Our research focus is the treatment of different types of skin cancer with a special emphasis on malignat melanoma. The main topics investigated are immunotherapy, targeted therapy and vaccination with oncolytic viruses. The evaluation of efficacy, tolerability as well as different therapeutic combinations are performed on the basis of phase I to III clinical trials in the adjuvant and metastatic setting. The clinical research does also form the basis for translational research projects. Within these projects we are actively cooperating with international research institutions.