For the doctoral thesis Seminar # 902.218
Dr. Anna Repic, Prof. Dr. Johannes Huppa, Dr. Philipp
Schatzlmaier, Prof. Dr. Hannes Stockinger
Immunity to SARS-CoV-2: Exploring and
understanding the COVID-19 disease
Virtual meeting via Webex
Time: January 25-26, 2020
Meeting: Link
Meeting number (access code): 121 287 9576,
Meeting password: PredHH5zJ86 (77334459 from video systems)
Welcome, Introduction to and Overview of the Topic
Pathogenic and seasonal coronaviruses affecting
humans: similarities and differences
SARS-CoV-2 emergence and successful worldwide
spread: SARS-CoV-2 epidemiology and molecular
mechanisms that allowed successful global
transmission
Pathogenesis of COVID-19 I: Early infection (on the
cellular and tissue level), symptoms, pulmonary and
extrapulmonary manifestations
15.00 – 15.15 Break
Pathogenensis of COVID-19 II. Neurological and
olfactory manifestations (and underlying molecular
mechanisms), COVID-19 delirium and role of neuropilin-1
Effect of SARS-CoV-2 infection on systemic proteolytic
systems: renin–angiotensin–aldosterone system and
bradykinin, coagulation/fibrinolytic systems
Blood biomarkers as predictors of severe COVID-19
16.45 – 17.00 Discussion
Meeting: Link
Meeting number (access code): 121 925 8748,
Meeting password: xpC7nt3HV3s (97276834 from video systems)
SARS-CoV-2 mechanisms of host defence suppression
Role of T cells in recognizing and fighting SARS-CoV-2 infection
High age and underlying health conditions (obesity, hypertension, mutations in immune genes or
autoantibodies against type I IFNs) as risk factors for severe COVID-19
SARS-CoV-2 test, trace, isolate (and mask) strategy as
means to limit the virus spread
15.35 – 15.50 Break
COVID-19 treatments: differences in effectivity in vitro and in vivo
SARS-CoV-2 vaccine development: what it takes to make
a safe and effective vaccine and the current status of SARS-CoV-2 vaccines
(to a bonus topic: COVID-19 misinformation and how to
tackle it with scientific knowledge)