tolerance. Immunobiology 2013, 218(9):1139-1146.

Hock, K., R. Oberhuber, Y. L. Lee, F. Wrba, T. Wekerle, and S. G. Tullius. 2013. Immunosenescence does not abrogate engraftment of murine allogeneic bone marrow. Transplantation 2013, 95(12):1431-1438.

Ramsey, H., N. Pilat, K. Hock, C. Klaus, L. Unger, C. Schwarz, U. Baranyi, M. Gattringer, E. Schwaiger, F. Wrba, and T. Wekerle. 2013. Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients. Transplant international : official journal of the European Society for Organ Transplantation 26: 206-218.

Publications 2011

Baranyi, U., Gattringer, M., Valenta, R., and Wekerle, T. Cell-based therapy in allergy. Curr Top Microbiol Immunol 352: 161-179 (2011)

Pilat, N., Sayegh,M. H. and Wekerle, T. Co-stimulatory pathways in transplantation. Sem Immunol 23: 293-303 (2011)

Baranyi, U., Gattringer,M., Boehm, A., Marth K., Focke-Tejkl M., Bohle B., Blatt, K., Valent, P., Valenta, R., and Wekerle T. Expression of a major plant allergen as membrane-anchored and secreted protein in human cells with preserved T cell and B cell epitopes. Int Arch Allergy Immunol 156: 259-266 (2011)

Kristo, I., Wilfingseder, J., Kainz, A.,Marschalek, J., Wekerle, T., Mühlbacher, F., Oberbauer,R. and Bodingbauer, M. Effect of intraportal infusion of tacrolimus on ischemic reperfusion injury in orthotopic liver transplantation: A randomised controlled trial. Transpl Int 24: 912-919 (2011)

Pilat, N., Klaus,C., Gattringer,M., Jaeckel,E.,Wrba, F., Golshayan, D., Baranyi,U. and WekerleT. Therapeutic efficacy of polyclonal Tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model. Transplantation 92: 280-288 (2011)