Professor of Tropical Medicine
Laura Bassi Centre of Expertise OCUVAC
Department for Specific Prophylaxis & Tropical Medicine
Center for Pathophysiology, Infectiology & Immunology
Kinderspitalgasse 15, 1090 Vienna, Austria
Phone: +43 (0)1 40160 - 38261
FAX: +43 (0)1 40160 - 938293
Ocular surface diseases, trachoma, uveitis, ocular allergies, ocular infections.
Ocular Immunology and Infection
The centre for ocular inflammation and infection bridges preclinical and clinical studies in the field of neglected and/or orphan ocular diseases.
Our long-term research interest is to develop therapeutics for ocular surface and intraocular diseases. Currently we are investigating the conjunctiva together with conjunctiva-associated lymphoid tissue as mucosal immunization site targeting ocular surface diseases as well as adjuvants and delivery platforms suitable for ocular application.
In the clinical part of our research that operates 2 days a week we aim to accurately diagnose and successfully treat patients with any form of inflammation affecting the eye or its surrounding areas including allergies and infections in close collaboration with patient support groups.
Clinical trials are performed for orphan ocular designations especially uveitis.
The experimental strategies to address our research interests include animal models, biochemical and molecular approaches and imaging in vivo (human, animal) and in vitro.
More information about the various research projects can be found www.ocuvac.com
Stein E, Inic-Kanada A, Belij S, Montanaro J, Bintner N, Schlacher S, Mayr UB, Lubitz W, Stojanovic M, Najdenski H, Barisani-Asenbauer T. In vitro and in vivo uptake study of Escherichia coli Nissle 1917 bacterial ghosts: cell-based delivery system to target ocular surface diseases. Invest Ophthalmol Vis Sci. 2013 Sep 24;54(9):6326-33.
Barisani-Asenbauer T, Inic-Kanada A, Belij S, Marinkovic E, Stojicevic I, Montanaro J, Stein E, Bintner N, Stojanovic M. The ocular conjunctiva as a mucosal immunization route: a profile of the immune response to the model antigen tetanus toxoid. PLoS One. 2013 Apr 26;8(4):e60682
Barisani-Asenbauer T, Maca SM, Mejdoubi L, Emminger W, Machold K, Auer H. Uveitis- a rare disease often associated with systemic diseases and infections- a systematic review of 2619 patients. Orphanet J Rare Dis. 2012 Aug 29;7:57