Medical University of Vienna, Division of Cardiology
Current academic degree
Dr. med. univ.
Technical University Munich, Germany
Risk stratification and management of patients with aortic valve disease
Aortic valve disease is frequently encountered in clinical practice with a prevalence of 2% in patients between 65 and 75 years and of 6% in patients older than 75 years in population-based studies. Many controversies exist regarding the proper management of patients with aortic valve disease. High-risk populations of patients need to be defined in order to risk stratify and select patients that might benefit from early elective surgery. Medical management of patients that have not yet developed criteria for surgery is not always performed in an appropriate setting resulting in delayed referral for surgery. Although the potential role of heart valve clinics (HVC) for the management of patients with valvular heart disease is recognized, their potential clinical benefits have not been assessed.
Frequently, significant aortic stenosis and regurgitation are found in the same patient, however a strict lack of data on the natural history and epidemiological prevalence of mixed aortic valve disease exists. Furthermore, aortic stenosis is found predominantly in elderly patients. Most studies that have investigated the natural history of aortic stenosis have included patients younger than 70 years.
The aims of the present thesis thus were:
- To describe the natural history of combined stenotic and regurgitant aortic valve disease
- To describe tha natural history of severe asymptomatic aortic stenosis in elderly patients
- To assess the efficacy of a valve clinic based regular follow-up program for patients with severe aortic stenosis