Dominik Filipp, PhD: "Enteric defensins, thymus and microbiota: essential players of intestinal autoimmunity"
Friday, May 22, 2015, 11.00 am, Vienna Competence Centre, Lazarettgasse 19, Vienna IX, seminar room, 1. floor
COLLOQUIUM IN PATHOPHYSIOLOGY, INFECTIOLOGY AND IMMUNOLOGY
Dominik Filipp, PhD: Head of the Laboratory of Immunobiology, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Selected papers:
- Filipp, D., Alizadeh-Khiavi, D., Richardson, C., Palma, A., Paredes, N., Takeuchi, O., Akira, S., Julius, M. H. 2001. Soluble CD14 enriched in colostrum and milk induces B cells growth and differentiation. Proc. Natl. Acad. Sci. USA 98:603-608.
- Filipp, D., Zhang, J., Leung, B. L., Shaw, A., Levin, S. D., Veillette, A. and Julius, M. 2003. Regulation of Fyn Trough Translocation of Activated Lck into Lipid Rafts. J. Exp. Medicine 197: 1221.
- Filipp, D., Moemeni, B., Ferzoco, A., Kathirkamathamby, K., Zhang, J., Ballek, O., Davidson, D., Veillette, A., and Julius, M. 2008. Lck dependent Fyn activation requires c-terminus dependent targeting of kinase active Lck to lipid rafts. J. Biol. Chemistry 283:26409- 26422.
- Balounová, J., Vavrochová, M T., Benešová, M., Ballek, O., Kolář, M. and Filipp, D. Toll-like receptors expressed on embryonic macrophages couple inflammatory signals to iron metabolism during early ontogenesis. 2014. Eur J Immunol, 44(5): 1491-502.
- Ballek, O., Valecka, J., Manning, J., Filipp, D. The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model. 2015. Immunol Cell Biol., 93: 384-395.
- Dobeš, J., Neuwirth, A., Dobešová, M., Vobořil, M., Balounová, J., Ballek, O., Lebl, J., Meloni, A., Krohn, K., Kluger, N., Ranki, A. and Filipp, D. Gastrointestinal autoimmunity associated with loss of central tolerance to enteric defensins. 2015. Gastroenterology. In press.
Host: Hannes Stockinger
zurück zu: CePII