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Nitrated food proteins induce a regulatory immune response associated with allergy prevention after oral exposure in a Balb/c mouse food allergy model

Samadi N, Klems M, Heiden D, Bauer R, Kitzmüller C, Weidmann E, Ret D, Ondracek AS, Duschl A, Horejs-Hoeck J, Untersmayr E. Allergy. 2019 Aug 24. doi: 10.1111/all.14030. PMID: 31444907[more]

 

Activated T cells enhance the antigen-presenting capacity of human neutrophils!

Samadi N, Polak D, Kitzmüller C, Steinberger P, Zlabinger GJ, Jahn-Schmid B, Bohle B. Eur J Immunol. 2019. doi: 10.1002/eji.201848057. PMID: 31332790 [more]

 

Country-wide medical records infer increased allergy risk of gastric acid inhibition

July 30, 2019, Nature Communications 10, 3298, by Jordakieva et al.: Antiacids drugs prime subsequent anti-allergy prescriptions. 30% of 30-years old, and 33% of 60-year old Austrians are treated with gastric acid-inhibitors....[more]

 

Sublinguale Immuntherapie mit Apfelallergen mildert die allergen-spezifische Th2 Antwort

Sublingual immunotherapy with recombinant Mal d 1 downregulates the allergen-specific Th2 response. Kitzmüller C, Jahn-Schmid B, Kinaciyan T, Bohle B. Allergy. 2019 Aug;74(8):1579-1581. doi: 10.1111/all.13779. Epub 2019 Apr...[more]

 

Taking systems biology to ovarian cancer

A study published in Computational and Structural Biotechnology Journal and conducted by Anastasia Meshcheryakova from the Systems Biology and Pathophysiology Group of Diana Mechtcheriakova together with colleagues from the...[more]

 

Neutrophile Granulozyten - „bad guys“ in der allergischen Spätreaktion

Erst kürzlich konnte Dominika Polak aus der Arbeitsgruppe „Allergieforschung“ unter der Leitung von Barbara Bohle zeigen, dass Neutrophile Granulozyten in der Spätphase (Entzündungsphase) der IgE-mediierten Allergie Eigenschaften...[more]

 

New stories from old bones

Citation: Nebot E, Heimel P, Tangl S, Dockner M, Patsch J, Weber GW, Pretterklieber M, Teschler-Nicola M, Pietschmann P. Paget’s disease of long bones: microstructural analyses of historical bone samples. Calcif Tissue Int 2019....[more]

 
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Inhaltsbereich

Amirreza Mahbod, Post-Doc in the group of Isabella Ellinger, has achieved PLACE 1 in the leaderboard of the MICCAI 2021 Foot Ulcer Segmentation Challenge.

Foot ulcer is a common complication of diabetes mellitus; it is associated with substantial morbidity and mortality and remains a major risk factor for lower leg amputation. Extracting accurate morphological features from the foot wounds is crucial for proper treatment. Computer-mediated approaches enable segmentation of the lesions and extraction  of related morphological features. Deep learning-based methods and more specifically convolutional neural networks (CNN) have shown excellent performances for various image segmentation tasks including medical image segmentation. In this work, Amirreza Mahbod, Rupert Ecker and Isabella Ellinger proposed an ensemble approach based on two encoder-decoder-based CNN models, namely LinkNet and UNet, to perform foot ulcer segmentation. Our method achieved the first rank in the FUSeg challenge leaderboard.

Leaderboard link: https://uwm-bigdata.github.io/wound-segmentation/

Challenge link: https://fusc.grand-challenge.org/

Method description: https://arxiv.org/abs/2109.01408

 
 
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