Claudius Doerr

Research Group
Lung

Department
Department of Anesthesia, General Intensive Care and Pain Management,
Medical University of Vienna, Austria

Current academic degree
MD

Previous University
Medical University of Vienna

Project title

Positive effects of non-invasive ventilation on cerebral oxygenation 

Project description
Background: The proper management of brain oxygenation is an essential component of all anaesthesiologic procedures. Nevertheless, the brain remains one of the least monitored organs in the perioperative phase and intensive care therapy.

The INVOS Brain Oxymeter (IBO) is a reliable trend monitor for changes in regional cerebral oxygenation (rSO2).

It is a current assumption that rSO2 directly correlates with Sa02, which can be influenced by different ventilation assistance systems, e.g. CPAP therapy.

Objectives: The project aims at investigating changes of rSO2 in patients undergoing CPAP therapy for max. 15 minutes, in order to evaluate the effect of CPAP on cerebral oxygenation.

Methods: NIRS measurement (with IBO) will be performed on the temporoparietal cortex on both sides of the head. The trial will consist of two parts i.e. with or without ventilatory assistance. The order of starting the study with or without CPAP therapy will be randomized. During each part the measurements will be performed for 15min. After each interval a BGA (blood gas analysis) will be performed.