Aim of the project "Prodrom" is creating a device to identify genetical and enviromental factors .
Patients with psychotic disorders such as schizophrenia, usually experience early signs of psychosis for 1-5 years prior to the first episode of frank illness. This early state is known as at risk Patients with psychotic disorders such as schizophrenia, usually experience early signs of psychosis for 1-5 years prior to the first episode of frank illness. This early state is known as at risk mental state (ARMS) or prodrome. Individuals with ARMS appear to be at extremely high risk of developing psychosis; about one-third will do so, while two-thirds will not make a transition to psychosis and their at-risk symptoms will either stay the same or improve. It is unclear why only a subset of those who are highly vulnerable to psychosis go on to develop the illness.
There is increasing evidence that aetiological models of schizophrenia need to incorporate the role of genetic, social, psychological and biological factors, and to clarify how they interact. In this study, state-of- the-art methods will be used to examine the genetic, psychological and physiological interactions in individuals at high risk of psychosis. The ultimate aim of this work-package is to deliver a tool that can be used to help identifying genetic and environmental factors that, when they interact, predict who is more likely to develop schizophrenia.mental state (ARMS) or prodrome.
Scientist of the Medical University of Vienna
The Medical University of Vienna is project partner under the leadership of Ao.Univ. Prof. DDr. Gabriele Sachs, Department of Psychiatry and Psychotherapy, Division of Social Psychiatry.
Ao.Univ.Prof. Dr. Harald Aschauer
Mag.a Monika Schlögelhofer (klinische Psychologin)
Dr.in Iris Lasser (klinische Psychologin)
Dr.in Bernadette Winklbaur (klinische Psychologin)
Projekt coordinator: Prof. Jim van Os, Universität Maastricht, Niederlande.
Project partners: 25
|Topic||Genetic and Environmental Interactions./Collaborative project|
|Project duration||2010 - 2015|
|Funding Volume, total||Euro 11.616.855.-|
|Funding Volume, Medical University of Vienna||Euro 108.916.-|