Study design: 708 consecutive bariatric surgery patients (78% female ,22% male, mean BMI 46 kg/m2 preoperatively) underwent laparoscopic roux-en-Y gastric bypass between 2005 and 2012 and will be retrospectively evaluated for changes in their homocysteine levels at the timepoints preoperatively, at 3, 6, 9, 12, 18,24, 36,48, 60, 72, 84 and 96 months postoperatively (mean follow-up: 27 months).

Aim: ln this current trial we hypothesize that bariatric surgery, especially roux-en-Y gastric bypass, results in postoperative changes of homocysteine levels. Furthermore, we will provide a systematic analysis of various timepoints after surgery with adequate long term follow-up.

Methods and Skills:

Clinical studies; retrospective analysis