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WWTF promotes a project of Johannes Huppa with 800.000 EUR

Johannes Huppa receives a research grant of 800.000 euro from the Vienna Science and Technology Foundation (WWTF)more

 

Joint Danube Survey – the biggest river expedition worldwide: Microbiologists of the Unit for Water Hygiene investigate the microbial-faecal pollution patterns along the Danube

(Vienna, 3-09-2013) The international river expedition „Joint Danube Surey“, that is currently taking place at the Danube, lasting until the end of September, when the expedition ships reach the Danube delta. Microbiologists from...more

 

Regina Sommer zur FEMtech-Expertin des Monats gewählt

Regina Sommer, Leiterin der Abteilung Wasserhygiene am Institut für Angewandte Immunologie der MedUni Wien, ist FEMtech-Expertin des Monats August.more

 

Austrian Hygiene Award for Sonja Schauer (Water Hygiene)!

Within the frame of the 22nd Dosch Symposium of Hospital Hygiene, that took place in Velden/Wörthersee from June 3 to 5, 2013, the Austrian Hygiene Award was awarded for a publication of the department of Water Hygiene. more

 

Neptun-Water Award, Category WaterProtection, for the Project „Life Source Alpine Karstic Springs“

On March 20, 2013 the Neptun-Water Award (category WaterProtection), was confered to our cooperation partner Prof. Andreas Farnleitner on behalf of our Interuniversity Cooperation Centre Water & Health (www.waterandhealth.at) for...more

 

FWF supports a stand-alone project submitted by the Unit for Water Hygiene (Dr. Alexander Kirschner)

The Austrian Science Fund (FWF) has decided in its session from March 5/6, 2013, to support a further stand-alone project submitted by the Unit for Water Hygiene (Dr. Alexander Kirschner).more

 

Best Presentation Award for Karin Pfisterer

at the 10th EFIS-EJI Tatra Immunology Conference, held June 9-13, 2012, in Strbske Pleso, Slovakia more

 

Regina Sommer zur Präsidentin der ÖGHMP gewählt

Von 2012 bis 2014 Vorsitzende der Österreichischen Gesellschaft für Hygiene, Mikrobiologie und Präventivmedizin. more

 

Awards for Michael Riepl and Miranda Suchomel

During the 33rd Annual Meeting of the Austrian Society for Hygiene, Microbiology and Preventive Medicine the Prizes of hygiene, hospital- and industrial hygiene and microbiology for 2012 have been awared. more

 

FWF Decisions March 2012

During the last 2 days the Board of the FWF held one of its sophisticated meetings and did an enjoyable decision for our Institute:more

 

Internationaler Reinhard Liepolt Preis für Donauforschung

„Jackpot“ beim Internationalen Reinhard Liepolt Preis für Donauforschung für Mitarbeiter des Interuniversitären Kooperationszentrums Wasser & Gesundheit (ICC Water & Health)more

 

Excerpt of the radio program Ö1 "Radiokolleg"

Designing by Nora Kirchschlager and Ursula Mürling-Darrer more

 

Verleihung des Sonderpreises „WASSER“ der Stadt Wien

an Mitarbeiter des Interuniversity Cooperation Center Water & Healthmore

 

Safe Drinking Water in the 21st Century

A Presentation of the Interuniversity Cooperation Center Water & Health at Forum Alpbach more

 

Dimensions - the World of Science

The Ö1 radio programme "Dimensions - the World of Science" on the subject of "mini-proteins: small all-rounder?" which was designed by Mark Hammer and broadcasted on June 12, 2011 at 0705 pm, reported also...more

 

Peptide inhibits tumor growth

(Vienna, 14-02-2011) In a recent study Dr. Vladimir Leksa from the Molecular Immunology Unit of the Institute for Hygiene and Applied Immunology of the Center for Pathophysiology, Infectiology and Immunology describes a...more

 

Hannes Stockinger - Vorsitzender des VWGÖ

Univ.-Prof. Dr. Hannes Stockinger wurde kürzlich zum Vorsitzenden des Vereins der Wissenschaftlichen Gesellschaften Österreichs (VWGÖ) gewählt. more

 

Mitglieder unseres Instituts im neuen Vorstand der ÖGHMP

Kürzlich trat erstmalig der neu gewählte Vorstand der Österreichischen Gesellschaft für Hygiene, Mikrobiologie und Präventivmedizin (ÖGHMP) zusammen.more

 

Best Presentation by Roland Schürhagl at the Young Water Professionals Conference in Vienna

Roland Schürhagl (Unit for Water Hygiene) has been awarded the best presentation award for his contribution "Effect of membrane cleaning on microorganism retention by micro- and ultrafiltration in a membrane bioreactor for...more

 

The Austrian Science Fund accepts Vladimir Leksa´s project " Regulation of T cell activation by CD222"

At the last board meeting in June 2010, the Austrian Science Fund (FWF) accepted the project "The Integral Regulatory Role of the Mannose-6-Phosphate/Insulin-like Growth Factor 2 Receptor (CD222) in T cell activation" by Vladimir...more

 
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Inhaltsbereich

Advances in nanoscopy: Collaboration between MedUni Vienna and Vienna University of Technology provides insights into the nanostructure of cells

What were previously thought to be nanoprotein clusters on cell surfaces are often merely multiple counts. A method developed by Vienna University of Technology in collaboration with MedUni Vienna is now able to exclude artefacts and to examine cells nanoscopically.

Nanostructure of the key molecule Lck in human T-cells Using light, it is not possible to image structures smaller than half the wavelength – at least that was what we believed for a long time. However, the development of so-called nanoscopy has shown that this rule has certain loopholes. If different molecules are lit up at different times, they can ultimately be joined together to produce a sharp image. The Nobel prize for chemistry was awarded for this in 2014. Since then, nanoscopy has become a globally applied method, which is used to examine the structure of the cell membrane, amongst other things. However, these methods are very laborious and prone to errors and often lead to false conclusions. A new method that has recently been published in the leading journal "Nature Methods" by a team from Vienna University of Technology and MedUni Vienna, is able to filter out artefacts and recognize real nanostructures.

Nano cell imaging techniques for medical applications

"For many biological or medical problems, it is crucial to understand the exact structure of the cell membrane," says Florian Baumgart from the biophysics research group led by Gerhard Schütz at the Institute for Applied Physics at Vienna University of Technology. Nanoscopy is an ideal tool for examining the spatial arrangement of proteins on the cell membrane. This first opportunity to explore the nanoarchitecture of cells will provide new insights into the way cells function. "We are particularly interested in the nanoarchitecture of T-cells and antigen-presenting cells in the initiation of the adaptive immune response," says project partner Hannes Stockinger from the Institute for Hygiene and Applied Immunology at MedUni Vienna's Center for Pathophysiology, Infectiology and Immunology. The researchers are confident that they will be able to refine these novel methods, which allow cell resolution of less than 50 nm and even living cell analysis within microseconds, for the purposes of precision diagnostics. By mapping individual nanostructures and reactions, they hope to be able to create a new personalized biomarker profile, so that drug regimes can be specifically tailored to the individual in question.

Image: Nanostructure of the key molecule Lck in human T-cells

Link: http://dx.doi.org/10.1038/nmeth.3897

2016-06-14

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