After initial elucidation of endocrine regulatory mechanisms and principal metabolic pathways in the midst of the 20th century, advances in molecular biology and experimental methodology have paved the way for further scientific progress. A prerequisite for this progress is the availability of trained researchers. It is the aim of the thematic programs "Endocrinology and Metabolism" and "Clinical Endocrinology, Metabolism and Nutrition" to train students for modern and comprehensive scientific challenges. Scientifically as well as clinically, the topics related to endocrinology and metabolism extend into many subjects including not only internal medicine, but also gynecology, pediatrics, surgery and nutritional medicine. Thematically, the programs comprise this broad field in basic sciences, diagnostics and novel therapeutic approaches.