Univ. Prof. DI Dr. Leopold Schmetterer
Medical University of Vienna
Department of Clinical Pharmacology
Waehringer Guertel 18-20
Phone: +43 (0)1 40400-2981
Fax: +43 (0)1 40400-2998
Know-how and research interests
The aim of our research group is to gain new insight into the pathogenesis of eye diseases and develop new treatment modalities. A specific focus is directed towards new imaging modalities in glaucoma, diabetic retinopathy, age-related macular degeneration, dry eye symptom, and drug delivery.
Techniques and infrastructure of the research group:
Laser Doppler flowmetry, retinal vessel diameter measurement, Laser interferometric measurement of choroidal blood flow, impression cytology, various OCTs for imaging of the anterior and posterior segment, measurement of tear film osmolarity, laser Doppler velocimetry, measurement of retinal oxygenation, measurement of macular pigment optical density,...
5 selected publications:
Pemp B, Weigert G, Karl K, Petzl U, Wolzt M, Schmetterer L, Garhofer G. Correlation of flicker-induced and flow-mediated vasodilatation in patients with endothelial dysfunction and healthy volunteers. Diabetes Care. 2009;32:1536-41.
Pemp B, Polska E, Garhofer G, Bayerle-Eder M, Kautzky-Willer A, Schmetterer L. Retinal blood flow in type 1 diabetic patients with no or mild diabetic retinopathy during euglycemic clamp. Diabetes Care. 2010;33:2038-42.
Schmidl D, Boltz A, Kaya S, Werkmeister R, Dragostinoff N, Lasta M, Polska E, Garhöfer G, Schmetterer L. Comparison of choroidal and optic nerve head blood flow regulation during changes in ocular perfusion pressure. Invest Ophthalmol Vis Sci. 2012;53:4337-46.
Lasta M, Pemp B, Schmidl D, Boltz A, Kaya S, Palkovits S, Werkmeister R, Howorka K, Popa-Cherecheanu A, Garhöfer G, Schmetterer L. Neurovascular dysfunction precedes neural dysfunction in the retina of patients with type 1 diabetes. Invest Ophthalmol Vis Sci. 2013;54:842-7.
Boltz A, Told R, Napora KJ, Palkovits S, Werkmeister RM, Schmidl D, Popa-Cherecheanu, Garhöfer G, Schmetterer L. Optic nerve head blood flow autoregulation during changes in arterial blood pressure in healthy young subjects. PLoS One, 2013