Description

Molecular and cellular defense mechanisms of the innate and the adaptive immune system protect organisms against harmful pathogens and against the development of malignant cells. However, overreactions of the immune system are responsible for the establishment of immune-mediated diseases such as allergy, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, diabetes, psoriasis and atherosclerosis. It is of enormous importance for contemporary biomedical science to increase the knowledge about the mode of action of the immune system in order to design better therapies for the cure of these life-threatening diseases.

Within the program, PhD students will have the opportunity to work on cutting-edge research projects ranging from basic aspects of immune cell development and function to infection immunology, from the analysis of disease mechanisms in autoimmunity and allergy to the development of therapeutic strategies of immune-related diseases. Furthermore, dependent on the research projects, PhD students will learn and apply cutting-edge technologies including NGS approaches, single-cell RNA-sequencing, proteomics, a braod spectrum of immunological methods and multicolor flow cytometry. Currently, approximately 30 research laboratories hosting more than 100 PhD students are part of the program. Thus, students in the program can either focus on basic research projects to investigate fundamental immunological processes or perform disease-oriented research.

For a list of participating laboratories, please <click here>.

For a description of course offered, please <click here>.

Recommended Literature:

For a general overview and introduction into the immune system

• Cellular and Molecular Immunology, 9th Edition, Abul Abbas, Andrew Lichtman, Shiv Pillai. Saunders, 2017.

"Molecular and Cellular Immunology" is also used as teaching book in the Basic Lecture Immunology

• Janeway’s Immunobiology – The Immune system in health and disease. 9th Edition, Kenneth M Murphy, Paul Travers, Mark Walport, Garland Science Textbook 2016.

For an in-depth insight on a particular subject

• all the major research journals in the field of immunology