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“The ubiquitin-proteasome system in genetic and obesity-linked immunometabolic disorders”

Colloquium in Pathophysiology, Infectiology and Immunologymore

 

Fantastische Bilanz des ICC Water & Health bei der 37. Jahrestagung der ÖGHMP

Nach CoVID-19 bedingter zweimaliger Absage und mit zweijähriger Verspätung konnte die 37. Jahrestagung der ÖGHMP (Österr. Gesellschaft für Hygiene, Mikrobiologie und Präventivmedizin) vom 31. Mai bis 2. Juni in Bad Ischl endlich...more

 

Oct. 11, 2021: Research for our drinking water

The Inter-University Cooperation Center for Water and Health (ICC Water & Health), in which Regina Sommer and Alexander Kirschner from our institute as well as the Vienna University of Technology and the Karl Landsteiner Private...more

 

Oct. 1, 2021: Trend magazine elected René Platzer, BSc MSc PhD as its next generation top researcher

To the press release more

 

Sept. 17, 2021: 'EFIS Best Poster Award'

Congratulations! Philipp Schatzlmaier, PostDoc at the Molecular Immunology Unit (HAI), won the 'EFIS Best Poster Award' at the 6th European Congress of Immunology, taking place September 1st to 4th. He was selected as one of...more

 

Sept. 14, 2021: Venugopal Gudipati was selected to give a talk in the Bright Sparks session at the European Congress of Immunology (ECI) 2021.

At the 6th European Congress of Immunology, held online from September 1 – 4, 2021, Venugopal Gudipati (HAI) from the Institute for Hygiene and Applied Immunology (HAI), was selected as one of the 24 Bright Sparks out of the...more

 

Sept. 3, 2021: Water hygiene department

is now the test center of the Austrian Association for Gas and Water ("ÖVGW")more

 

August 2, 2021: MedUni Wien "Researcher of the Month" August 2021, René Platzer, BSc MSc PhD

The “Researcher of the Month” jury gives the award for this month to René Platzer on the occasion of the work published in the top journal “Nature Communications” (IF 13.610) „Unscrambling fluorophore blinking for comprehensive...more

 

Poster price at the PhD Symposium 2021

Congratulation to Dr. Romana Klasinc and MSc. Carmen Rehm for their Poster price!more

 

MedUni Wien Researcher of the month, Mai 2021, Dr. Venugopal Gudipati

Inefficient CAR-proximal signaling blunts antigen detection.more

 

Honuring with the "Ehrennadel der Medizinischen Universität Wien"

On Friday , 2nd of October 2020 Prof. Dr. Hannes Stockinger and Univ. Prof. Dr. Gerhard Zalbinger were honoured by the Rector for their yearlong engagement and remarkable achievements for the Medical University with the...more

 

MedUni Wien "Researcher of the month", Juli 2020: Dr.in Sílvia Cervero-Aragó

Dr.in Sílvia Cervero-Aragó What are legionella bacteria, why can they become a problem and what can be done to prevent them from spreading? next...more

 

Empfehlungen zur Auswahl von Desinfektionsmitteln in Einrichtungen des Gesundheitswesens

Von Assoc. Prof. Dr. Miranda Suchomel, Institut für Hygiene und Angewandte Immunologiemore

 

Wie schütze ich mich am besten vor einer Ansteckung mit dem neuartigen Coronavirus SARS-CoV-2

Da noch keine Schutzimpfungen gegen SARS-CoV-2 existieren, stehen im Moment vor allem Hygienemaßnahmen zur Infektionsprävention im Vordergrund. more

 

Hannes Stockinger honored with Karl Landsteiner-Medal

At the annual meeting of the Austrian Society for Allergology and Immunology (ÖGAI) in Graz, Hannes Stockinger received the Karl Landsteiner-Medal for his merits for immunology, the highest immunological distinction awarded by...more

 

Markus Kraller wins Best Presentation Prize at Medical Postgraduate Conference

At the 16th International Medical Postgraduate Conference, held from 21 - 22 November 2019 in Hradec Králové, Czech Republic, Markus Kraller was awarded a Best Presentation Prizemore

 

Doctoral thesis completed: René Platzer

René Platzer, MSc, PhD – Molecular Immunology Unit – completed his doctoral thesis.more

 

Sílvia Cervero-Aragó wins Forum Water Hygiene Award

The Forum Water Hygiene awards the Science Prize 2018/19 for our latest work on the relevance of VBNC (viable but nonculturable) Legionella, which was recently published in the number 1 journal in the water sector "Water...more

 

Great success of the 20th symposium of the IWA Specialist Group Health-Related Water Microbiology in Vienna

The 20th symposium of the IWA Specialist Group Health-Related Water Microbiology, organized by ICC Water & Health and the Austrian Society for Hygiene, Microbiology and Preventive Medicine in Vienna (September 15–20, 2019, Campus...more

 

Great success for the 11th EFIS-EJI South Eastern European Immunology School (SEEIS2019)

At this year's summer school, held from 27 – 30 September 2019 in Pristina, Kosovo, 65 participants from 15 countries, especially from Eastern Europe, could benefit from lectures and workshops in basic and clinical immunology.more

 
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Inhaltsbereich

Scientific double success for the ICC Water & Health: Austrian Microbiology Award and Hygiene Award 2018

At the 36th Annual Meeting of the Austrian Society for Hygiene, Microbiology and Preventive Medicine (ÖGHMP), held 4 – 7 June 2018 in Graz, both the Austrian Microbiology Award and the Austrian Hygiene Award 2018 were awarded to employees of ICC Water & Health.

