Supervisor: Christian Göbl
Committee: Florian Kiefer, Herbert Kiss
Department: Obstetrics & Gynecology, Division of Gynecologic Endocrinology & Reproductive Medicine
E-mail: marlene.hager@meduniwien.ac.at
Tel: +43 (0)1 40400 - 28160
Current academic degree: M.D.
Previous University and Subject: Medical University of Vienna
Thesis since: 12/2018
In diagnostic evaluation of sterility, usually diagnostic laparoscopy including chromopertubation and diagnostic hysteroscopy – the latter for the exclusion of intrauterine abnormalities – are performed. Assessment of Fallopian tube patency is one of the key elements in infertility evaluation. In the last years, diagnostic hysteroscopy, also performed in an outpatient setting, has gained importance. Maximizing the informative output of this procedure would be highly beneficial for the patient. In this prospective study, routine hysteroscopy and laparoscopy including chromopertubation will be conducted. Before and after the hysteroscopy, an additional transvaginal sonography will be performed in order to assess a possible pre- to posthysteroscopic shift in the amount of intraabdominal hysteroscopic fluid in the pouch of Douglas. It is assumed that women with bilateral Fallopian tube occlusion will not reveal this fluid shift. Directly after the ultrasound, laparoscopy including chromopertubation will be performed in the course of clinical routine to confirm or rule out the findings of the ultrasound. A calculated sample size of 115 patients with sterility/infertility will be recruited for the study. Data will be acquired using a studyspecific case report form. Using crosstabs, the overall accuracy, specificity and sensitivity, positive and negative predictive values and their 95% confidence intervals will be provided for bilateral Fallopian tube occlusion.
Clinical studies