Head: Enikö Kállay, Ph.D. Assoc. Prof.
The goal of the Tumour Pathology Research Group is to understand and unveil cellular and molecular mechanisms that play a role in the prevention and pathogenesis of colorectal cancer and other chronic or malignant diseases. We are studying the role of vitamin D and dietary calcium in this process as well.
A further main task is to educate and train pre- and postgraduate students to become excellent scientists in biological and experimental medical research.
Our current major research interests are
1. Examination of calcium-dependent anti-tumour molecular mechanisms,
2. Role of the calcium sensing receptor (CaSR) in colorectal carcinogenesis;
3. Identification of genetic and epigenetic mechanisms that regulate the action of calcium and vitamin D in tumourigenesis;
4. Investigation of the vitamin D system as physiological defence against tumour progression;
5. Impact of the vitamin D catabolizing enzyme 25-hydroxyvitamin D 24 Hydroxylase on colon tumourigenesis.
6. Site- and gender-specific development of colorectal tumours