Obesity, Insulin resistance, Type 2 diabetes mellitus
Inflammation and metabolism
Polyunsaturated fatty acids
Signal transduction, gene regulation
Lipid disorders
Nutritional Medicine
Inborn Diseases of Metabolism

techniques and infrastructure of the research group:

Mouse models of obesity and cardiometabolic diseases
Clinial studies
Basic biochemical, molecular and cell biological techniques
(cell culture, flow cytometry, immunoblotting, immunohistochemistry, quantitative
real-time RT-PCR, ELISA, etc.)

Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue.
Zeyda M, Wernly B, Demyanets S, Kaun C, Hämmerle M, Hantusch B, Schranz M, Neuhofer A, Itariu BK, Keck M, Prager G, Wojta J, Stulnig TM.
Int J Obes (Lond). 2012 Jul 17. doi: 10.1038/ijo.2012.118. [Epub ahead of print]

Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance.
Kiefer FW, Zeyda M, Gollinger K, Pfau B, Neuhofer A, Weichhart T, Säemann MD, Geyeregger R, Schlederer M, Kenner L, Stulnig TM.
Diabetes. 2010 Apr;59(4):935-46. Epub 2010 Jan 27.

CC chemokine and CC chemokine receptor profiles in visceral and subcutaneous adipose tissue are altered in human obesity.
Huber J, Kiefer FW, Zeyda M, Ludvik B, Silberhumer GR, Prager G, Zlabinger GJ, Stulnig TM.
J Clin Endocrinol Metab. 2008 Aug;93(8):3215-21. Epub 2008 May 20.

Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production.
Zeyda M, Farmer D, Todoric J, Aszmann O, Speiser M, Györi G, Zlabinger GJ, Stulnig TM.
Int J Obes (Lond). 2007 Sep;31(9):1420-8. Epub 2007 Jun 26.

Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin.
Geyeregger R, Zeyda M, Bauer W, Kriehuber E, Säemann MD, Zlabinger GJ, Maurer D, Stulnig TM.
Blood. 2007 May 15;109(10):4288-95. Epub 2007 Jan 25.