A great success of the interuniversity cooperation of the Medical University Vienna, the TU Vienna and the Karl Landsteiner University in Krems.

The Austrian Microbiology Award 2018 went to the two employees of our institute Dr. Silvia Cervero-Aragó and Barbara Schrammel in the team of Prof. Alexander Kirschner from the Department of Water Hygiene (head: Prof. Regina Sommer) for their work* on viable but non-culturable (VBNC) legionellae. Significant scientific support also came from Dr. Anna Repic and Prof. Hannes Stockinger and Prof. Julia Walochnik, the head of the Research Group Molecular Parasitology at the Institute for Specific Prophylaxis and Tropical Medicine and her PhD student Elisabeth Dietersdorfer.

Legionella is the causative agent of Legionnaire's disease, one of the most common water-borne infectious diseases in industrial countries. Legionella is usually quantified in water samples using cultivation methods, but many recent studies have shown that the number of viable but nonculturable Legionella cells in water distribution systems can be many times higher than the number of culturable Legionella cells. The investigations tried to assess the potential health relevance of these VBNC legionellae by determining their viability with modern cytometric methods and their infectivity for human cell cultures in laboratory experiments. It was shown for the first time that 1) a considerable proportion of VBNC legionellae retain their viability over a long period of time and 2) these VBNC legionellae can directly infect human macrophages. However, this happens with significantly lower efficiency (longer infection time, higher infection dose, lower number of infected cells) than with culturable cells. Health relevance can therefore not be excluded; protracted disease progressions in immunocompromised persons could be explained by this.

This year's Austrian Hygiene Award was awarded to the two PhD students DI Claudia Kolm and Roland Martzy from the Molecular Diagnostics Group of the TU Vienna at the IFA Tulln under the direction of Dr. Georg Reischer (part of the TU Research Group Prof. Farnleitner) for their work** on the topic "Rapid methods for detecting faecal contamination". Both studies are concerned with the development and evaluation of isothermal amplification methods for the detection of enterococci in water and aim at the 23S rRNA gene as a marker for faecal contamination. To enable specific and simple detection, Claudia used a helicase-dependent amplification method, while in Rolands work LAMP (Loop-mediated isothermal amplification) was the method of choice. Regina Sommer contributed her expertise in the cultivation of enterococci strains to this successful cooperation. The microbiological methods currently used to detect faecal contaminations require a complex laboratory infrastructure and only provide results after one day. In contrast, the newly developed methods could be used on site and without a laboratory and provide information on contamination within one hour.

The work originated from the FWF single project "Health Relevance of VBNC Legionellae" and from the "IsoAmp" project funded by the Lower Austrian Education and Research Society. All publications are freely available on the Internet under the Open Access Option. The ICC Water & Health is a funded cooperation between the Technische Universität Wien, the Medical University of Vienna and - since 2017 - the Karl Landsteiner Private University for Health Sciences in Krems (www.waterandhealth.at).

The publications:

* Dietersdorfer E, Kirschner AKT, Schrammel B, Ohradanova-Repic A, Stockinger H, Sommer R, Walochnik J, Cervero-Aragó S (2018) Starved viable but non-culturable (VBNC) Legionella strains can infect and replicate in amoebae and human macrophages. Water Research 141 doi: 10.1016/j.watres.2018.01.058

* Schrammel B, Cervero-Arago S, Dietersdorfer E, Walochnik J, Lück C, Sommer R, Kirschner AKT (2018) Differential development of Legionella sub-populations during short- and long-term starvation. Water Research 141, doi: 0.1016/j.watres.2018.04.027

** Kolm, C., Martzy, R., Brunner, K., Mach, R.L. Krska, R., Heinze, G., Sommer, R., Reischer, G.H., Farnleitner, A.H., (2017) A complementary isothermal amplification method to the US EPA qPCR approach for the detection of enterococci in environmental waters. Environ Sci Technol 51(12): 7028-7035.

** Martzy, R., Kolm, C., Brunner, K., Mach, R.L. Krska, R., Šinkovec, H., Sommer, R., Farnleitner, A.H., Reischer, G.H. (2017) A loop-mediated isothermal amplification (LAMP) assay for the rapid detection of Enterococcus spp. in water. Water Res 122: 62-69.

 

 

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