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Herzlich Willkommen auf der Homepage des Instituts für Pathophysiologie und Allergieforschung!


Gegründet im Jahr 1873
gehört das IPA zu den ältesten Forschungsinstituten der Medizinischen Universität Wien.
Derzeit haben wir 130 interdisziplinäre und internationale MitarbeiterInnen, deren Forschungsarbeit darauf abzielt, pathophysiologische Vorgänge besser zu verstehen und daraus innovative Konzepte zu entwickeln, die der Diagnose, Prophylaxe und Therapie von Erkrankungen dienen. Zusätzlich legen wir Wert auf höchste Qualität in der Lehre und Ausbildung von MedizinerInnen und NaturwissenschafterInnen. Darüber hinaus bietet das IPA die postgradualen
Ausbildungen zu FachärztInnen für Pathophysiologie und Immunologie an.

Research News

 
   

Samadi N, Klems M, Heiden D, Bauer R, Kitzmüller C, Weidmann E, Ret D, Ondracek AS, Duschl A, Horejs-Hoeck J, Untersmayr E. Allergy. 2019 Aug 24. doi: 10.1111/all.14030. PMID: 31444907

 
 

Samadi N, Polak D, Kitzmüller C, Steinberger P, Zlabinger GJ, Jahn-Schmid B, Bohle B. Eur J Immunol. 2019. doi: 10.1002/eji.201848057. PMID: 31332790

 
 

July 30, 2019, Nature Communications 10, 3298, by Jordakieva et al.: Antiacids drugs prime subsequent anti-allergy prescriptions. 30% of 30-years old, and 33% of 60-year old Austrians are treated with gastric acid-inhibitors. As a continuation of their previous works, the team around Erika Jensen-Jarolim performed a population-wide study in Austria and found a significant correlation between the intake of these drugs and symptoms of respiratory allergies, treated by H1R blockers and allergen-specific immunotherapy. See https://www.nature.com/articles/s41467-019-10914-6

 
 

Sublingual immunotherapy with recombinant Mal d 1 downregulates the allergen-specific Th2 response. Kitzmüller C, Jahn-Schmid B, Kinaciyan T, Bohle B. Allergy. 2019 Aug;74(8):1579-1581. doi: 10.1111/all.13779. Epub 2019 Apr 10.

 
 

A study published in Computational and Structural Biotechnology Journal and conducted by Anastasia Meshcheryakova from the Systems Biology and Pathophysiology Group of Diana Mechtcheriakova together with colleagues from the Medical University of Vienna and the multidisciplinary team of international experts made an effort to look from another angle on potential therapeutic checkpoints for epithelial ovarian cancer and propose that assessment of the sphingolipid and lysophosphatidate systems in conjunction with the local immune response may lead to novel stratifying and targeting strategies. This offers the power for improving the efficacy of existing therapies and possibly immunotherapies.

 
 

News & Activities

 
   

The ÖGAI meeting was held in Graz from November 21-23, 2019.

 
 

Gabriela Sanchez-Acosta and Christina Weichwald received oral presentation awards, Tanja Kalic and Verena Köhler got awarded poster discussion awards, Piotr Humeniuk and Christoph Nagl received poster prizes for their presentations at the annual congress of the European Academy for Allergy and Clinical Immunology (EAACI).

 
 

Pawel Dubiela, a former member from the MCCA PhD programme (Group Karin Hoffmann-Sommergruber), has received the “Best PhD Thesis award 2018” during the XI Training conference of the Polish Society of Allergology on May 8, 2019 in Wisla, Poland  based on his outstanding achievements during his PhD Studies. Congratulations!

 
 

Die am “Joint Programming Initiative - A Healthy Diet for a Healthy Life (JPI HDHL)” beteiligten Mitgliedsländer (derzeit 25 EU Mitgliedsländer, Assoziierte Länder, Israel, Kanada und Neuseeland) haben es sich um Ziel gesetzt, durch koordinierte Maßnahmen und Forschungsinitiativen zur öffentlichen Gesundheit, zur Vermeidung von ernährungsbedingten Erkrankungen und generell zur Steigerung der Lebensqualität und Verlängerung der produktiven Lebensspanne beizutragen.

 
 

For the work on the role of the Calcium-Sensing Receptor in colon inflammation, Dr. Martin Schepelmann (from the group Prof. Enikö Kallay) received the Science Award for the best submitted work as well as a Mentoring Award from the Austrian Society of Endocrinology (ÖGES) at the society’s 24th annual meeting in Graz, Austria (24.-26.4.201) where he presented the research both as poster and oral communication. This is the second year in a row that Dr. Schepelmann has won the ÖGES Science Award. Congratulations!