Department of Dermatology
Position: Master Student
david.samardzic@meduniwien.ac.at
Keywords
Bacteriophages; Chemistry, Pharmaceutical; Extracellular Matrix Proteins; Inflammation; Molecular Mechanisms of Pharmacological Action; Single-Cell Analysis; Skin
Research group(s)
- Tissue Homeostasis Group
Head: Karin Pfisterer
Members:
Research interests
The main interests of my research group spread from changes in extracellular matrix organisation of inflammatory skin diseases to microbial homeostasis on healthy and pathological skin. We are focusing on determining the differences of the extracellular matrix and cytoskeleton of epidermal and dermal cells in chronic skin diseases like atopic dermatitis and psoriasis on a single cellular level. One of our research topics is also the penetration of aeroallergens through damaged skin lesions in patients with atopic dermatitis. One of our findings does focus on the microbiological systems of the skin bioflora including bacteria, fungi and bacteriophages. My special interest lies in the interaction between allergens and immune sentinels of the skin in vivo and in vitro.
Techniques, methods & infrastructure
Wet lab
- Pharmaceutical compounding
- Analytical chemistry
- Synthetical chemistry
- Molecular Biology techniques
- Cell and tissue culture
- Bacterial culture
Data Analysis
- basic bioinformatic skills with R
- single cell RNA sequencing
Selected publications
- Pfisterer, K. et al. (2023) ‘Non-IgE-reactive allergen peptides deteriorate the skin barrier in house dust mite-sensitized atopic dermatitis patients’, Frontiers in Cell and Developmental Biology, 11. Available at: http://dx.doi.org/10.3389/fcell.2023.1240289.