Senior Supervisor N094 & N790
Malignant pleural mesothelioma, activin signaling, FGF/FGF-receptor signaling, biomarkers, therapeutic targets, mesothelioma-associated fibroblasts, epithelial to mesenchymal transition, Y-box binding protein 1.
Our research is focused on growth factors and their receptors in cancer development, therapy and drug resistance.
We aim to
(a) understand how growth factor signals contribute to malignancy
(b) translate this knowledge into strategies for therapeutic interventions and
(c) characterize mechanisms that determine sensitivity versus resistance of tumors to therapeutics interfering with growth factor signaling.