Function:

Junior Supervisor N094 & N790

Research Interests:

BRCA1/2 genes, hereditary breast and ovarian cancer, early detection of cancer, cancer epidemiology, risk prediction models, quality of life, supportive care needs, survival

Research Focus:

My research interests cover all aspects of the epidemiology of hereditary breast and ovarian cancer, ranging from etiology and prevention to diagnosis, quality of life, supportive care needs and survival.

A particular focus is on developing risk prediction models and improving health services and outcomes for the high-risk cancer population.

Much of this work is conducted within the Austrian Hereditary Cancer National Study (ATHENA), International BRCA1/2 Carrier Cohort Study (IBCCS), Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), and Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA).

Funding has recently been obtained for two new projects:

1. PREDICTOME Study (WWTF, 2021-2024) that will develop a validated machine-learning model for predicting pathologic complete response in breast cancer patients towards safely omitting surgery based on early neoadjuvant chemotherapy response, and
2. identification and molecular analyses of brain metastasis in breast cancer patients study (CCC, 2022-2024) that aims to identify new gene targets that facilitate metastasis and to assess if breast cancer patients with BRCA1 mutation have a higher risk of brain metastasis.