Antigens, Differentiation, T-Lymphocyte; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Gene Regulatory Networks; Inflammation; T Cells; T-Lymphocyte Subsets
Our long-term research interest is to characterize molecular mechanisms that regulate the development and function of T lymphocytes. With our studies we aim to provide important and medical relevant insight into the regulation of T cell-mediated immunity. In ongoing studies we address the following research topics:
• Histone deacetylase function in T cell-mediated immunity
• Transcriptional control of T cell development and function
• Regulation of T cell lineage identity and integrity
For more information please visit: www.meduniwien.ac.at/immunobiology
Techniques, methods & infrastructure
The experimental strategies to address our research interests include immunological tools, biochemical and molecular approaches, next generation sequencing, retroviral-mediated gene transduction into hematopoietic stem cells, and mouse molecular genetics tools.