Medical University of Vienna
Department of Pathobiochemistry and Genetics
Institute of Medical Genetics
Währinger Straße 10
1090 Vienna, Austria
Phone: +43 1 40160 56540
E-Mail: mario.mikula@meduniwien.ac.at
Junior Supervisor N094
Skin organoid generation, hPSC differentiation, model systems for melanoma metastasis, tumor specific signaling, cholesterol homeostasis, role of tumor associated macrophages.
My research focuses on mechanisms of metastatic melanoma spread.
Specifically my group works on: establishment of a human skin organoid model, genomic changes and biomarkers, which accompany melanoma progression; impact of differentiation on melanoma development and the role of lipid homeostasis during the metastatic process.
It is my main research goal to increase our understanding of developmental programs linked to and thereby controlling melanoma metastasis.