Institute of Medical Genetics
Medical University of Vienna
Währinger Strasse 10
1090 Vienna
Austria
juergen.neesen@meduniwien.ac.at
human genetics, molecular genetics, molecular biology, cytogenetics, animal genetics
male fertility, spermatogenesis, genetic diseases,
DNA, RNA, Protein analyses, sequencing (Sanger, Next generation sequencing), Array technology (expression analyses, CGH), genetic analysis of single cells, microscopy,
PCR, western blotting, cell culture, generation of knock-out mice
Rashid S., Grzmil P., Drenckhahn J.-D., Meinhardt A., Adham I., Engel W. and Neesen J. (2010) Disruption of the murine dynein light chain gene Tcte3-3 results in asthenozoospermia. Reproduction 139(1):99-111
Grzmil P., Enkhbaatar Z., l Gundsambuu B., Oidovsambuu O., Yalcin S.,. Meyer BI., Wolf S., Engel W. and Neesen J. (2010) Mouse Arfgef2 is essential for early embryonic development. Int J Dev Biol.;54(8-9):1259-66)
Rashid S., Breckle R., Hupe M., Geisler S., Doerwald N., Neesen J. (2006). The murine Dnali1 gene encodes a flagellar protein that interacts with the cytoplasmic dynein heavy chain 1. Mol Reprod Dev. 73(6):784-94.
Mendoza-Lujambio I., Burfeind P., Dixkens C., Meinhardt A., Hoyer-Fender S., Engel W., Neesen J. (2002). The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse. Hum. Mol. Genet. 11: 1647-58.
Neesen J., Kirschner R., Ochs M., Schmiedl A., Habermann B., Mueller C., Holstein AF., Nuesslein T., Adham I., Engel W. (2001). Disruption of an inner arm dynein heavy chain gene results in asthenozoospermia and reduced ciliary beat frequency. Hum. Mol. Genet. 10: 1117-28.