Lab Location: Anna Spiegel Center of Translational Research, Level 5 and AKH, 8H
Associated Clinical Department: General Surgery
Tel + 43 1 40400 41690, 73525, 73526
We focus on the analysis of mechanisms of local metastasis in solid malignant tumors including tumor microenvironment and immunology. We use mainly omics technologies (transcriptomics, DNA-methylation, metabolomics, proteomics, etc.) and multicolor immunofluorescence staining of FFPE sections with computer-assisted analysis. In vitro models (cell culture, primary cells from tumors or ascites) will be used to validate results obtained by omics data or staining.
In addition, we try to develop methodologies to use network based technologies to integrate a multitude of data to understand and prognosticate complex biological and clinical characteristics, including therapy response and outcome (example picture showing a network integrating proteomics, free fatty acid analysis, eicosanoidomics, and laboratory parameters).
I am also interested in cooperations as bioinformatician on integrative omics-based and -supported studies of any translational research topic.