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“The ubiquitin-proteasome system in genetic and obesity-linked immunometabolic disorders”

Colloquium in Pathophysiology, Infectiology and Immunologymore

 

Fantastische Bilanz des ICC Water & Health bei der 37. Jahrestagung der ÖGHMP

Nach CoVID-19 bedingter zweimaliger Absage und mit zweijähriger Verspätung konnte die 37. Jahrestagung der ÖGHMP (Österr. Gesellschaft für Hygiene, Mikrobiologie und Präventivmedizin) vom 31. Mai bis 2. Juni in Bad Ischl endlich...more

 

Oct. 11, 2021: Research for our drinking water

The Inter-University Cooperation Center for Water and Health (ICC Water & Health), in which Regina Sommer and Alexander Kirschner from our institute as well as the Vienna University of Technology and the Karl Landsteiner Private...more

 

Oct. 1, 2021: Trend magazine elected René Platzer, BSc MSc PhD as its next generation top researcher

To the press release more

 

Sept. 17, 2021: 'EFIS Best Poster Award'

Congratulations! Philipp Schatzlmaier, PostDoc at the Molecular Immunology Unit (HAI), won the 'EFIS Best Poster Award' at the 6th European Congress of Immunology, taking place September 1st to 4th. He was selected as one of...more

 

Sept. 14, 2021: Venugopal Gudipati was selected to give a talk in the Bright Sparks session at the European Congress of Immunology (ECI) 2021.

At the 6th European Congress of Immunology, held online from September 1 – 4, 2021, Venugopal Gudipati (HAI) from the Institute for Hygiene and Applied Immunology (HAI), was selected as one of the 24 Bright Sparks out of the...more

 

Sept. 3, 2021: Water hygiene department

is now the test center of the Austrian Association for Gas and Water ("ÖVGW")more

 

August 2, 2021: MedUni Wien "Researcher of the Month" August 2021, René Platzer, BSc MSc PhD

The “Researcher of the Month” jury gives the award for this month to René Platzer on the occasion of the work published in the top journal “Nature Communications” (IF 13.610) „Unscrambling fluorophore blinking for comprehensive...more

 

Poster price at the PhD Symposium 2021

Congratulation to Dr. Romana Klasinc and MSc. Carmen Rehm for their Poster price!more

 

MedUni Wien Researcher of the month, Mai 2021, Dr. Venugopal Gudipati

Inefficient CAR-proximal signaling blunts antigen detection.more

 

Honuring with the "Ehrennadel der Medizinischen Universität Wien"

On Friday , 2nd of October 2020 Prof. Dr. Hannes Stockinger and Univ. Prof. Dr. Gerhard Zalbinger were honoured by the Rector for their yearlong engagement and remarkable achievements for the Medical University with the...more

 

MedUni Wien "Researcher of the month", Juli 2020: Dr.in Sílvia Cervero-Aragó

Dr.in Sílvia Cervero-Aragó What are legionella bacteria, why can they become a problem and what can be done to prevent them from spreading? next...more

 

Empfehlungen zur Auswahl von Desinfektionsmitteln in Einrichtungen des Gesundheitswesens

Von Assoc. Prof. Dr. Miranda Suchomel, Institut für Hygiene und Angewandte Immunologiemore

 

Wie schütze ich mich am besten vor einer Ansteckung mit dem neuartigen Coronavirus SARS-CoV-2

Da noch keine Schutzimpfungen gegen SARS-CoV-2 existieren, stehen im Moment vor allem Hygienemaßnahmen zur Infektionsprävention im Vordergrund. more

 

Hannes Stockinger honored with Karl Landsteiner-Medal

At the annual meeting of the Austrian Society for Allergology and Immunology (ÖGAI) in Graz, Hannes Stockinger received the Karl Landsteiner-Medal for his merits for immunology, the highest immunological distinction awarded by...more

 

Markus Kraller wins Best Presentation Prize at Medical Postgraduate Conference

At the 16th International Medical Postgraduate Conference, held from 21 - 22 November 2019 in Hradec Králové, Czech Republic, Markus Kraller was awarded a Best Presentation Prizemore

 

Doctoral thesis completed: René Platzer

René Platzer, MSc, PhD – Molecular Immunology Unit – completed his doctoral thesis.more

 

Sílvia Cervero-Aragó wins Forum Water Hygiene Award

The Forum Water Hygiene awards the Science Prize 2018/19 for our latest work on the relevance of VBNC (viable but nonculturable) Legionella, which was recently published in the number 1 journal in the water sector "Water...more

 

Great success of the 20th symposium of the IWA Specialist Group Health-Related Water Microbiology in Vienna

The 20th symposium of the IWA Specialist Group Health-Related Water Microbiology, organized by ICC Water & Health and the Austrian Society for Hygiene, Microbiology and Preventive Medicine in Vienna (September 15–20, 2019, Campus...more

 

Great success for the 11th EFIS-EJI South Eastern European Immunology School (SEEIS2019)

At this year's summer school, held from 27 – 30 September 2019 in Pristina, Kosovo, 65 participants from 15 countries, especially from Eastern Europe, could benefit from lectures and workshops in basic and clinical immunology.more

 
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Article published by Hannes Stockinger recommended in F1000Prime as being of special significance in the field of Immunology by F1000 Faculty

F1000Prime is a continually updated collection of over 145,000 recommendations of top articles in biology and medicine, contributed by the F1000 Faculty.

The article – T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density., International Immunology, 1999 (DOI: 10.3410/f.1000986.793520162) –

has been recommended as being of special significance in the field of Immunology and rated "very good".

has

  • Read the recommendation of Faculty Member Neil Barclay, University of Oxford, Oxford, UK, F1000 Immunology:

„What affinity does an antibody need to be to give effective binding and/or cross-linking? This older paper is still highly relevant, as it describes the systematic analysis of binding of antibodies of varying affinities to T cells expressing CD147 and of activated T cells, which have increased levels of expression. The important findings are that low-affinity antibodies may not give detectable binding in typical labelling experiments unless there is sufficient antigen density, as found on activated T cells. This is a simpler interpretation rather than suggesting neoantigens appear due to activation, as have been proposed in other systems (e.g. CD2). In addition, the functional effects of high-affinity antibodies can be lower at higher concentrations where there may be a greater proportion of antibodies binding bivalently.“

 

  • Read the recommendation of Faculty Member Martin Hemler, Dana-Farber Cancer Institute, Boston, MA, USA, F1000 Cell Biology:

„The appearance of cell surface molecule "activation epitopes" is often assumed to involve protein conformational changes - this paper reminds us there may be a different, and simpler explanation for the appearance of new epitopes, in that low affinity protein clustering could easily be mistaken for protein "activation".

Using the cell surface CD147 protein as a model, it is demonstrated that protein clustering enables increased bivalent monoclonal antibody binding among relatively low affinity monoclonal antibodies.“

 

Heads of Faculty: Frederick Alt, Douglas Fearon and Philippa Marrack. 

 

Link: http://f1000.com/prime/1000986

01.07.2016

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