Colorectal Neoplasms; Colorectal Surgery
After finishing my PhD focussing on transplant immunology and metabolic changes in end-stage liver disease/portal hypertension, my interest has evolved into the field of cancer- and immunometabolism.
My current research focus aims to better understand metabolic rewiring in stem cells during cancer development and to investigate the impact of secreted oncometabolites on tumor-infiltrating immune cells.
Techniques, methods & infrastructure
Basic research techniques/models:
- Standard molecular biology techniques
- CRISPR/Cas9 gene editing
- Murine in vivo models
- Intestinal organoids
- Confocal microscopy
- Establishment, maintenance and analysis of large clinical prospective and retrospective databases
- Establishment and maintenance of a colorectal cancer biobank