Dose-Response Relationship, Radiation; Heavy Ions; Medical Physics; Quality Assurance, Health Care; Radiation Oncology; Risk Management
Medical Radiation Research Head: Dietmar Georg Research Area: The vision of our group is the optimization of the treatment outcome of radiation oncology, alone or in combination with established chemotherapy or novel targeted strategies of drug treatment, with conventional photon or innovative ion-beams. Members:
Dose determination at the macroscopic and microscopic level
Image guided precision radiotherapy with high energy photon beams
MR guided radiation oncology
Supervised decision making and workflow automation
Proton, Carbon-ion and Helium-ion therapy
Dose response effects at cellular and tissue level (pre-clinical and clinical)
Techniques, methods & infrastructure
State-of-the-art photon beam linear accelerator with kV-based image guidance technology
State-of-the-art treatment planning for photon, proton, Carbon ion and brachytherapy
Comprehensive equipment for point dose, 2D and 3D dose measurements
GATE/GEANT4 based Monte Carlo simulations
Pre-clinical irradiator (kV beams) and pre-clinical imaging
Scanned proton and Carbon ions beam with active energy variation (synchrotron)
AI based on neural networks
Image guided particle therapy of uveal melanoma with a multiport beam arrangement (2019) Source of Funding: FFG (Austrian Research Promotion Agency), BRIDGE Principal Investigator
Proton and carbon ion response studies for chondrosarcoma – going beyond current radiobiological standards with 3D models (2019) Source of Funding: FWF (Austrian Science Fund), Stand alone project Coordinator of the collaborative project
Magnetic resonance imaging guided proton therapy (2018) Source of Funding: FWF (Austrian Science Fund), Programme Clinical Research (KLIF) Principal Investigator
Verhaegen, F. et al., 2018. ESTRO ACROP: Technology for precision small animal radiotherapy research: Optimal use and challenges. Radiotherapy and Oncology, 126(3), pp.471–478. Available at: http://dx.doi.org/10.1016/j.radonc.2017.11.016.
Daniel, M. et al., 2017. Impact of hybrid PET/MR technology on multiparametric imaging and treatment response assessment of cervix cancer. Radiotherapy and Oncology, 125(3), pp.420–425. Available at: http://dx.doi.org/10.1016/j.radonc.2017.10.036.
Fuchs, H. et al., 2017. Magnetic field effects on particle beams and their implications for dose calculation in MR-guided particle therapy. Medical Physics, 44(3), pp.1149–1156. Available at: http://dx.doi.org/10.1002/mp.12105.
Georg, D., Knöös, T. & McClean, B., 2011. Current status and future perspective of flattening filter free photon beams. Medical Physics, 38(3), pp.1280–1293. Available at: http://dx.doi.org/10.1118/1.3554643.
Georg, D. et al., 2008. Image-Guided Radiotherapy for Cervix Cancer: High-Tech External Beam Therapy Versus High-Tech Brachytherapy. International Journal of Radiation Oncology*Biology*Physics, 71(4), pp.1272–1278. Available at: http://dx.doi.org/10.1016/j.ijrobp.2008.03.032.