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AID/APOBECs among important factors in body’s defence against SARS-CoV-2

Research team comprising Anastasia Meshcheryakova, Diana Mechtcheriakova and Peter Pietschmann from the Institute of Pathophysiology and Allergy Research has addressed the potential interrelations between AID/APOBECs and the...[more]

 

"Imaging Modalities for Biological and Preclinical Research: A Compendium", with unique, comprehensive collection of about 100 state-of-the-art imaging technologies.

Anastasia Meshcheryakova, Felicitas Mungenast and Diana Mechtcheriakova (Research Group Molecular Systems Biology and Pathophysiology, Department of Pathophysiology and Allergy Research, Medical University of Vienna) – experts in...[more]

 

IgE-cross-blocking antibodies to Fagales following sublingual immunotherapy with recombinant Bet v 1

João Rodrigues Grilo, Claudia Kitzmüller, Lorenz Aglas, Gabriela Sánchez Acosta, Ute Vollmann, Christof Ebner, Fritz Horak, Tamar Kinaciyan, Christian Radauer, Fatima Ferreira, Beatrice Jahn-Schmid, and Barbara Bohle Allergy....[more]

 

Amino Acid Transporter LAT1 (SLC7A5) Mediates MeHg-Induced Oxidative Stress Defense in the Human Placental Cell Line HTR-8/SVneo.

Granitzer S, Widhalm R, Forsthuber M, Ellinger I, Desoye G, Hengstschläger M, Zeisler H, Salzer H, Gundacker C. Amino Acid Transporter LAT1 (SLC7A5) Mediates MeHg-Induced Oxidative Stress Defense in the Human Placental Cell...[more]

 

The Immune Phenotype of Isolated Lymphoid Structures in Non-Tumorous Colon Mucosa Encrypts the Information on Pathobiology of Metastatic Colorectal Cancer

The gut-associated lymphoid tissue represents an integral part of the immune system. Among the powerful players of the mucosa-associated lymphoid tissue are isolated lymphoid structures, ILSs. Additionally, in the course of...[more]

 

In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta

Sebastian Granitzer, Isabella Ellinger, Rumsha Khan, Katharina Gelles, Raimund Widhalm, Markus Hengstschläger, Harald Zeisler, Gernot Desoye, Lenka Tupova, Martina Ceckova, Hans Salzer, Claudia Gundacker Archives of Toxicology,...[more]

 

NSG mice humanized with allergen-specific T cell lines as in vivo model of respiratory allergy

Vizzardelli, C., F. Zimmann, B. Nagl, C. Kitzmüller, U. Vollmann, M. Gindl, S. Tangermann, B. Jahn-Schmid, L. Kenner, and B. Bohle. NSG mice humanized with allergen-specific T cell lines as in vivo model of respiratory allergy....[more]

 
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Inhaltsbereich

Amirreza Mahbod, Post-Doc in the group of Isabella Ellinger, has achieved PLACE 1 in the leaderboard of the MICCAI 2021 Foot Ulcer Segmentation Challenge.

Foot ulcer is a common complication of diabetes mellitus; it is associated with substantial morbidity and mortality and remains a major risk factor for lower leg amputation. Extracting accurate morphological features from the foot wounds is crucial for proper treatment. Computer-mediated approaches enable segmentation of the lesions and extraction  of related morphological features. Deep learning-based methods and more specifically convolutional neural networks (CNN) have shown excellent performances for various image segmentation tasks including medical image segmentation. In this work, Amirreza Mahbod, Rupert Ecker and Isabella Ellinger proposed an ensemble approach based on two encoder-decoder-based CNN models, namely LinkNet and UNet, to perform foot ulcer segmentation. Our method achieved the first rank in the FUSeg challenge leaderboard.

Leaderboard link: https://uwm-bigdata.github.io/wound-segmentation/

Challenge link: https://fusc.grand-challenge.org/

Method description: https://arxiv.org/abs/2109.01408

 
 
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