Professor of Surgery
Department of Surgery – Research Laboratories
Anna Spiegel Center of Translational Research
Währinger Gürtel 18-20, 1090 Vienna, Austria
Phone: +43 (0)1 40400 - 73513
FAX: +43 (0)1 40400 - 73593
Tumorimmunology, tumor immunoediting, apoptosis, phagocytosis, inflammation and its resolution.
Immunogenic Cell Death in Cancer Therapy
Our work focuses on tumor immunology and drug resistance, with particular interest in breast cancer and colon cancer.
We examine the effect of cancer therapy on the immune system, with special focus on the immune response to therapy-induced cell death.
Our team has shown that the immediate response of the complement system within in the first few days of chemotherapy correlates with the final success of the treatment.
Currently, we are analyzing the role of complement for chemotherapy induced cell death in vitro.
Benkoe T, Baumann S, Weninger M, Pones M, Reck C, Rebhandl W, Oehler R. Comprehensive evaluation of 11 cytokines in premature infants with surgical necrotizing enterocolitis. PLoS One. 2013;8(3):e58720. doi:
Arnold T, Michlmayr A, Baumann S, Burghuber C, Pluschnig U, Bartsch R, Steger G, Gnant M, Bergmann M, Bachleitner-Hofmann T, Oehler R. Plasma HMGB-1 after the initial dose of epirubicin/docetaxel in cancer. Eur J Clin Invest. 2013 Mar; 43(3):286-91. doi: 10.1111/eci.12043.
Bilalic S, Michlmayr A, Gruber V, Buchberger E, Burghuber C, Böhmig GA, Oehler R. Lymphocyte activation induces cell surface expression of an immunogenic vimentin isoform. Transpl Immunol. 2012 Oct;27(2-3):101-6
Michlmayr A, Bachleitner-Hofmann T, Baumann S, Marchetti-Deschmann M, Rech-Weichselbraun I, Burghuber C, Pluschnig U, Bartsch R, Graf A, Greil R, Allmaier G, Steger G, Gnant M, Bergmann M, Oehler R. Modulation of plasma complement by the initial dose of epirubicin/docetaxel therapy in breast cancer and its predictive value. Br J Cancer. 2010 Oct 12;103(8):1201-8