Professor of Pathophysiology and Allergy Research
Department of Pathophysiology and Allergy Research
Center for Pathophysiology, Infectiology and Immunology
Währinger Gürtel 18-20, 1090 Vienna, Austria
Phone: +43 (0)1 40400 - 51320
FAX: +43 (0)1 40400 - 51300
Allergy research, characterization of mite allergens, production of hypoallergenic mite allergen derivatives, improvement of diagnosis and immunotherapy of mite allergy.
Molecular, immunological and structural characterization of mite allergens
Our major goal is the molecular characterization of house dust mite allergens, the use of these molecules to study the immunological mechanisms underlying house dust mite allergy and the improvement of diagnosis and therapy of mite allergy.
We will analyze the importance of the individual house dust mite allergens regarding their allergenic activity, frequency of IgE recognition in different populations and contribution to mite-specific IgE responses in patients.
This should allow us to define the panel of house dust mite allergens necessary for diagnosis and therapy of mite allergy.
Allergens necessary for immunotherapy will be modified into hypoallergenic derivatives and tested for their potential as vaccine candidates.