HASENÖHRL Timothy

Resistance Exercise as a Supportive Care and Side Effect Management in Breast Cancer Survivors suffering from Breast Cancer Related Lymphedema

Aim of this project is to conduct a comprehensive resistance exercise (RE) intervention project with breast cancer survivors (BCS) suffering from breast cancer related lymphedema (BCRL).
 
The systematic approach to this cumulative PhD project will first be the publication of a systematic review and - in case that the currently published literature is suitable - an additional meta-analysis about the current scientific knowledge in this field. This review will help to identify a relevant research gap regarding resistance exercise in this particular patient population.
 
The second step will be a resistance exercise intervention study with BCS. The details regarding the RE intervention are currently unknown and will be based on the findings of the systematic review and will aim on finding a resistance exercise stimulus which will enable optimized effects on body composition, physical performance and quality of life while simultaneously minimizing potential negative effects on the BCRL.

The third and final step of this PhD project will be a cross-sectional analysis with BCS with the aim of identifying factors which influence patient compliance and adherence to resistance exercise recommendations after completing their in-patient rehabilitation stay.

Other than in pharmaceutical treatments, in exercise interventions constant active collaboration of the participants is of major importance for being successful. This means that patients are supposed to find practical solutions to implement their training in their post-treatment and post-rehabilitation life. Therefore, it is necessary to know factors which influence the practicability for as well as the willingness of the patients to self-responsibly undertake resistance exercise after the in-patient rehabilitation stay. These factors might be dependent on the health care and social security system of the respective patient population and it is therefore recommended to identify those factors for BCS in their living environment. The findings of this work are supposed to show how post-treatment exercise offers for BCS suffering from BCRL are supposed to look like at best in Austria.

Methods and Skills:

clinical studies; functional asssessment of physical performance; lymphedema assessment; exercise intervention

Publications:

Hasenoehrl T, Palma S, Ramazanova D, Koelbl H, Dorner TE, Keilani M, Crevenna R. Resistance Exercise and Breast Cancer Related Lymphedema – a Systematic Review Update and Meta-Analysis. Support Care Cancer. 2020 May 15; Online ahead of print.

Keilani M, Kainberger F, Pataraia A, Hasenöhrl T, Wagner B, Palma S, Cenik F, Crevenna R. Typical aspects in the rehabilitation of cancer patients suffering from metastatic bone disease or multiple myeloma. Wien Klin Wochenschr. 131: 567-575, 2019

Hasenoehrl T, Keilani M, Palma S, Crevenna R. Resistance exercise and breast cancer related lymphedema - a systematic review update. Disabil Rehabil. 42: 26-35, 2020

Keilani M,  Hasenoehrl T,  Baumann L, Ristl R, Schwarz M, Sedghi Komandj T, Marhold M, Crevenna R. Effects of resistance exercise in prostate cancer patients: a meta-analysis. Support Care Cancer 25: 2953-2968, 2017

Hasenoehrl T, Keilani M, Sedghi Komanadj T, Mickel M, Margreiter M, Marhold M, Crevenna R. The effects of resistance exercise on physical performance and health-related quality of life in prostate cancer patients: a systematic review. Support Care Cancer 23: 2479-97, 2015